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CHEN Hao
- Chief Physician, Doctoral Supervisor, Associate Professor
- Department: Neurosurgery
- Research Area: Neurosurgery
- Research Interests: Basic and clinical research of traumatic brain injur; stroke and neurocritical care; artificial intelligence in neurosurgery
- Contact: hao.chen@shsmu.edu.cn
- Medical Doctor from Shanghai Jiao Tong University School of Medicine, 2017
- Master Degree from Shanghai Jiao Tong University Shcool of Medicine, 2008
- Bachelor of Clinical Medicine from Qingdao University School of Medicine, 2005
- Acting Deputy Director of Neurosurgery, Shanghai Sixth People's Hospital
- Vice Director of Medical Center for Traumatic Brain Injury and Neurocritical Care
- Committee Member of Trauma Group of Chinese Congress of Neurological Surgeons (CCNS)
- Committee Member of Peripheral Nerve Professional Committee of Chinese Medical Doctor Association (CMDA)
- Committee Member of Neural Regeneration and Repair Committee of Chinese Research Hospital Association
- Youth Committee Member of Neurosurgery Branch of Shanghai Medical Association
- Youth Committee Member of Trauma Surgery Branch of Shanghai Medical Association
- Committee Member of Neurosurgery Branch of Shanghai Stroke Association
- Visiting Assistant Professor of Vanderbilt University Medical Center
- Member of American Congress of Neurological Surgeons (CNS)
- Member of International Brain Injury Association (IBIA)
- Zhang G, Lu J, Chen Y, Deng Y, Zhao B*, Chen H*, Xue L*. A lightweight dual-student mean teacher semi-supervised semantic segmentation method for skin lesions. Neural Netw, 2025, 192:107882.
- Hu Z#, Liang Y#, Fan S, Niu Q, Geng J, Huang Q, Hsiao BS, Chen H*, Yao X*, Zhang Y*. Flexible Neural Interface From Non-Transient Silk Fibroin With Outstanding Conformality, Biocompatibility, and Bioelectric Conductivity. Adv Mater, 2024, 36(46):e2410007.
- Zhao J#, Shi Y#, Xue L, Liang Y, Shen J, Wang J, Wu M, Chen H*, Kong M*. Glucose-decorated engineering platelets for active and precise tumor-targeted drug delivery. Biomater Sci, 2023, 11(11):3965-3975. doi: 10.1039/d3bm00326d.
- Xue LX#, Shu LY#, Wang HM, Lu KL, Huang LG, Xiang JY, Geng Z, Zhao YW, Chen H*. miR-181b promotes angiogenesis and neurological function recovery after ischemic stroke. Neural Regen Res, 2023, 18(9):1983-1989. doi: 10.4103/1673-5374.367957.
- Cai L#, Gong Q#, Qi L, Xu T, Suo Q, Li X, Wang W, Jing Y, Yang D, Xu Z, Yuan F, Tang Y, Yang G, Ding J*, Chen H*, Tian H*. ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway. Cell Commun Signal, 2022, 20:56. doi: 10.1186/s12964-022-00862-y.
- Chen H#, Gong Y, Ma Y, Thompson RC, Wang J, Cheng Z*, Xue L*. A Brain-Penetrating Hsp90 Inhibitor NXD30001 Inhibits Glioblastoma as a Monotherapy or in Combination With Radiation. Front Pharmacol, 2020, 11:974. doi: 10.3389/fphar.2020.00974.
- Chen H#, Yuan F, Chen SW, Guo Y, Wang G, Deng ZF, Tian HL*. Predicting posttraumatic hydrocephalus: derivation and validation of a risk scoring system based on clinical characteristics. Metab Brain Dis, 2017, 32(5):1427-1435. doi: 10.1007/s11011-017-0008-2.
- Xue L#, Zhang T, Zhao Y, Geng Z, Chen J, Chen H*. Efficacy and safety comparison of DL 3 n butylphthalide and Cerebrolysin: Effects on neurological and behavioral outcomes in acute ischemic stroke. Exp Ther Med, 2016, 11(5):2015-2020. doi: 10.3892/etm.2016.3139.
- Tian HL#, Guo Y, Hu J, Rong BY, Wang G, Gao WW, Chen SW, Chen H*. Clinical characterization of comatose patients with cervical spine injury and traumatic brain injury. J of Trauma, 2009, 67(6):1305-1310.17. doi: 10.1097/TA.0b013e31819db57c.
- Tian HL#, Chen SW, Xu T, Hu J, Rong BY, Wang G, Gao WW, Chen H*. Risk factors related to hospital mortality in patients with isolated traumatic acute subdural haematoma: analysis of 308 patients undergone surgery. Chin Med J, 2008, 121(12):1080-1084.
- Shanghai Municipal Health Commission, ¥300,000, 2024ZZ2024
A multicenter clinical study of portable non-invasive DSPF for early diagnosis of intracranial hemorrhage
Role: Principal Investigator - Shanghai Jiao Tong University School of Medicine-Double Hundred Talents Program-Research Physicians, ¥1000,000, 20240819
A Randomized Controlled Clinical Study on Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care Patients
Role: Principal Investigator - National Natural Science Foundation of China, ¥550,000, 82071404
The role and mechanism of siPTEN-loaded nanoparticle targeting injury site to promote vascular repair after traumatic brain injury
Role: Principal Investigator - National Natural Science Foundation of China, ¥180,000, 81501657
The role and mechanism of PTEN ubiquitination in TBI induced microthrombosis formation via NF-κB signal pathway
Role: Principal Investigator
- [Hao Chen, Yunlei Wang, Lixia Xue, Kenan Wang, Shi Wang, Jiong Zhou] (2022), “An adjustable working channel for neuroendoscopic surgery”, PCT/ZL202220382891.1
- [Hao Chen, Lixia Xue, Jun Ding, Jiong Chen, Yuhui Cui, Fang Yuan] (2023), “A combination for reducing intracranial pressure and its usage method”, PCT/ZL202310334502.7
- [Hao Chen, Yunlei Wang, Kenan Wang, Shi Wang,] (2024), “An intracranial drainage catheter”, PCT/ZL202323631798.3
- [Hao Chen, Lixia Xue, Jiong Chen, Jiong Zhou] (2024), “An lumbar drainage system for intracranial pressure monitoring”, PCT/ZL202420108461.X
- [Hao Chen, Yuqing Liang, Lixia Xue, Lai Wei] (2025), “Method and application of nanoparticles targeting brain injury sites for the treatment of traumatic brain injury”, PCT/ZL202410187801.7
- [Hao Chen, Yunlei Wang, Lixia Xue, Kenan Wang, Shi Wang, Jiong Zhou] (2025), “An adjustable working channel for neuroendoscopic surgery”, PCT/ZL202210173774.9
