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LI Yongguang
- Associate Chief Physician, Graduate Supervisor
- Department: Cardiology
- Research Area: Internal medicine
- Research Interests: Pathogenesis of panvascular disease, especially coronary heart disease/glycolipid metabolism
- Contact: yongguangli@shsmu.edu.cn
- MD from Shanghai Jiao Tong University School of Medicine, 2014
- PhD from Shanghai Jiao Tong University, 2014
- Rapid weather changes are associated with daily hospital visitors for atrial fibrillation accompanied by abnormal ECG repolarization: a case-crossover study Shanmei Wu # , Jingyi Guo # , Xin Chen , Jie Wang, Gang Zhao, Shixin Ma, Tianzheng Hao, Jianguo Tan, Yongguang Li Eur J Med Res. 2024 Jan 20;29(1):62.doi:10.1186/s40001-023-01632-3.
- The degree of anxiety and depression in patients with cardiovascular diseases by using mobile APP—a cross-sectional study. Yongguang Li#; Jue Cen#; Junxia Wu#; Min Tang; Jingyi Guo; Jingyu Hang; Qing Zhao; Gang Zhao; Xiaoli Huang; Beibei Han* J Med Internet Res. 2023 Oct 4;25:e48750. doi: 10.2196/48750.
- Metformin suppresses cardiac fibroblast proliferation under high-glucose conditions via regulating mitochondrial complex I protein GRIM-19 involved in the SIRT1/STAT3 signaling pathway. Yongguang Li#; Xiangdong Liu#; Lili Wan; Beibei Han; Shixin Ma; Hongyuan Pan; Junbo Wei*; Xiaofang Cui* Free Radical Biology and Medicine, 2023 Jun 22;206:1-12. DOI: 10.1016/j.freeradbiomed.2023.06.013
- The association between air pollution and the daily hospital visits for atrial fibrillation recorded by ECG: a case-crossover study Jiming Han#; Rui Zhang#; Jingyi Guo; Qingfeng Zheng; Xin Chen; Shanmei Wu; Jianguo Tan*; Yongguang Li* Eur J Med Res. 2023 Aug 12;28(1):282. doi: 10.1186/s40001-023-01266-5.
- Metformin protects high glucose cultured cardiomyocytes from oxidative stress by promoting NDUFA13 expression and mitochondrial biogenesis via the AMPK signaling pathway. Xiangdong Liu#; Yongguang Li#; Guangyu Wang; Yaguang Bi; Yu Zhao; Meiling Yan; Xuebo Liu; Meng Wei; Lili Wan*; Qingyong Zhang* Molecular Medicine Reports, 2020, 22(6): 5262-5270. DOI: 10.3892/mmr.2020.11599
- Diastolic dysfunction predicts the risk of contrast-induced nephropathy and outcome post-emergency percutaneous coronary intervention in AMI patients with preserved ejection fraction. Beibei Han#; Yongguang Li#; Zhifeng Dong; Qing Wan; Hong Shen; Jingbo Li; Meng Wei*; Chengxing Shen* Heart and Vessels, 2018, 33(10): 1149-1158. DOI: 10.1007/s00380-018-1165-x
- Insulin upregulates GRIM-19 and protects cardiac mitochondrial morphology in type 1 diabetic rats partly through PI3K/AKT signaling pathway. Yongguang Li#; Zhifeng Dong#; Kankai Chen#; Yaping He; Xiaoyan Dai; Shuai Li; Jingbo Li; Wei Zhu; Meng Wei* Biochemical and Biophysical Research Communications, 2017, 493(1): 611-617. DOI: 10.1016/j.bbrc.2017.08.144
- High Glucose Induces Down-Regulated GRIM-19 Expression to Activate STAT3 Signaling and Promote Cell Proliferation in Cell Culture. Yongguang Li#; Beibei Han#; Feng Li#; Jianwu Yu; Zhifeng Dong; Gengming Niu; Yanwei Qing; Jingbo Li; Meng Wei*; Wei Zhu* PLos One, 2016, 11(4): e0153659. DOI: 10.1371/journal.pone.0153659
- GRIM-19-mediated Stat3 activation is a determinant for resveratrol induced proliferation and cytotoxicity in cervical tumorderived cell lines. Yongguang Li#; Hongjuan Xia#; Jianping Tao; Ping Xin; Mingya Liu; Jingbo Li; Wei Zhu; Meng Wei* Molecular Medicine Reports, 2015, 11(2): 1272-1277. DOI: 10.3892/mmr.2014.2797
- Myocardial infarction worsens glomerular injury and microalbuminuria in rats with pre-existing renal impairment accompanied by the activation of ER stress and inflammation. Zhifeng Dong#; Penglong Wu#; Yongguang Li#; Yuan Shen; Ping Xin; Shuai Li; Zhihua Wang; Xiaoyan Dai; Wei Zhu; Meng Wei* Molecular Biology Reports, 2014, 41(12): 7911-7921. DOI: 10.1007/s11033-014-3685-5
- 01/01/2018-12/31/2020
Shanghai Jiao Tong University Medical Engineering Interdisciplinary Project, ¥120,000, YG2017QN23
Role: Principal Investigator - 01/01/2019-12/31/2021
National Natural Science Foundation of China, ¥210,000, 81800331
Role: Principal Investigator - 01/01/2020-12/31/2022
Shanghai Municipal Health Commission project, ¥100,000, 201940079
Role: Principal Investigator - 03/01/2023-12/31/2023
China Hospital Development Research Institute, Shanghai Jiao Tong University, Hospital Management Construction Project, ¥20,000,CHDI-2023-B-13
Role: Principal Investigator - 01/01/2025-12/31/2028
National Natural Science Foundation of China, ¥480,000, 82470357
Role: Principal Investigator
