CHEN Yunfeng  

  • Chief Physician, Doctoral Supervisor, Professor
  • Department: Orthopedics
  • Research Area: Surgery (Orthopedics)
  • Research Interests: Implant-related bone infection; Limb trauma; Shoulder injury; Proximal humeral fracture; Acromioclavicular joint dislocation
  • Contact: chenyf@sjtu.edu.cn
  • PhD from Shanghai Jiao Tong University, 2012
  • MD from Shanghai Second Medical University, 2002
  • Chief Physician, Department of Orthopedics, Shanghai Sixth People's Hospital
  1. Luo Z, Shi T, Chen Y#. Quorum Sensing Interference Assisted Therapy-Based Magnetic Hyperthermia Amplifier for Synergistic Biofilm Treatment. Small. 2023 , doi: 10.1002/smll.202304836.                          
  2. Ding C, He R, Chen Y#. Bacterial Outer Membrane-Based Biomimetic Immune Adaptors: Mild Immunomodulatory and Bacterial Targeted Delivery Strategy Against Implant-Related Infections. Adv. Funct. Mater. 2023, https://doi.org/10.1002/adfm.202304168
  3. Wang Q, Sheng N,Chen Y#. Effect of Fibular Allograft Augmentation in Medial Column Comminuted Proximal Humeral Fractures: A Randomized Controlled Trial. J Bone Joint Surg Am. 2023, doi:10.2106/JBJS.22.00746. 
  4. Ruan Z, Zhang C, Chen Y#. Gold nanoclusters-loaded hydrogel formed by dimeric hydrogen bonds crosslinking: A novel strategy for multidrug-resistant bacteria-infected wound healing. Mater Today Bio. 2022, doi: 10.1016/j.mtbio.2022.100426.
  5. Shi T,Ruan Z ,Chen Y#. Erythrocyte Membrane-Enveloped Molybdenum Disulfide Nanodots for Biofilm Elimination on Implants via Toxin Neutralization and Immune Modulation, J. Mater. Chem. B, 2022, doi: 10.1039/d1tb02615a.
  6. Zhang C, Chu G, Chen Y#, Biomimetic Self-Assembling Metal-Organic Architectures with Non-Iridescent Structural Coloration for Synergetic Antibacterial and Osteogenic Activity of Implants. ACS Nano. 2022, doi: 10.1021/acsnano.2c06030.
  7. Chu G, Zhang C, Chen Y#. A Gold Nanocluster Constructed Mixed-Metal Metal−Organic Network Film for Combating Implant-Associated Infections, ACS Nano, 2020,doi: 10.1021/acsnano.0c06446.
  8. Chen C, Chu G, Chen Y#.Porphyrin Alternating Copolymer Vesicles for Photothermal Drug- Resistant Bacterial Ablation and Wound Disinfection, ACS Appl. Bio Mater., 2020,doi: 10.1021/acsabm.0c01343.
  9. Zhu Y, Wang Y, Chen Y#. Comparison of exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells and synovial membrane-derived mesenchymal stem cells for the treatment of osteoarthritis, Stem Cell Research & Therapy, 2017,doi: 10.1186/s13287-017-0510-9.
  10. Wang Q, Sheng N, Chen Y#. The neck-shaft angle is the key factor for the positioning of calcar screw when treating proximal humeral fractures with a locking plate, Bone Joint J, 2020,doi: 10.1302/0301-620X.102B12.BJJ-2020-0070.R1.
  11. Zhu Yu, Hsueh, Chen Y#. A prospective study of coracoclavicular ligament reconstruction with autogenous peroneus longus tendon for acromioclavicular joint dislocations,Journal of Shoulder and Elbow Surgery, 2018, doi: 10.1016/j.jse.2017.12.009.
  12. Wang QK, Liu YF, Chen YF#. Optimal viewing angles of intraoperative fluoroscopy for detecting screw
  13. penetration in proximal humeral fractures: a cadaveric study. BMC Musculoskelet Disord. 2018,doi: 10.1186/s12891-018-2247-8.
  14. Wang QK, Hu J, Chen Y#. Proximal third humeral shaft fractures fixed with long helical PHILOS plates in elderly patients:benefit of pre-contouring plates on a 3D-printed model-a retrospective study. J Orthop Surg Res,2018, doi: 10.1186/s13018-018-0908-9.
  15. Zeng LQ, Zeng LL, Chen YF#. Influence of Medial Support Screws on the Maintenance of Fracture Reduction after Locked Plating of Proximal Humerus Fractures. Chin Med J 
  • 01/01/2022-12/31/2025
    National Natural Science Foundation of China(General project), ¥550,000, 82172455
    Study on the Effect and Mechanism of Magnetic Biomimetic Nanosystems in the Treatment of Implanted-related Bone Infections
    Role: Project leader
  • 04/01/2022-3/31/2025
    Shanghai Municipal Commission of Science and Technology,(Science and Technology Innovation Action Plan), ¥250,000,22S31900200
    Development of a new type of ultrasound medullary endoscopy and its application in the integrated diagnosis and treatment of osteomyelitis
    Role: Project leader
  • 04/01/2022-3/31/2025
    Shanghai Shenkang Hospital Development Center Clinical Science and Technology Innovation Project, ¥500,000,SHDC12021117
    Early diagnosis and treatment of humeral head necrosis after internal fixation surgery for proximal humeral fractures: exploration of the application of new technologies
    Role: Project leader                
  1. [Yunfeng Chen,Cheng Ding] (2023), “Application and preparation method of a mixed metal organic framework”, PCT/CN115926187 B; ZL 202211727686.5
  2. [Yunfeng Chen,Guangyu Chu] (2022), “A nano antibacterial coating material based on nano gold clusters and its preparation method”, PCT/CN112190767 B; ZL 202011003783.0