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XU Jun
- Associate Chief Physician, Graduate Supervisor
- Department: Traditional Chinese Medicine
- Research Area: Chinese Internal Medicine
- Research Interests: Pathogenesis of metabolic related cognition impairment
- Contact: junjun_030284822@163.com
- PhD from Endocrinology and Metabolic Diseases, Suzhou University, 2022
- MD from Ruijin Hospital/Affiliated Endocrinology Research Institute, Shanghai Jiao Tong University School of Medicine, 2011
- Bachelor from Shandong University of Traditional Chinese Medicine, 2008
- Associate Chief Physician, Department of Traditional Chinese Medicine, Shanghai Sixth People's Hospital
- Xu J, Deng Y, Wang Y, Sun X, Chen S, Fu G. SPAG5-AS1 inhibited autophagy and aggravated apoptosis of podocytes via SPAG5/AKT/mTOR pathway. Cell Prolif. 2020;53(2):e12738. doi:10.1111/cpr.12738
- Xu J, Deng Y, Ke Y, et al. Mutation of Beclin1 acetylation site at K414 alleviates high glucose-induced podocyte impairment in the early stage of diabetic nephropathy by inhibiting hyperactivated autophagy. Mol Biol Rep. 2022;49(5):3919-3926. doi:10.1007/s11033-022-07242-2
- Deng Y; Xu J; Zhang X; Yang J; Zhang D; Huang J; Lv P; Shen W; Yang Y ; Berberine attenuates autophagy in adipocytes by targeting BECN1, Autophagy, 2014, 10(10): 1776- 1786
- Li, Chengqian; Xu, Jun; Yu, Qing; Wang, Ping; Dong, Bingzi; Shen, Liyan; Wang, Qing; Li,Shufa; Yang, Ying; Deng, Yujie ; Mutation of the novel acetylation site at K414R of BECN1 is involved in adipocyte differentiation and lipolysis, JOURNAL OF CELLULAR AND MOLECULAR MEDICINE,2021, 25(14): 6855-6863
- Shanghai Municipal Health Commission, Shanghai Administration of Traditional Chinese Medicine, 2024BJ003, Mechanism Study of Chaihu Ginseng Medicine in Preventing and Treating Cognitive Impairment by Improving Fat Aging Associated Secretory Phenotype (SASP), July 2024 to July 2026, 80000 yuan, presided over
- National Natural Science Foundation of China, Youth Project, 81603476, Research on the autophagy pathway of combination of Astragalus and Coptis chinensis to prevent and treat diabetes nephropathy, January, 2017 to December, 2019, 170000 yuan, presided over
- National Natural Science Foundation of China, general project, 82470853, Research on β - hyodeoxycholic acid produced by Parabacteroides diricholi in intestinal tract improves cognitive impairment related to diabetes by antagonizing farnesol receptor, January, 2025 to December, 2028, 500000 yuan, in research, participating
- National Natural Science Foundation of China, Youth Project, 81600684, Study on Acetylation Regulation of Beclin1 and Its Effect on Adipose Cell Differentiation and Metabolism, from January, 2017 to December, 2019, 200000, participated
- National Natural Science Foundation of China, General Project, 81871092, The role and mechanism of mTORC1/OPN signaling pathway in cathepsin L deficiency induced vascular aging, from January, 2019 to December, 2022, 560000 yuan, participated
- The Three Year Action Plan for the Development of Traditional Chinese Medicine in Shanghai, ZT(2018-2020)-FWTX-2003,Prevention and treatment of diabetes nephropathy with integrated traditional Chinese and western medicine, 2018 to 2020, participated
