CAO Li  

  • Doctoral Supervisor, Professor
  • Department: Neurology
  • Research Area: Neurology
  • Research Interests: Neurogenetic diseases and movement disorders
  • Contact: caoli2015@126.com
  • Visiting Scholar in University of California, San Francisco, 2013
  • Ph.D. from Xiangya School of Medicine, Central South University, 2006
  • M.M. from Xiangya School of Medicine, Central South University, 2003
  • M.D. from Hunan Medical Univeristy, 1998
  1. Director, Department of Neurology, Shanghai Sixth People's Hospital_x000b_Vice Chairman, Group of Immunology, Genetics and Biochemistry, Division of Neurology, Shanghai Medical Association Member, Group of Neurogenetics, Division of Neurology, Chinese Medical Association Shanghai Outstanding Academic/Technical Leader (2023)
  2. Shanghai Health Leading Talents (2022) Member, Division of Neurologists, Shanghai Medical Doctor Association
  3. Member, Group of Neuromuscular Diseases, Division of Neurology, Shanghai Medical Association
  4. Secretary, Division of Rare Diseases of Shanghai Medical Doctor Association Member, China Rare Disease Alliance/Beijing Rare Disease Diagnosis, Treatment and Protection Society, Autoimmune Encephalitis Professional Committee
  5. Member, Division of Neurodegenerative Diseases, Chinese Neuroscience Institute
  6. Member, Chinese Stroke Society, Mobile Medical Branch Committee Member, China Rare Disease Alliance, Rare Neurological Diseases Professional Committee
  7. Member, Division of Rare Diseases, Chinese Research Hospital Institute Member, Shanghai Aging and Degenerative Diseases Association
  8. Member, Division of Neurology of Chinese Medical Care International Communication Promotion Association
  9. Member, Group of Neurogenetics, Division of Neurologists of Chinese Medical Doctor Association
  • 01/2024-12/2027
    National Natural Science Foundation of China, ¥490000, 82371255
    Study on the Role of GRID2IP in Neurotransmitter Signaling Pathways of Paroxysmal Kinesigenic Dyskinesia. _x005f Role: Principal Investigator
  • 12/2023-12/2024 
    Ministry of Education Industry-Academic Cooperation Collaborative Education Project, ¥50000, 230802999253547
    Health Management and Remote Assessment of Hereditary Ataxia. Role: Principal Investigator
  • 12/2023-11/2025
    Science and Technology Commission of Shanghai Municipality, ¥4700000, 23DZ2291500. 
    Shanghai Neurological Rare Disease Biobank and Precision Diagnostic Technical Service Platform (Shanghai Science and Technology Innovation Action Plan). 
    Role: Principal Investigator
  • 05/2023-04/2026
    Science and Technology Commission of Shanghai Municipality, ¥400000, 23XD1402500. 
    Cloning of Novel Genes and Mechanism Research in Paroxysmal Kinesigenic Dyskinesia (Program for Shanghai Outstanding Academic Leaders).
    Role: Principal Investigator
  • 01/2023-12/2025
    Shanghai Municipal Health Commission, ¥450000, 2022LJ011. 
    Study on Hematopoietic Stem Cell Transplantation Therapy and Biomarkers in CSF1R-Related Leukoencephalopathy (Program for Outstanding Medical Academic Leader of Shanghai).
    Role: Principal Investigator
  • 09/2022-12/2023
    Shanghai Jiao Tong University Medical and Engineering Interdisciplinary Project, ¥100000, 2022JK-LY23Y. 
    Development of PKD diagnosis and electrical stimulation rehabilitation system based on neural electrical signals.
    Role: Principal Investigator
  • 07/2022-09/2024
    Shanghai Hospital Development Center, ¥400000, SHDC2022CRD037. 
    Wearable Low-Frequency Pulsed Ultrasound Therapy for Paroxysmal Kinesigenic Dyskinesia (Training Program for research
    physicians of innovative translational ability).
    Role: Principal Investigator
  • 01/2022-12/2024
    Shanghai Charity Foundation, ¥475000, 2022-01. 
    Gene Therapy for Hereditary Spastic Paraplegia Type 11.
    Role: Principal Investigator
  • 01/2021-12/2023
    Sixth People’s Hospital affiliated to Shanghai Jiao Tong University, ¥150000, /. 
    PolyG-Notch2nlc Transgenic Mouse Model.
    Role: Principal Investigator
  • 01/2021-12/2023
    Shanghai Rare Disease Prevention Foundation, ¥1000000, 2021-43. 
    Study on Gene Therapy of Hereditary Spastic Paraplegia Type 35
    Role: Principal Investigator
  • 01/2021-12/2024
     National Natural Science Foundation of China, ¥550000, 82071258. 
    Hereditary Diffuse Leukoencephalopathy with Spheroids; Colony-Stimulating Factor-1 Receptor; Bone Marrow Transplantation.
    Role: Principal Investigator
  • 01/2019-12/2022
    National Natural Science Foundation of China, ¥560000, 81870889. 
    Study on the Role of GRID2IP in Neurotransmitter Signaling Pathways of Paroxysmal Kinesigenic Dyskinesia.
    Role: Principal Investigator
  • 07/2017-12/2020
    National Key Research and Development Program, ¥330000, 2017YFC1310200: 2017YFC1310201,2017YFC1310202, 2017YFC1310203,2017YFC1310204. 
    Research on New Treatment Methods and Techniques for Parkinson's Disease.
    Role: Project Participant
  • 01/2017-12/2019
    Medical-Industrial Cross-Research Fund Project of Shanghai Jiao Tong University, ¥210000, YG2016MS64. 
    Development of the Assisted Rehabilitation Robot for Spastic Paraplegia.
    Role: Principal Investigator
  • 07/2016-06/2019
    Research Physicians Project of Shanghai Jiao Tong University School of Medicine, ¥1000000, 20161401. 
    Multi-Center Study of Paroxysmal Kinesigenic Dyskinesia. 
    Role: Principal Investigator
  • 01/2016-12/2019
    National Natural Science Foundation of China, ¥570000, 81571086. 
    The Role of Neurotransmitter Release in the Pathogenesis of PRRT2 Related Diseases. 
    Role: Principal Investigator
  • 01/2013-12/2026
    National Natural Science Foundation of China, ¥700000, 81271262. 
    Study on the Role of 27-hydroxycholesterol and dehydroepiandrosterone sulfate in the pathogenesis of SPG5A.
    Role: Principal Investigator
  • 07/2012-06/2016
    Shanghai Natural Science Foundation, ¥100000. Pathogenic Mechanisms of PRRT2 Mutations in Paroxysmal Movement-Induced Disorders.
    Role: Principal Investigator
  • 01/2008-12/2010
    National Natural Science Foundation of China, ¥170000, 30700888. 
    The Mechanism of Anti-Oxidative Stress of DJ-1 Mediated by DJ-1 through PI3K/Akt Signaling Pathway.
    Role: Principal Investigator