AI Zhihong  

  • Chief Physician, Graduate Supervisor
  • Department: Gynaecology and Obstetrics
  • Research Area: Gynaecology and Obstetrics
  • Research Interests: Pathogenesis of ovarian cancer, endometrial cancer, and cervical cancer
  • Contact: ai_zhihong@126.com
  • Visiting Scholar at MD Anderson Cancer Center in the United States, 2013
  • PhD in Obstetrics and Gynecology from Fudan University, 2006
  • Master's degree in Obstetrics and Gynecology from Harbin Medical University, 2002
  • Chief Physician, Department of Gynaecology and Obstetrics, Shanghai Sixth People's Hospital
  1. Lan Lin, Xiao Li, Ai-Jia Wu, Jia-Bin Xiu, Yu-Zheng Gan, Xiao-Mei Yang#, Zhi-Hong Ai#. TRPV4 enhances the synthesis of fatty acids to drive the progression of ovarian cancer through the calcium-mTORC1/SREBP1 signaling pathway. iScience, 2023 Oct 18;26(11):108226. doi:10.1016/j.isci.2023.108226. eCollection 2023 Nov 17.
  2. Aijia Wu, Lan Lin, Xiao Li, Qinyang Xu, Wei Xu, Xiaolu Zhu, Yincheng Teng, Xiao-Mei Yang#, Zhihong Ai#. Overexpression of ARHGAP30 suppresses growth of cervical cancer cells by downregulating ribosome biogenesis. Cancer Science, 2021 Nov, 112(11):4515-4525. doi: 10.1111/cas.15130. Epub 2021 Sep 21.
  3. Juan Wang, Aijia Wu, Bingqing Yang, Xiaolu Zhu, Yincheng Teng, Zhihong Ai#. Profiling and bioinformatics analyses reveal differential circular RNA expression in ovarian cancer. Gene,2020, Jan 15; 724: 144150. doi: 10.1016/j.gene.2019.144150. Epub 2019 Oct 4.
  4. Bao-hua Yang,Ming-xia Yu,Jun Xu,Yan Su,Zhi-hong Ai#. The Value of DNA Quantitative Cytology Test for the Screening of Endometrial Cancer. Cancer Manag Res,2019 Dec 11; 11: 10383-10391. doi: 10.2147/CMAR.S225672. eCollection 2019.
  5. Qinyang Xu, Qin Yang, Yang Zhou, Bikang Yang, Rongzhen Jiang, Zhihong Ai#, Yincheng Teng#. A long noncoding RNAs signature to improve survival prediction in endometrioid endometrial cancer. J Cell Biochem, 2019 May; 120(5): 8300-8310. doi: 10.1002/jcb.28113. Epub 2018 Dec 11.
  6. Zhihong Ai, Yang Lu, Songbo Qiu, Zhen Fan#. Overcoming cisplatin resistance of ovarian cancer cells by targeting HIF-1-regulated cancer metabolism. Cancer Letter,2016 Apr 1; 373(1): 36-44. doi: 10.1016/j.canlet.2016.01.009. Epub 2016 Jan 19.
  7. Zhihong Ai, Juan Wang, Yanli Xu,Yincheng Teng#. Bioinformatics analysis reveals potential candidate drugs for cervical cancer. J Obstet Gynaecol Res, 2013 May; 39(5): 1052-1058. doi: 10.1111/jog.12022. Epub 2013 Apr 4.
  8. Zhihong Ai, Juan Wang, Yudong Wang, Lihua Lu, Jianqian Tong, Yincheng Teng#. Overexpressed epidermal growth factor receptor (EGFR)-induced progestin insensitivity in human endometrial carcinoma cells by the EGFR/mitogen-activated protein kinase signaling pathway. Cancer. 2010 Aug 1; 116(15): 3603-3613. doi: 10.1002/cncr.25220.
  9. Zhihong Ai, Lianhua Yin, Xianrong Zhou, Ying Zhu, Dongmei Zhu, Yinhua Yu, Youji Feng#. Inhibition of survivin reduces cell proliferation and induces apoptosis in human endometrial cancer. Cancer. 2006 Aug 15; 107(4): 746-756. doi: 10.1002/cncr.22044.