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ZHU Jinshui
- Doctoral Supervisor, Professor, Director
- Department: Gastroenterology
- Research Area: Internal Medicine (Digestive Diseases)
- Research Interests: Diagosis and treatment of early gastric cancer and small intestinal diseases
- Contact: zhujs1803@163.com
- Fellowship, Department of Gastroenterology, Shanghai Sixth People's Hospital, 1995
- MD from Shanghai Jiao Tong University School of Medicine, 1992
- PhD from Shanghai Jiao Tong University, 1995
- MPH from Wannan Medical Colleage, 1995
- Director, Department of Gastroenterology, Shanghai Sixth People's Hospital
- Chairman, Enteropathy and Capsule endoscopy Society of Chinese Integrated Association;
- Chairman, Digestion Society, Shanghai Association of Chinese Integrative Medicine;
- Committee, Digestion Society of Shanghai Medical Association,etc.
- Fan HN*, Chen ZY*, Chen XY, Chen M, Yi YC, Zhu JS#, Zhang J#. METTL14-mediated m6A modification of circORC5 suppresses gastric cancer progression by regulating miR-30c-2-3p/AKT1S1 axis. Mol Cancer, 2022, doi: 10.1186/s12943-022-01521-z.
- Yi YC, Chen XY, Zhang J#, Zhu JS#. Novel insights into the interplay between m6A modification and noncoding RNAs in cancer. Mol. Cancer, 2020, doi: 10.1186/s12943-020-01233-2.
- Zhang J*, Hou L*, Liang R*, Chen X, Zhang R, Chen W, Zhu J#. CircDLST promotes the tumorigenesis and metastasis of gastric cancer by sponging miR-502-5p and activating the NRAS/MEK1/ERK1/2 signaling. Mol. Cancer, 2019, doi: 10.1186/s12943-019-1015-1.
- Chen XY, Zhang J#, Zhu JS#. The role of mA RNA methylation in human cancer. Mol. Cancer, 2019, doi: 10.1186/s12943-019-1033-z.
- Wang H*, Chen W*, Jin M, Hou L, Chen X, Zhang R, Zhang J#, Zhu J, CircSLC3A2 functions as an oncogenic factor in hepatocellular carcinoma by sponging miR-490-3p and regulating PPM1F expression. Mol. Cancer, 2018, doi: 10.1186/s12943-018-0909-7.
- Liu H*, Liu Y*, Bian Z*, Zhang J*, Zhang R, Chen X, Huang Y, Wang Y, Zhu J#. Circular RNA YAP1 inhibits the proliferation and invasion of gastric cancer cells by regulating the miR-367-5p/p27 axis. Mol. Cancer, 2018, doi: 10.1186/s12943-018-0902-1.
- Zhang J*, Liu H*, Hou L, Wang G, Zhang R, Huang Y, Chen X, Zhu J#. Circular RNA_LARP4 inhibits cell proliferation and invasion of gastric cancer by sponging miR-424-5p and regulating LATS1 expression. Mol. Cancer, 2017, doi: 10.1186/s12943-017-0719-3.
- Chen XY*, Liang R*, Yi YC, Fan HN, Chen M, Zhang J#, Zhu JS#. The m6A Reader YTHDF1 Facilitates the Tumorigenesis and Metastasis of Gastric Cancer via USP14 Translation in an m6A-Dependent Manner. Front Cell Dev Biol. 2021, doi: 10.3389/fcell.2021.647702.
- Yi YC, Liang R, Chen XY, Fan HN, Chen M, Zhang J#, Zhu JS#. Dihydroartemisinin Suppresses the Tumorigenesis and Cycle Progression of Colorectal Cancer by Targeting CDK1/CCNB1/PLK1 Signaling. Front Oncol. 2021, doi: 10.3389/fonc.2021.768879.
- Huang Y*, Zhang J*#, Hou L, Wang G, Liu H, Zhang R, Chen X, Zhu J#. LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway. J Exp Clin Cancer Res. 2017, doi: 10.1186/s13046-017-0666-2.
- Zhang J*, Jin M*, Chen X*, Zhang R, Huang Y, Liu H, Zhu J#. Loss of PPM1F expression predicts tumour recurrence and is negatively regulated by miR-590-3p in gastric cancer. Cell Prolif. 2018, doi: 10.1111/cpr.12444.
- 01/2021-12/2024
National Natural Science Foundation of China, ¥550,000, 82074161
Sanguinarine regulates the effect of m6A methyltransferase METTL14/hsa_circ_0007612 axis on gastric cancer metastasis
Role: Project leader - 06/2020-12/2022
Shanghai Health Commission, ¥100,000, ZHYY-ZHXY-JHZX-202-013
Clinical Study on Ulcerative Colitis Treated with Combination of Traditional Chinese and Western Medicine
Role: Project leader - 10/2018-10/2021,
Shanghai Science and Technology Commission-Medical, Industrial and Enterprise Key Cooperation Project,¥250000,18DZ1930309,
Research on the application of capsule endoscopic system in the follow-up of patients with esophageal diseases
Role: Project leader - 08/2017-08/2020
Shanghai Science and Technology Commission-Innovative Technology Project, ¥200000,17411966500
Digital endoscopic imaging diagnosis of intractable diseases of the small intestine
Role: Project leader - 01/2016-12/2019
National Natural Science Foundation of China, ¥570000,81573747
Long non-coding RNA AK023391 mediate the molecular mechanism of matrine in gastric cancer
Role: Project leader - 01/2014-01/2017
National Natural Science Foundation of China, ¥230000,81302093
Molecular effects of HGMB signaling against human gastric cancer
Role: Project leader - 01/2013-12/2016
National Natural Science Foundation of China, ¥600000,80172772
Molecular regulation mechanism of LATS1 transduction on Hippo-YAP signaling pathway in gastric cancer cells
Role: Project leader - 05/2010-12/2012
Shanghai Science and Technology Commission-Key Project of Animal Experimental Model, ¥200000,10140902500
Establishment and application of a transplantation model for liver metastasis of orthotopic gastric cancer in nude mice with severe combined immunodeficiency
Role: Project leader
- [Zhu Jin Shui (1/5)] (2019), “A magnetically controlled capsule endoscopic device for gastroenterology”, ZL 201821322570.2
- [Zhu Jin Shui (1/8)] (2021), “A grading crushing device for the preparation of traditional Chinese medicine”, ZL 202122086376.7
