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XU Huajun
- Graduate Supervisor, Associate Researcher, Associate Chief Physician
- Department: ENT & HN Surgery
- Research Area: Otorhinolaryngology Head and Neck Surgery
- Research Interests: Obstructive sleep apnea
- Contact: sunnydayxu2010@163.com
- MD from Shanghai Jiao Tong University School of Medicine, 2013
- PhD from Shanghai Jiao Tong University School of Medicine, 2016
- Xu H#, Liu F#, Li Z#, Li X, Liu Y, Li N, Zhang X, Gao Z, Zhang X, Liu Y, Zou J, Meng L, Liu S, Zhu H, Tang X, Wu H, Su K, Chen B, Yu D, Ye H, Chen H, Yi H, Guan J*, Yin S*, Shi Y*. Genome-Wide Association Study of Obstructive Sleep Apnea and Objective Sleep-Related Traits Identifies Novel Risk Loci in Han Chinese Individuals. Am J Respir Crit Care Med. 2022 Jul 12. doi:10.1164/rccm.202109-2044OC.
- Li C#, Peng Y#, Zhu X, Liu Y, Zou J, Zhu H, Li X, Yi H, Guan J*, Zhang X*, Xu H*, Yin S. Independent relationship between sleep apnea-specific hypoxic burden and glucolipid metabolism disorder: a cross-sectional study. Respir Res. 2024;25(1):214. doi: 10.1186/s12931-024-02846-7.
- Li X#, Wang F#, Gao Z, Huang W, Zhang X, Liu F, Yi H, Guan J*, Wu X*, Xu H*, Yin S. Melatonin attenuates chronic intermittent hypoxia-induced intestinal barrier dysfunction in mice. Microbiol Res. 2023 Nov;276:127480. doi:10.1016/j.micres.2023.127480.
- Zhang X#, Wang S#, Xu H*, Yi H, Guan J, Yin S. Metabolomics and microbiome profiling as biomarkers in obstructive sleep apnoea: a comprehensive review.
- Eur Respir Rev. 2021 May 11;30(160):200220. doi: 10.1183/16000617.0220-2020.
- Huajun Xu#, Chen Liang #, Jianyin Zou, Hongliang Yi, Jian Guan *, Meizhen Gu *, Yanhong Feng*, Shankai Yin. Interaction between obstructive sleep apnea and short sleep duration on insulin resistance: a large-scale study. Respir Res. 2020 Jun 16;21(1):151. doi: 10.1186/s12931-020-01416-x.
- 01/01/2018-12/31/2020
National Natural Science Foundation of China, ¥550,000, 82071030
TMAO mediates vascular damage caused by chronic intermittent hypoxia and high cholinergic diet through NLRP3 inflammasome activation
Role: Principal Investigator - 01/01/2021-12/31/2024
National Natural Science Foundation of China , ¥210,000, 81700896
The Role and Mechanism of Intestinal Microflora Bile Acid Metabolic Axis in Atherosclerosis Induced by Chronic Intermittent Hypoxia
Role: Principal Investigator
