CHEN Dafan  

  • Associate Chief Physician, Graduate Supervisor
  • Department: Gastroenterology
  • Research Area: Inflammatory bowel disease
  • Research Interests: Immunological pathogenesis of intestinal Injury
  • Contact: chendafan595@163.com
  • PhD in Internal Medicine from Shanghai Jiao Tong University School of Medicine, 2010
  • MD in Internal Medicine from Fujian Medical University, 2007                                        
  • Bachelor's Degree in Clinical Medicine from Fujian Medical University, 2000
  • Member of the Digestive Disease Equipment and Technology Branch of the Chinese Association for Medical Equipment                                                                                                                  
  • Member of the Digestive Endoscopy Professional Committee of Shanghai Anti-Cancer Association
  • Young member of the Digestive Endoscopy Specialty Branch of Shanghai Medical Association 
  • Member of the Inflammatory Bowel Disease Group of the Digestive System Disease Branch of Shanghai Medical Association
  1. Chen D#, Ren Y, Chen S, Jin Y, Xie H, Yu L, Peng K, Xia Y, Pan D, Lu J, Lu L, Wan X, Hu D, Li B. The Wet Suction Technique Enhances the Diagnostic Efficacy and Aspirate Quality of EUS-FNA for Solid Lesions: A Multicenter Retrospective Study in China. J Clin Gastroenterol. 2023;57:417-422. doi: 10.1097/MCG.0000000000001700.
  2. Li Y, Yang Y, Chen D#, Wang Y, Zhang X, Li W, Chen S, Wong SM, Shen M, Akerley BJ, Shen H. Memory Th17 cell-mediated protection against lethal secondary pneumococcal pneumonia following influenza infection. mBio. 2023 Aug 31;14(4):e0051923. doi: 10.1128/mbio.00519-23.
  3. Chen D#, Ning M, Feng Y, Liu J. The early stage of COVID-19 pandemic: Gastrointestinal manifestations and liver injury in COVID-19 patients in Wuhan, China. Front Med (Lausanne). 2022 Oct 20;9:997000. doi: 10.3389/fmed.2022.997000.
  4. Xiao H, Zhang Y, Li Z, Liu B, Cui D, Liu F, Chen D#, Liu Y, Ouyang G. Periostin deficiency reduces diethylnitrosamine-induced liver cancer in mice by decreasing hepatic stellate cell activation and cancer cell proliferation. J Pathol. 2021 Oct;255(2):212-223. doi: 10.1002/path.5756.
  5. Chen D#, Ma J, Ben Q, Lu L, Wan X. Prior Appendectomy and the Onset and Course of Crohn's Disease in Chinese Patients. Gastroenterol Res Pract. 2019 Jul 17; 2019:8463926. doi: 10.1155/2019/8463926.
  6. Chen D#, Ma J, Luo S, Lu L, Wan X, Ben Q. Effects of Appendectomy on the Onset and Course of Ulcerative Colitis in Chinese Patients. Gastroenterol Res Pract. 2018 Nov 6; 2018:2927891. doi: 10.1155/2018/2927891.
  7. Chen D#, Luo S, Ben Q, Lu L, Wan X, Wu J. Prevalence of hepatitis B and C and factors for infection and nonimmune in inflammatory bowel disease patients in China. Eur J Gastroenterol Hepatol. 2017 May;29(5):509-515. doi: 10.1097/MEG.0000000000000838.
  8. Chen DF#, Lu LG, Tao KZ, Lu ZJ, Yuan YZ. Recovery from TNBS-induced colitis leads to the resistance to recurrent colitis and an increased ratio of FOXP3 to CD3 mRNA. J Dig Dis. 2013 Nov;14(11):587-595. doi: 10.1111/1751-2980.12084.
  9. Chen DF#, Gong BD, Xie Q, Ben QW, Liu J, Yuan YZ. MicroRNA155 is induced in activated CD4(+) T cells of TNBS-induced colitis in mice. World J Gastroenterol. 2010 Feb 21;16(7):854-61. doi: 10.3748/wjg.v16.i7.854.
  • 11/01/2023-10/31/2026
    Institutional Research Project of Shanghai Sixth People's Hospital, ¥100,000
    Exploring the Mechanisms of Small Intestinal Injury Induced by Pneumococcal Pneumonia Based on the "Lung-Gut Axis"
    Role: Principal Investigator
  • 12/01/2023-11/30/2026
    Medical Innovation Research Special Project of Science and Technology Commission of Shanghai Municipality, ¥300,000
    Efficacy and Safety of Early Drainage for Severe Acute Pancreatitis with Peripancreatic Fluid Collections: A Prospective, Multicenter, Randomized Controlled Trial
    Role: Sub-Center Principal Investigator