LU YI  

  • Graduate Supervisor, Researcher
  • Department: Respiratory Medicine
  • Research Area: Internal medicine
  • Research Interests: Pathogenesis of pulmonary fibrosis
  • Contact: luyi0718@126.com
  • Researcher, Mayo Clinic, Biochemistry and Molecular Biology, 2019
  • MD from Second Military Medical University, 2010
  • PhD from Shanghai Jiao Tong University, 2021
  • Vice Director, Department of Respiratory Medicine, Shanghai Sixth People's Hospital
  • Committee Member, Shanghai Medical Doctor Association Respiratory Branch 
  • Youth Committee Member, Shanghai Medical Association Respiratory Branch
  1. Lu Yi; Liu Zeyu; Zhang Yunjiao; Wu Xiuhua; Bian Wei; Shan Shan; Yang Danrong; Ren Tao ; METTL3-mediated m6A RNA methylation induces the differentiation of lung resident mesenchymal stem cells into myofibroblasts via the miR-21/PTEN pathway, Respiratory Research, 2023, 24(1): 300(1)-300(16) 
  2. Tian Guangliang; Shi Yihan; Deng Jixia; Yu Wenhua; Yang Leihang; Lu Yi; Zhao Yi; Jin Xiangyu; Ke Qinfei; Huang Chen ; Low-Cost, Scalable Fabrication of All-Fabric Piezoresistive Sensors via Binder-Free, In-Situ Welding of Carbon Nanotubes on Bicomponent Nonwovens, Advanced Fiber Materials, 2023.https://doi.org/10.1007/s42765-023-00331-2 
  3. Ru Hu; Lei Wang; Shuaiwen Xu; Yi Lu; Shenghu Zhou ; Silica nanospheres-encapsulated polymer ligands-bound Pd nanoparticles as highly efficient and selective catalysts for semi-hydrogenations of alkynes, Microporous and Mesoporous Materials, 2024, 377 (2024) 113213 https://doi.org/10.1016/j.micromeso.2024.113213
  4. Lu Yi; Zhang Tiefeng; Shan Shan; Wang Shenqi; Bian Wei; Ren Tao; Yang Danrong ; MiR-124 regulates transforming growth factor-β1 induced differentiation of lung resident mesenchymal stem cells to myofibroblast by repressing Wnt/β-catenin signaling, Developmental Biology, 2019, 449(2): 115-121 
  5. Wang Yujia; Lu Yi; Wu Yingchuan; Sun Yufen; Zhou Yueqing; Ma Qiwang; Zheng Yawen; Yu Qianwen; Cao Yujie; Chen Guangdong; Zhang Ting; Dai Xiaotian; Ren Tao; Ma Yu; Zuo Wei ; Alveolar Differentiation Potency of Human Distal Airway Stem Cells Is Associated with Pulmonary Pathological Conditions, Stem Cells International, 2019, 2019: 7123078(1)-7123078(11)
  6. Lu Yi; Li Zhenjie; Xie Baoqiang; Song Yan; Ye Xiaoqing; Liu Pingping ; hsa-miR-20a-5p attenuates allergic inflammation in HMC-1 cells by targeting HDAC4, Molecular Immunology, 2019, 107: 84-90
  • 01/01/2025-12/31/2028
    National Natural Science Foundation of China (General Program), ¥490,000, 82471627
    Disorder of pyruvate metabolism induces the senescence of LR-MSCs and facilitates the progress of Idiopathic Pulmonary Fibrosis via modulating liquid-liquid phase separation of YTHDF2.
    Role: Principal Investigator
  • 01/01/2021-12/31/2023
    National Natural Science Foundation of China (Youth Program), ¥240,000, 82000067
    Role and Mechanism of Primary Cilia damage in Lung resident Mesenchymal stem cells differentiation in IPF.
    Role: Principal Investigator
  • 08/01/2024-07/31/2027
    Shanghai Sixth People's Hospital General Cultivation Project, ¥300,000, ynms202409
    Mechanism of MPC1 regulating m6A modified landscapes in LR MSCs through YTHDF2 and participating in idiopathic pulmonary fibrosis.
    Role: Principal Investigator