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CHEN Hao  

  • Chief Physician, Graduate Supervisor, Associate Professor
  • Department: Neurosurgery
  • Research Area: Surgery (Neurosurgery)
  • Research Interests: Basic and clinical research of traumatic brain injury, stroke and neurocritical care; artificial intelligence in neurosurgery
  • Contact: hao.chen@shsmu.edu.cn
Biography Positions Publications Patents
  • Doctoral Degree in Medicine from Shanghai Jiao Tong University School of Medicine, 2017
  • Master’s Degree from Shanghai Jiao Tong University Shcool of Medicine, 2008
  • Bachelor’s Degree in Clinical Medicine from Qingdao University School of Medicine, 2005                                                                    
  • Director, Department of Neurosurgery, Shanghai Sixth People's Hospital    
  • Shanghai Pujiang Talents
  • Visiting Assistant Professor of Vanderbilt University Medical Center
  • Committee Member of Peripheral Nerve Professional Committee of Chinese Medical Doctor Association (CMDA)  
  • Committee Member of the Neuroregeneration and Repair Professional Committee of the Chinese Research Hospital Association
  • Youth Committee Member of Trauma Branch of Shanghai Medical Association
  • Youth Committee Member of Neurosurgery Branch of Shanghai Medical Association
  • Member of American Congress of Neurological Surgeons (CNS)
  • Member of International Brain Injury Association (IBIA)
  1. Zhang S, Li S, Wang W#. Disu1.    Zhao J#, Shi Y#, Xue L, Liang Y, Shen J, Wang J, Wu M, Chen H*, Kong M*. Glucose-decorated engineering platelets for active and precise tumor-targeted drug delivery. Biomater Sci, 2023, 11(11):3965-3975. doi: 10.1039/d3bm00326d. 
  2. Xue LX#, Shu LY#, Wang HM, Lu KL, Huang LG, Xiang JY, Geng Z, Zhao YW, Chen H*. miR-181b promotes angiogenesis and neurological function recovery after ischemic stroke. Neural Regen Res, 2023, 18(9):1983-1989. doi: 10.4103/1673-5374.367957.
  3. Cai L#, Gong Q#, Qi L, Xu T, Suo Q, Li X, Wang W, Jing Y, Yang D, Xu Z, Yuan F, Tang Y, Yang G, Ding J*, Chen H*, Tian H*. ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway. Cell Commun Signal, 2022, 20:56. doi: 10.1186/s12964-022-00862-y.
  4. Chen H#, Gong Y, Ma Y, Thompson RC, Wang J, Cheng Z*, Xue L*. A Brain-Penetrating Hsp90 Inhibitor NXD30001 Inhibits Glioblastoma as a Monotherapy or in Combination With Radiation. Front Pharmacol, 2020, 11:974. doi: 10.3389/fphar.2020.00974. 
  5. Xue L#, Huang J, Zhang T, Wang X, Fu J, Geng Z, Zhao Y, Chen H*. PTEN inhibition enhances angiogenesis in an in vitro model of ischemic injury by promoting Akt phosphorylation and subsequent hypoxia inducible factor-1α upregulation. Metab Brain Dis, 2018, 33(5):1679-1688. doi: 10.1007/s11011-018-0276-5.
  6. Chen H#, Yuan F, Chen SW, Guo Y, Wang G, Deng ZF, Tian HL*. Predicting posttraumatic hydrocephalus: derivation and validation of a risk scoring system based on clinical characteristics. Metab Brain Dis, 2017, 32(5):1427-1435. doi: 10.1007/s11011-017-0008-2.
  7. Xue L#, Zhang T, Zhao Y, Geng Z, Chen J, Chen H*. Efficacy and safety comparison of DL 3 n butylphthalide and Cerebrolysin: Effects on neurological and behavioral outcomes in acute ischemic stroke. Exp Ther Med, 2016, 11(5):2015-2020. doi: 10.3892/etm.2016.3139.
  8. Chen H#, Cao H#, Chen S, Guo Y, Gao W, Tian H, Xue L*. Neuroglobin and Nogo-a as biomarkers for the severity and prognosis of traumatic brain injury. Biomarkers, 2015, 20(6-7):495-501. doi: 10.3109/1354750X.2015.1094138.                                                                                                                   
  9. Tian HL#, Guo Y, Hu J, Rong BY, Wang G, Gao WW, Chen SW, Chen H*. Clinical characterization of comatose patients with cervical spine injury and traumatic brain injury. J of Trauma, 2009, 67(6):1305-1310.17. doi: 10.1097/TA.0b013e31819db57c.                                                                                       
  10. Tian HL#, Geng Z, Cui YH, Hu J, Xu T, Cao HL, Chen SW, Chen H*. Risk factors for posttraumatic cerebral infarction in patients with moderate or severe head trauma. Neurosurg Rev, 2008, 31(4):431-437. doi: 10.1007/s10143-008-0153-5.
  1. [Hao Chen, Yunlei Wang, Lixia Xue, Kenan Wang, Shi Wang, Jiong Zhou] (2022), “An adjustable working channel for neuroendoscopic surgery”, PCT/CN218165299U, ZL202220382891.1
  2. [Hao Chen, Lixia Xue, Jun Ding, Jiong Chen, Yuhui Cui, Fang Yuan] (2023), “A combination for reducing intracranial pressure and its usage method”, PCT/CN116236547B; ZL202310334502.7         
  3.  [Lixia Xue, Hao Chen, Xiaojuan Cheng, Ligang Huang, Jiguo Yao, Jialu Tan, Jingjiong Chen] (2023), “A wearable epilepsy monitoring device”, PCT/CN202310450017.6 
  4. [Hao Chen, Yunlei Wang, Kenan Wang, Shi Wang,] (2023), “An intracranial drainage catheter”, PCT/CN2023236317983 
  5. [Hao Chen, Lixia Xue, Jiong Chen, Jiong Zhou] (2024), “An lumbar drainage system for intracranial pressure monitoring”, PCT/CN202420108461.X
  6. [Hao Chen, Yuqing Liang, Lixia Xue, Lai Wei] (2024), “A preparation method and application of nanoparticles targeting brain injury sites for the treatment of traumatic brain injury”, PCT/CN2024101878017

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