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CAO Yiyun
- Graduate Supervisor, Professor
- Department: Anesthesiology
- Research Area: Anesthesiology
- Research Interests: Perioperative cardiovascular and cerebrovascular protection, pharmacology for anesthesia
- Contact: sublimate66@126.com
- MD from Peking University School of Medicine, 2016
- MPH from Ningxia Medical University, 2008
- Physician, Department of Anesthesiology, Shanghai Sixth People's Hospital.
- Xinning Mi#, Yiyun Cao#, Yue Li, Yitong Li, Jingshu Hong, Jindan He,
Yaoxian Liang, Ning Yang, Taotao Liu, Dengyang Han, Chongshen Kuang, Yongzheng Han, Yang Zhou, Yajie Liu, Chengmei Shi, Guo Xiangyang*, Zhengqian Li*. The non-peptide angiotensin-(1-7) mimic AVE attenuates delayed neurocognitive recovery after laparotomy by reducing neuroinflammation and restoring blood-brain barrier integrity in aged rats. Frionters in Aging Neuroscicence. 2021; 2(15): 624387.doi: 10.3389/fnagi.2021.624387. - Yiyun Cao#, Taotao Liu#, Zhengqian Li, Jiao Yang, Lijun Ma, Xinning Mi, Ning Yang, Aihua Qi, Xiangyang Guo*, Aizhong Wang*. Neurofilament degradation is involved in laparotomy-induced cognitive dysfunction in aged rats. Aging. 2020; 12(24): 25643–25657.doi:10.18632/aging.104172.
- Yiyun Cao, Zhengqian Li, Hongping Li, Cheng Ni, Lunxu Li, Ning Yang,Chengmei Shi, Yanfeng Zhong*, Dehua Cui*, Xiangyang Guo*. Hypoxia-inducible factor-1α isinvolved in isoflurane-induced blood-brain barrier disruption in aged rats model of POCD.Behavioural Brain Research. 2018; 339: 39-46.1. 2017,doi:10.1016/j.bbr.2017.09.004.
- Cao, Zhengqian Li, Lijun Ma, Ning Yang, Xiangyang Guo*.Isoflurane-induced postoperative neurovascular and cognitive dysfunction is associated with VEGF overexpression in aged rats. Journal of Molecular Neuroscience. 2019; 11(18): 1350-1358.doi: 10.1007/s12031-019-01350-8.
- Yiyun Cao, Zhengqian Li, LijunMa, ChengNi, Lunxu Li, YangNi, ChengmeiShi, Xiangyang Guo*. Isoflurane-induced postoperative cognitive dysfunction is mediated by hypoxia-inducible factor-1α-dependent neuroinflammation in aged rats. Molecular Medicine Report. 2018; 17(6): 7730-7736.doi:10.3892/mmr.2018.8850.
- Yiyun Cao, Cheng Ni, Zhengqian Li, Lunxu Li, Yajie Liu, Chunyi Wang, Yanfeng Zhong*, Dehua Cui*, Xiangyang Guo*. Isoflurane anesthesia results in reversible ultrastructure and occludin tight junction protein expression changes in hippocampal blood-brain barrier in aged rats. Neuroscience Letter. 2015; 587:51-56.doi: 10.1016/j.neulet.2014.12.018.
- 01/01/2019-12/31/2022
Shanghai Pudong New Area Science and Technology Development Fund livelihood research special (medical and health project) , ¥360,000, PKJ2018-Y56,
Systematic characterizations of subject design, quality control, paper writing.
Role: Principal Investigator
