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CAI Xiaojun
- Doctoral Supervisor, Researcher
- Department: Ultrasound in Medicine
- Research Area: Imaging and Nuclear Medicine (Ultrasound)
- Research Interests: Single cell atlas of Prussian blue in tissue and organ regeneration and repair
- Contact: caixiaojun00@sjtu.edu.cn
- Fellowship, Shanghai Jiao Tong University School of Medicine, 2017
- PhD from Shanghai Institute of Ceramics, Chinese Academy of Science, 2017
- Chenyi Ye†, Wei Zhang†, Yongzheng Zhao†, Kai Zhang, Weiduo Hou, Mo Chen, Jinwei Lu, Jianrong Wu, Rongxin He*, Wei Gao*, Yuanyi Zheng, Xiaojun Cai*. Prussian Blue Nanozyme Normalizes Microenvironment to Delay Osteoporosis, Advanced Healthcare Materials, 2022, 2200787.
- Rui Hou#, Tianxiang Lu#, Wei Gao*, Jian Shen, Zheyuan Yu, Datao Li, Ruhong Zhang*, Yuanyi Zheng, Xiaojun Cai*. Prussian blue nanozyme promotes the survival rate of skin flap by maintaining normal microenvironment, ACS Nano, 2022, 16, 6, 9559–9571.
- Xinxin Ma, Junnian Hao, Jianrong Wu, Yuehua Li, Xiaojun Cai*, Yuanyi Zheng*, Prussian blue nanozyme as a pyroptosis inhibitor alleviates neurodegeneration, Advanced Materials, 2022, 34(15), 2106723.
- Weiduo Hou#, Chenyi Ye#, Mo Chen#, Wei Gao, Xue Xie, Jianrong Wu, Kai Zhang, Wei Zhang*, Yuanyi Zheng*, Xiaojun Cai*, Excavating bioactivities of nanozyme to remodel microenvironment for protecting chondrocytes and delaying osteoarthritis, Bioactive Materials，2021，6, 2439–2451
- Xue Xie#, Jiulong Zhao#, Wei Gao#, Jie Chen*, Bing Hu, Xiaojun Cai*, Yuanyi Zheng*. Prussian blue nanozyme-mediated nanoscavenger ameliorates acute pancreatitis via inhibiting TLRs/NF-κB signaling pathway, Theranostics 2021; 11(7):3213-3228.
- Lishuai Feng#, Chaoran Dou#, Yuguo Xia#, Benhao Li, Mengyao Zhao, Peng Yu, Yuanyi Zheng, Ahmed Mohamed El-Toni, Nada Farouk Atta, Ahmed Galal, Yingsheng Cheng*, Xiaojun Cai*, Yan Wang*, and Fan Zhang*. Neutrophil-like Cell-Membrane-Coated Nanozyme Therapy for Ischemic Brain Damage and Long-Term Neurological Functional Recovery. ACS Nano，2021, 15(2), 2263–2280
- Lishuai Feng#, Chaoran Dou#, Yuguo Xia#, Benhao Li, Mengyao Zhao, Ahmed Mohamed El-Toni, Nada Farouk Atta, Yuanyi, Zheng, Xiaojun Cai*, Yan Wang*, Yingsheng Cheng*, Fan Zhang*, Enhancement of Nanozyme Permeation by Endovascular Interventional Treatment to Prevent Vascular Restenosis via Macrophage Polarization Modulation. Advanced Functional Materials. 2020, 30(52), 2006581.
- Kai Zhang, Mengjiao Tu, Wei Gao, Xiaojun Cai*, Fahuan Song, Zheng Chen, Qian Zhang, Jing Wang, Chentao Jin, Jingjing Shi, Xiang Yang, Yuankai Zhu, Weizhong Gu, Bing Hu, Yuanyi Zheng*, Hong Zhang*, and Mei Tian*, Hollow Prussian Blue Nanozymes Drive Neuroprotection against Ischemic Stroke via Attenuating Oxidative Stress, Counteracting Inflammation, and Suppressing Cell Apoptosis, Nano Letters, 2019, 19(5):2812-2823
- Jiulong Zhao#, Wei Gao#, Xiaojun Cai*, Jiajia Xu, Duowu Zou*, Zhaoshen Li, Bing Hu*, Yuanyi Zheng*, Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease, Theranostics, 2019, 9(10):2843-2855
- Jiulong Zhao, Xiaojun Cai*, Wei Gao, Linlin Zhang, Duowu Zou, Yuanyi Zheng, Zhaoshen Li*, and Hangrong Chen*，Prussian Blue Nanozyme with Multi-enzyme Activity Reduces Colitis in Mice. ACS Appl. Mater. Interfaces, 2018, 10(31), 26108–26117
- 01/01/2022-12/31/2025
National Natural Science Foundation of China General Project, ¥550,000, 82172074
Mechanism of nanozyme-enhanced high intensity focused ultrasound-mediated sonodynamic therapy and thermal ablation for treating pancreatic cancer
Role: Principal Investigator - 01/11/2023-10/31/2027
National Key Research and Development Project, ¥700,000, 2023YFC2411704
Preclinical animal research and validation of multispectral functional imaging
Role: Project leader
