In 1963, Academician Chen Zhongwei and Professor Qian Yunqing joined forces to achieve the world's first successful severed limb replantation. Through generations of unwavering dedication, our hospital has emerged as the largest replantation center in the world and is revered as the cradle of limb replantation in China. 

In 1978, Professor Yu Zhongjia pioneered the transplantation of a patient's toe to the amputation stump of the forearm, resulting in the creation of a functional hand capable of sensation and movement. This groundbreaking procedure earned international recognition as the "China Hand". Building upon this achievement, Shanghai Institute of Microsurgery on Extremities was founded in 1987, along with the establishment of Shanghai International Microsurgery Training Center on Extremities, serving as a premier institution for training microsurgical techniques.

In 1994, limb microsurgery was designated as Shanghai Key Leading Discipline, catalyzing advancements in the entire field. In June 2001, with approval from the Shanghai Municipal Government, the Department of Orthopedics was designated as Shanghai Traumatic Orthopedics Clinical Center. By 2007, it had become a Key Construction Discipline of Shanghai Jiao Tong University under the 211 Project. Concurrently, the establishment of Institute of Traumatic Orthopaedics of Shanghai Jiao Tong University formalized the recognition of Orthopedics as a National Key Discipline. Over the years, Shanghai Institute of Microsurgery on Extremities has garnered over 20 awards at or above the provincial and ministerial levels, including one first prize for the National Invention Award, two second prizes for the National Science and Technology Progress Award, and three first prizes for the Shanghai Science and Technology Progress Award. Additionally, six individuals have been honored with talent training programs at or above the municipal level, including Excellent Young Scientists Fund by the National Natural Science Foundation of China, Shanghai Leading Talents, Shanghai Outstanding Academic Leaders, Shanghai Rising-Star Program, and Outstanding Young Talents by the Shanghai Municipal Health Commission.

Shanghai Institute of Microsurgery on Extremities boasts a dedicated research team comprising full-time researchers and clinicians. Over the years, it has conducted extensive research into the pathogenesis of major orthopedic diseases, the treatment and repair of related injuries, stem cell tissue engineering, extracellular vesicles and tissue and organ regeneration and repair, as well as the development and transformation of orthopedic biomaterials, yielding significant results. These achievements have consistently placed the Institute among the top-ranking institutions in China in terms of scientific and technological influence. 

With over 3,000 square meters of scientific research facilities, the Institute primarily houses four advanced technical platforms: cell biology, histomorphology, molecular biology, and biomaterials, all equipped with state-of-the-art facilities. Adhering to international standards, the Institute has established a tissue and blood sample bank for orthopedic-related diseases, along with an epidemiological investigation and follow-up database. Additionally, the implementation of the PI system and technology platform sharing system enables researchers and clinicians to focus on conducting systematic research addressing the major basic and clinical challenges in orthopedics.

Shanghai Institute of Microsurgery on Extremities welcomes talented individuals from both domestic and international backgrounds to join our team!