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DU Wenxian
- Graduate Supervisor, Associate Researcher
- Department: Radiology
- Research Area: Molecular Imaging
- Research Interests: Drug delivery system for visualizing the treatment of cardiovascular and cerebrovascular diseases
- Contact: wx0910@mail.ustc.edu.cn
- Associate Researcher, Shanghai Sixth People’s Hospital, 2023
- Assistant Researcher, Shanghai Sixth People’s Hospital, 2020
- PhD from Shanghai Institute of Ceramics, Chinese Academy of Sciences, 2020
- MPH from Shanghai Institute of Ceramics, Chinese Academy of Sciences, 2017
- Youth Editorial Board Member, Exploration, View, Biomaterials Translational, Medical Materials Research
- Secretary, Shanghai Young Science and Technology Talents Association
- Sun, Yuxiang, Cao, Ziqi, Zhang, Xiaoli, Zhu, Xingchen, Xu, Zhenyang, Zhou, Hantong, Wei, Xiaoer,* Du, Wenxian,* Xu, Li*, Rod-Shaped Au@Ce Nano-Platforms for Enhancing Photodynamic Tumor Collaborative Therapy. Small Methods 2024, 2400945
- Zhang, Qiang†; Liu, Zihao†; Li, Bo*; Sheng, Kai; Xiong, Yijia; Cheng, Jiahui; Zhou, Jia; Xiong, Zhi; Jiang, Lixian; Wu, Jianrong; Cai, Xiaojun; Zheng, Yuanyi; Du, Wenxian*; Li, Yuehua*; Zhu, Yueqi*. Platinum-loaded Cerium Oxide Capable of Repairing Neuronal Homeostasis for Cerebral Ischemia-Reperfusion Injury therapy. Advanced Healthcare Materials 2024，2023027
- Sun, Yuxiang*; Xu, Tianze; Qian, Yike; Chen, Qiaoyun; Xiong Fei; Du, Wenxian*; Xu Li*. NOS-like Activity of CeO2 Nanozymes Contributes to Diminishing the Vascular Plaques. Journal of Nanobiotechnology 2024, 22,12
- Li, Bo†; Zhang, Qiang†; Du, Wenxian*; Wu, Jianrong; Cheng, Jiahui; Zhang, Yiming; Gao, Rifeng; Zhao, Xinxin; Jiang, Lixian; Wu, Yingming; Cai, Xiaojun; Zheng, Yuanyi; Li, Yuehua*; Zhou, Yan*, Reshaping cardiac microenvironments by macrophage-derived extracellular vesiclescoated Pd@CeO2 heterostructures for myocardial ischemia/reperfusion injury therapy. Materials Today 2023, 03, 024: 47-61.
- Du, Wenxian; Wang, Jienan; Zhou, Lingling; Zhou, Jia; Feng, Lishuai; Dou, Chaoran; Zhang, Qiang; Zhang, Xiaoxing; Zhao, Qianqian; Cai, Xiaojun; Wu, Jianrong; Zheng, Yuanyi; Li, Yuehua, Transferrin-targeted iridium nanoagglomerates with multi-enzyme activities for cerebral ischemia-reperfusion injury therapy. Acta Biomaterialia 2023, 04, 025.
- Zou, Weijuan†; Wang, Longchen†; Hao, Junnian; Jiang, Lixian; Du, Wenxian*; Ying, Tao; Cai, Xiaojun; Ran, Haitao; Wu, Jianrong*; Zheng, Yuanyi*, Phase-Change Cascaded Nanomedicine for Intensive Photothermal Enhanced Nanocatalytic Therapy via Tumor Oxidative Stress Amplification. Composites Part B: Engineering 2022, 234, 109707.
- Zhao, Qianqian†; Du, Wenxian†; Zhou Lingling; Wu Jianrong; Zhang Xiaoxing; Jiang Jingxuan; Wei Xiaoer; Wang Sijia; Huang Yu; Cai Xiaojun; Zheng Yuanyi; Li Yuehua*. Transferrin-Enabled Blood-Brain Barrier Crossing Manganese- Based Nanozyme for Rebalancing the Reactive Oxygen Species Level in Ischemic Stroke. Pharmaceutics 2022, 14, 1122.
- Du, Wenxian; Zhou, L.; Zhang, Q.; Liu, X.; Wei, X.; Li, Y., Inorganic Nanomaterial for Biomedical Imaging of Brain Diseases. Molecules 2021, 26, 7340.
- Du, Wenxian; Liu, T.; Xue, F.; Chen, Y.; Chen, Q.; Luo, Y.; Cai, X.; Ma, M.; Chen, H., Confined Nanoparticles Growth within Hollow Mesoporous Nanoreactors for Highly Efficient MRI-guided Photodynamic Therapy. Chemical Engineering Journal 2020, 379, 122251.
- Du, Wenxian; Liu, Tianzhi*; Xue, Fengfeng; Cai, Xiaojun; Chen, Qian; Zheng, Yuanyi; Chen, Hangrong*, Fe3O4 Mesocrystalswith Distinctive Magnetothermal and Nano-Enzyme Activity Enabling Self-Reinforcing Synergistic Cancer Therapy. ACS Applied Materials & Interfaces 2020, 12, 19285-19294.
- 01/01/2025-12/31/2027
National Natural Science Foundation of China, ¥300,000, 32401157
Biomimetic nanozyme-mediated lactate metabolism visualization and targeted therapy for stroke and its mechanisms research
Role: Principal Investigator - 04/01/2021-3/31/2024
Shanghai Sailing Program, ¥200,000, 21YF1434100
Design and synthesis of exosomal biomimetic nanomedicines and their ferroptosis mechanism in breast cancer
Role: Principal Investigator - 11/01/2020-11/31/2023
Shanghai Sixth People's Hospital Scientific Research Fund Project, ¥250,000
Research on the Treatment of Cerebral Ischemia Reperfusion Injury with Nano-Cerium Oxide-Loaded Platinum Clusters
Role: Principal Investigator - 06/01/2021-6/01/2024
Shanghai Sixth People's Hospital Basic Research Project Youth Cultivation, ¥100,000, ynqn202109
IrO2@Tf-Eda Nanozyme Targeted Across the Blood-Brain Barrier Visualization Treatment of Stroke
Role: Principal Investigator
- [Xiaojun Cai, Wenxian Du, Ning Wang, Hangrong Chen, Jianlin Shi] (2018), “Nano-diagnostic agent based on Prussian blue analogue, preparation method and application thereof”, CN 106581057 B
- [Yuehua Li, Wenxian Du, Qiang Zhang, Jia Zhou, Yingming Wu] (2024), “Preparation method of multi-enzyme active platinum-loaded cerium oxide nanozyme, and its products and applications”, 2024106466013
