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ZHANG Kaile
- Associate Chief Physician, Graduate Supervisor
- Department: Urology
- Research Area: Repair and Reconstruction of Urethra and Ureter
- Research Interests: Tissue Engineering, Regenerative Medicine, Scar and Fibrosis
- Contact: great_z0313@sjtu.edu.cn
- Fellowship, Wake Forest University, 2014
- PhD from Shanghai Jiao Tong University School of Medicine, 2013
- Master's Degree from Shanghai Jiao Tong University School of Medicine, 2010
- MD from Wuhan University or Science and Technology, 2005
- League Branch Secretary, Department of Urology, Shanghai Sixth People's Hospital
- Hua Y#, Wang K#, Huo Y#, Zhuang Y, Wang Y, Fang W, Sun Y, Zhou G, Fu Q*, Cui W*, Zhang K*. Four-dimensional hydrogel dressing adaptable to the urethral microenvironment for scarless urethral reconstruction. Nat Commun. 2023 Nov 22;14(1):7632.
- Wang L#, Wang K#, Yang M#, Yang X, Li D, Liu M, Niu C, Zhao W, Li W*, Fu Q*, Zhang K*. Urethral Microenvironment Adapted Sodium Alginate/Gelatin/Reduced Graphene Oxide Biomimetic Patch Improves Scarless Urethral Regeneration. Adv Sci (Weinh). 2023 Nov 16:e2302574
- Zhang K#, Muhammad Aqeel Bhutto#, Wang L#, Kai Wang, Jie Liu, Wenyao Li*, Wenguo Cui*, Qiang Fu*. Double-layer nanofibrous sponge tube via electrospun fiber and yarn for promoting urethral regeneration, Adv Fiber Mater. 2023 Jan 5:1-19.
- Zhang K#, Fu Q#, James Y, Chen X, Chandra P, Mo X, Song L, Atala A*, Zhao W*. 3D bioprinting of urethra with PCL/PLCL blend and dual autologous Cells in fibrin hydrogel: an in vitro evaluation of biomimetic mechanical Property and cell growth environment. Acta Biomater. 2017 Mar 1 1;50:154-164. C
- Wang L#, Cheng W#, Zhu J, Li W*, Li D, Yang X, Zhao W, Ren M, Ren J, Mo X, Fu Q*, Zhang K*. Electrospun nanoyarn and exosomes of adipose-derived stem cells for urethral regeneration: Evaluations in vitro and in vivo, Colloids Surf B Biointerfaces. 2022 Jan;209(Pt 2):112218.
- Zhang K#, Yang R#, Chen J, Qi E, Zhou S, Wang Y, Fu Q, Chen R*, Fang X*. Let-7i-5p regulation of cell morphology and migration through distinct signaling pathways in normal and pathogenic urethral fibroblasts, Front Bioeng Biotechnol. 2020 May 14;8:428.
- Zhang K#, Fang X#, Zhu J, Yang R, Wang Y, Zhao W, Mo X*, Fu Q*. Effective Reconstruction of Functional Urethra Promoted With ICG-001 Delivery Using Core-Shell Collagen/Poly(Llactide-co-caprolactone) [P(LLA-CL)] Nanoyarn-Based Scaffold: A Study in Dog Model. Front Bioeng Biotechnol. 2020 Jul 10;8:774.
- Li D#, Liu M#, Li W*, Fu Q, Wang L, Lai E, Zhao W, Zhang K*. Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor Applications. Pharmaceuticals (Basel). 2022 Jun 21;15(7):769.
- Zhang K#, Liu J#, Wang L, Li W, Qi E*, Fu Q*. Application of 3D printed pelvic fracture related urethra and surrounding tissue as preoperative planning model. BMC Urol. 2023 Jan 6;23(1):1.
- (Zhang K#, Wang T#, Cao S，Song L, Hu X, Zhang J, Xu Y, Fu Q*. Multi-Factorial Analysis of Recurrence and Complications of Lingual Mucosa Graft Urethroplasty for Anterior Urethral Stricture: Experience from a Chinese Referral Center. Urology. 2021 Jun;152:96-101.
- 01/01/2025-12/31/2028
National Natural Science Foundation of China, ¥500,000, 82470714
Inflammatory microenvironment-responsive graphene down-regulates macrophage activation to inhibit urethral scar proliferation
Role: Principal Investigator
