• Associate Chief Physician, Department of Orthopedics, Shanghai Sixth People's Hospital, 2012-present

PhD from Suzhou University, 2013-2016

1. Zhang W, Lin Y, Zong Y, Ma X, Jiang C, Shan H, Xia W, Yin L, Wang N, Zhou L, Zhou Z#, Yu X#. Staphylococcus aureus Infection Initiates Hypoxia-Mediated Transforming Growth Factor-β1 Upregulation to Trigger Osteomyelitis. mSystems. 2022 Aug 30;7(4):e0038022.
2. Xia W, Li N, Shan H, Lin Y, Yin F, Yu X#, Zhou Z#. Gallium Porphyrin and Gallium Nitrate Reduce the High Vancomycin Tolerance of MRSA Biofilms by Promoting Extracellular DNA-Dependent Biofilm Dispersion. ACS Infect Dis. 2021 Aug 13;7(8):2565-2582.
3. Zhou Z, Lin Y, Pan C, Wang N, Zhou L, Shan H, Gao Y, Yu X. IL-15 deficiency alleviates steroid-induced osteonecrosis of the femoral head by impact osteoclasts via RANKL-RANK-OPG system. Immun Ageing. 2020 Jun 12;17:19.
4. Jiang F, Zong Y, Ma X, Jiang C,Shan H, Lin Y, Xia W, Yin F, Wang N, Zhou L, Zhou Z#, Yu X#. MiR-26a attenuated bone-specific insulin resistance and bone quality in diabetic mice. Mol Ther Nucleic Acids. 2020 Mar 29;20:459-467.
5. Jiang C, Xia W, Wu T, Pan C, Shan H, Wang F, Zhou Z#, Yu X#. Inhibition of microRNA-222 up-regulates TIMP3 to promotes osteogenic differentiation of MSCs from fracture rats with type 2 diabetes mellitus. J Cell Mol Med. 2020 Jan;24(1):686-694.
6. Jiang F, Yin F, Lin Y, Xia W, Zhou L, Pan C, Wang N, Shan H, Zhou Z#, Yu X#. The promotion of bone regeneration through CS/GP-CTH/antagomir-133a/b sustained release system. Nanomedicine. 2020 Feb;24:102116.
7. Pan C, Shan H, Wu T, Liu W, Lin Y, Xia W, Wang F, Zhou Z#, Yu X#. 20(S)-Protopanaxadiol Inhibits Titanium Particle-Induced Inflammatory Osteolysis and RANKL-Mediated Osteoclastogenesis via MAPK and NF-κB Signaling Pathways. Front Pharmacol. 2019 Jan 18;9:1538.
8. Zhou Z, Pan C, Wang N, Zhou L, Shan H, Gao Y, Yu X. A high-fat diet aggravates osteonecrosis through a macrophage-derived IL-6 pathway. Int Immunol.  2019 Mar 28;31(4):263-273. 
9. Zhou Z, Seta J, Markel DC, Song W, Yurgelevic SM, Yu XW, Ren W. Release of vancomycin and tobramycin from polymethylmethacrylate cements impregnated with calcium polyphosphate hydrogel.  J Biomed Mater Res B Appl Biomater.2018 Nov;106(8):2827-2840. 
10. Zhou Z, Pan C, Lu Y, Gao Y, Liu W, Yin P, Yu X. Combination of Erythromycin and Curcumin Alleviates Staphylococcus aureus Induced Osteomyelitis in Rats. Front Cell Infect Microbiol. 2017 Aug 24;7:379. 
     

• 01/01/2015-12/31/2018
  National Natural Science Foundation of China, ¥720,000, 81472110
  A new reinforced calcium phosphate cement with EM-PCLCol/EM-PVA-nanofibers for the treatment of osteomyelitis
  Role: Project leader

1. [Wenyang Xia, Xiaowei Yu, Zubin Zhou, Haojie Shan, Yiwei Lin, Fuli Yin] (2022), “A limb fixing device for orthopedic clinical surgery”, CN2022/01/04; ZL 202120877962.0
2. [Wenyang Xia, Xiaowei Yu, Zubin Zhou, Haojie Shan, Yiwei Lin, Fuli Yin] (2021), “An incision tractor for orthopedic surgery”, CN2021/05/04; ZL 202120982150.2
3. [Wenyang Xia, Xiaowei Yu, Zubin Zhou] (2021), “A ligament spine rehabilitation therapeutic instrument for sports medicine”, CN2021/11/23; ZL 202021261888.1
4. [Xiaowei Yu, Changqing Zhang, Zubin Zhou, Chenhao Pan, Haojie Shan] (2020), “An injection device for bone cavity filling”, CN2020/04/07; ZL 201920288484.2
5. [Yuqiang Sun, Xiaowei Yu, Zubin Zhou, Mingjie Tang, Xiaochun Peng] (2013), “An internal fixator for acetabular posterior wall fracture”, CN2013/12/11; ZL 201320018250.9

• Third Prize of Science and Technology Progress Award in Pudong New Area in 2018