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CHEN Shiwen
- Graduate Supervisor, Professor
- Department: Neurosurgery
- Research Area: Surgery (Neurosurgery)
- Research Interests: Traumatic Brain Injury, Cerebrovascular Diseases
- Contact: chenshiwen@126.com
- Chief physician, Department of Neurosurgery, Shanghai Sixth People's Hospital, 2014
- Associate chief physician, Department of Neurosurgery, Shanghai Sixth People's Hospital, 2007
- Attending physician, Department of Neurosurgery, Shanghai Sixth People's Hospital, 2005
- Attending physician, Department of Neurosurgery, Jinan Military General Hospital, 1998
- Resident doctor, Department of surgery, Shandong Caoxian People's Hospital, 1994
- MD from Second Military Medical University, 2005
- MA from Second Military Medical University, 1998
- BCM from Jining Medical University, 1994
- Vice Director, Department of Neurosurgery, Shanghai Sixth People's Hospital
- Vice President, Shanghai Sixth People's Hospital Anhui Branch
- Zhang C, Xu C, Jing Y, Cao H, Wang X, Zhao J, Gong Q, Chen S: Deferoxamine Induces Autophagy Following Traumatic Brain Injury via TREM2 on Microglia. Mol Neurobiol 2023, DOI:10.1007/s12035-023-03875-x (corresponding author)
- Zhao J, Wang W, Yan K, Zhao H, Zhang Z, Wang Y, Zhu W, Chen S: RNA-seq reveals Nup62 as a potential regulator for cell division after traumatic brain injury in mice hippocampus. PeerJ 2023, 11:e14913(corresponding author)
- Zhang C, Chen S: Role of TREM2 in the Development of Neurodegenerative Diseases After Traumatic Brain Injury. Mol Neurobiol 2023, 60:342-54.( corresponding author)
- Gong Q, Cai L, Jing Y, Wang W, Yang D, Chen S, Tian H: Urolithin A alleviates blood-brain barrier disruption and attenuates neuronal apoptosis following traumatic brain injury in mice. Neural Regen Res 2022, 17:2007-13. (co-corresponding author)
- Wang K, Jing Y, Xu C, Zhao J, Gong Q, Chen S: HIF-1α and VEGF Are Involved in Deferoxamine-Ameliorated Traumatic Brain Injury. J Surg Res 2020, 246:419-26.( corresponding author)
- Jing Y, Ma X, Xu C, Tian H, Chen S: Repair of dural defects with electrospun bacterial cellulose membranes in a rabbit experimental model, Materials Science and Engineering: C, 2020, 117. (corresponding author)
- Zhao J, Xu C, Cao H, Zhang L, Wang X, Chen S: Identification of target genes in neuroinflammation and neurodegeneration after traumatic brain injury in rats. PeerJ 2019, 7: e8324.( corresponding author)
- Jing Y, Yang D, Fu Y, Wang W, Yang G, Yuan F, Chen H, Ding J, Chen S , Tian H: Neuroprotective effects of serpina3k in traumatic brain injury, Frontiers in Neurology, 2019, 10:1215. (co-corresponding author)
- Xu C, Ma X, Chen S, Tao M, Yuan L, Jing Y: Bacterial cellulose membranes used as artificial substitutes for dural defection in rabbits. Int J Mol Sci 2014, 15:10855-67.( corresponding author)
- Li M, Chen S, Li Y, Chen Y, Cheng Y, Hu D, Tan H, Wu Q, Wang W, Sun Z, Wei X, Zhang J, Qiao R, Zong W, Zhang Y, Lou W, Chen Z, Zhu Y, Peng D, Ding S, Xu X, Hou X, Jia W: Prevalence of unruptured cerebral aneurysms in Chinese adults aged 35 to 75 years: a cross-sectional study. Ann Intern Med 2013, 159:514-21. (Co-first author)
- 01/11/2021-31/10/2023 Shanghai Science and Technology Commission, ¥100,000, 21142202100, Study on pathogen infection screening and medication guidance of mNGS in critically neurosurgical patients
Role: Project leader - 01/07/2019-30/06/2022 Shanghai Science and Technology Commission , ¥200,000, 19ZR1438600, Mechanism of TREM2 regulating mTOR signaling pathway to activate microglia in inflammatory response to traumatic brain injury
Role: Project leader
- [Xia Ma, Heng Wang, Shiwen Chen] (2018), “A Preparation Method of Bacterial Cellulose Film with Moisture-Holding and Bacteriostasis Effect” CN201810315596.2
