Visiting Scholar in University of California, San Francisco, 2013
Ph.D. from Xiangya School of Medicine, Central South University, 2006
M.M. from Xiangya School of Medicine, Central South University, 2003
M.D. from Hunan Medical Univeristy, 1998
Director, Department of Neurology, Shanghai Sixth People's Hospital_x000b_Vice Chairman, Group of Immunology, Genetics and Biochemistry, Division of Neurology, Shanghai Medical AssociationMember, Group of Neurogenetics, Division of Neurology, Chinese Medical Association Shanghai Outstanding Academic/Technical Leader (2023)
Shanghai Health Leading Talents (2022)Member, Division of Neurologists, Shanghai Medical Doctor Association
Member, Group of Neuromuscular Diseases, Division of Neurology, Shanghai Medical Association
Secretary, Division of Rare Diseases of Shanghai Medical Doctor AssociationMember, China Rare Disease Alliance/Beijing Rare Disease Diagnosis, Treatment and Protection Society, Autoimmune Encephalitis Professional Committee
Member, Division of Neurodegenerative Diseases, Chinese Neuroscience Institute
Member, Chinese Stroke Society, Mobile Medical Branch CommitteeMember, China Rare Disease Alliance, Rare Neurological Diseases Professional Committee
Member, Division of Rare Diseases, Chinese Research Hospital InstituteMember, Shanghai Aging and Degenerative Diseases Association
Member, Division of Neurology of Chinese Medical Care International Communication Promotion Association
Member, Group of Neurogenetics, Division of Neurologists of Chinese Medical Doctor Association
01/2024-12/2027
National Natural Science Foundation of China, ¥490000, 82371255
Study on the Role of GRID2IP in Neurotransmitter Signaling Pathways of Paroxysmal Kinesigenic Dyskinesia. _x005fRole: Principal Investigator
12/2023-12/2024
Ministry of Education Industry-Academic Cooperation Collaborative Education Project, ¥50000, 230802999253547
Health Management and Remote Assessment of Hereditary Ataxia.Role: Principal Investigator
12/2023-11/2025
Science and Technology Commission of Shanghai Municipality, ¥4700000, 23DZ2291500.
Shanghai Neurological Rare Disease Biobank and Precision Diagnostic Technical Service Platform (Shanghai Science and Technology Innovation Action Plan).
Role: Principal Investigator
05/2023-04/2026
Science and Technology Commission of Shanghai Municipality, ¥400000, 23XD1402500.
Cloning of Novel Genes and Mechanism Research in Paroxysmal Kinesigenic Dyskinesia (Program for Shanghai Outstanding Academic Leaders).
Role: Principal Investigator
01/2023-12/2025
Shanghai Municipal Health Commission, ¥450000, 2022LJ011.
Study on Hematopoietic Stem Cell Transplantation Therapy and Biomarkers in CSF1R-Related Leukoencephalopathy (Program for Outstanding Medical Academic Leader of Shanghai).
Role: Principal Investigator
09/2022-12/2023
Shanghai Jiao Tong University Medical and Engineering Interdisciplinary Project, ¥100000, 2022JK-LY23Y.
Development of PKD diagnosis and electrical stimulation rehabilitation system based on neural electrical signals.
Role: Principal Investigator
07/2022-09/2024
Shanghai Hospital Development Center, ¥400000, SHDC2022CRD037.
Wearable Low-Frequency Pulsed Ultrasound Therapy for Paroxysmal Kinesigenic Dyskinesia (Training Program for research
physicians of innovative translational ability).
Role: Principal Investigator
01/2022-12/2024
Shanghai Charity Foundation, ¥475000, 2022-01.
Gene Therapy for Hereditary Spastic Paraplegia Type 11.
Role: Principal Investigator
01/2021-12/2023
Sixth People’s Hospital affiliated to Shanghai Jiao Tong University, ¥150000, /.
PolyG-Notch2nlc Transgenic Mouse Model.
Role: Principal Investigator
01/2021-12/2023
Shanghai Rare Disease Prevention Foundation, ¥1000000, 2021-43.
Study on Gene Therapy of Hereditary Spastic Paraplegia Type 35
Role: Principal Investigator
01/2021-12/2024
National Natural Science Foundation of China, ¥550000, 82071258.
Hereditary Diffuse Leukoencephalopathy with Spheroids; Colony-Stimulating Factor-1 Receptor; Bone Marrow Transplantation.
Role: Principal Investigator
01/2019-12/2022
National Natural Science Foundation of China, ¥560000, 81870889.
Study on the Role of GRID2IP in Neurotransmitter Signaling Pathways of Paroxysmal Kinesigenic Dyskinesia.
Role: Principal Investigator
07/2017-12/2020
National Key Research and Development Program, ¥330000, 2017YFC1310200: 2017YFC1310201,2017YFC1310202, 2017YFC1310203,2017YFC1310204.
Research on New Treatment Methods and Techniques for Parkinson's Disease.
Role: Project Participant
01/2017-12/2019
Medical-Industrial Cross-Research Fund Project of Shanghai Jiao Tong University, ¥210000, YG2016MS64.
Development of the Assisted Rehabilitation Robot for Spastic Paraplegia.
Role: Principal Investigator
07/2016-06/2019
Research Physicians Project of Shanghai Jiao Tong University School of Medicine, ¥1000000, 20161401.
Multi-Center Study of Paroxysmal Kinesigenic Dyskinesia.
Role: Principal Investigator
01/2016-12/2019
National Natural Science Foundation of China, ¥570000, 81571086.
The Role of Neurotransmitter Release in the Pathogenesis of PRRT2 Related Diseases.
Role: Principal Investigator
01/2013-12/2026
National Natural Science Foundation of China, ¥700000, 81271262.
Study on the Role of 27-hydroxycholesterol and dehydroepiandrosterone sulfate in the pathogenesis of SPG5A.
Role: Principal Investigator
07/2012-06/2016
Shanghai Natural Science Foundation, ¥100000. Pathogenic Mechanisms of PRRT2 Mutations in Paroxysmal Movement-Induced Disorders.
Role: Principal Investigator
01/2008-12/2010
National Natural Science Foundation of China, ¥170000, 30700888.
The Mechanism of Anti-Oxidative Stress of DJ-1 Mediated by DJ-1 through PI3K/Akt Signaling Pathway.
Role: Principal Investigator