ZHOU Jian  

  • Chief Physician, Doctoral Supervisor, Professor
  • Department: Endocrinology and Metabolism
  • Research Area: Internal Medicine (Endocrinology and Metabolism)
  • Research Interests: Pathogenesis of diabetes and obesity, Diabetes advanced technologies and diabetes interventions, especially clinical research on continuous glucose monitoring (CGM)
  • Contact: zhoujian@sjtu.edu.cn
  • Visiting Scholar, Pennington Biomedical Research Center, Chronic Disease Epidemiology Laboratory,  2019
  • MD&PhD from Shanghai Jiao Tong University School of Medicine, 2010
  • MB from Shanghai Second Medical University, 2000
  • Deputy Director, Department of  Endocrinology & Metabolism, Shanghai Sixth People's Hospital
  • Vice Chairman,  Shanghai Medical Association Diabetes Branch
  • Vice Chairman,  Metabolic Medical Engineering Committee, Shanghai Biomedical Engineering Society
  • Leader, Advanced Technology for the Monitoring and Treatment of Diabetes Group, Shanghai Medical Association Diabetes Branch
  • Associate Editor, Endocrine
  • Editorial Board Member, Cardiovascular Diabetology
  • Editorial Board Member, Chinese Journal of Internal Medicine
  1. Chen S, Lu J, Peng D, Liu F, Lu W, Zhu W, Zhou J#, Jia W. Effect of a Mobile Health Technology-Based Diabetes Education Program on Glucose Control in Patients With Type 2 Diabetes Initiating Premixed Insulin: A Prospective, Multicenter, Observational Study. Diabetes Care, 2023, doi:10.2337/dc22-0510.
  2. Cai J, Yang Q, Lu J, Shen Y, Wang C, Chen L, Zhang L, Lu W, Zhu W, Xia T, Zhou J#. Impact of the Complexity of Glucose Time Series on All-Cause Mortality in Patients With Type 2 Diabetes. J Clin Endocrinol Metab, 2023, doi:10.1210/clinem/dgac692.
  3. Wang Y, Lu J, Ni J, Wang M, Shen Y, Lu W, Zhu W, Bao Y, Rodbard D, Vigersky RA, Jia W, Zhou J#. Association between glycaemia risk index (GRI) and diabetic retinopathy in type 2 diabetes: A cohort study. Diabetes Obes Metab, 2023, doi:10.1111/dom.15068.
  4. Zhou J*, Chen S, Cheng J, Zhu J, Lou Y, Bao Y, Jia W. Ultra rapid lispro improves postprandial glucose control versus lispro in combination with insulin glargine/degludec in adults with type 2 diabetes: a prospective, randomized, double-blind, phase 3 trial. Sci Bull (Beijing) , 2022, doi:10.1016/j.scib.2022.08.002.
  5. Lu J, Wang C, Shen Y, Chen L, Zhang L, Cai J, Lu W, Zhu W, Hu G, Xia T, Zhou J#. Time in Range in Relation to All-Cause and Cardiovascular Mortality in Patients With Type 2 Diabetes: A Prospective Cohort Study. Diabetes Care, 2021, doi:10.2337/dc20-1862.
  6. Shen Y, Fan X, Zhang L, Wang Y, Li C, Lu J, Zha B, Wu Y, Chen X, Zhou J#, Jia W. Thresholds of Glycemia and the Outcomes of COVID-19 Complicated With Diabetes: A Retrospective Exploratory Study Using Continuous Glucose Monitoring. Diabetes Care, 2021, doi:10.2337/dc20-1448.
  7. Yu G, Zhang M, Gao L, Zhou Y, Qiao L, Yin J, Wang Y, Zhou J#, Ye H. Far-red light-activated human islet-like designer cells enable sustained fine-tuned secretion of insulin for glucose control in T1D mice. Mol Ther, 2022, doi:10.1016/j.ymthe.2021.09.004.
  8. Lu J, Wang C, Cai J, Shen Y, Chen L, Zhang L, Lu W, Zhu W, Hu G, Xia T, Zhou J#. Association of HbA1c With All-cause Mortality Across Varying Degrees of Glycemic Variability in Type 2 Diabetes.  J Clin Endocrinol Metab, 2021, doi:10.1210/clinem/dgab532.
  9. Lu J, Home PD, Zhou J#. Comparison of Multiple Cut Points for Time in Range in Relation to Risk of Abnormal Carotid Intima-Media Thickness and Diabetic Retinopathy. Diabetes Care, 2020, doi:10.2337/dc20-0561.
  10. Lu J, Ma X, Zhou J#, Zhang L, Mo Y, Ying L, Lu W, Zhu W, Bao Y, Vigersky RA, Jia W. Association of Time in Range, as Assessed by Continuous Glucose Monitoring, With Diabetic Retinopathy in Type 2 Diabetes. Diabetes Care, 2018, doi:10.2337/dc18-1131. 
  • 09/01/2022-08/31/2025
    Program of Shanghai Academic Research Leader, ¥400,000, 22XD1402300
    Exploration and clinical application of new core metrics for glucose control in patients with diabetes
    Role: Principal Investigator
  • 01/01/2022-12/31/2025
    National Natural Science Foundation of China (General Program), ¥550,000, 82170889
    Mechanism of ANKRD53 in promoting lipid mobilization and alleviating the occurrence and development of obesity
    Role: Principal Investigator
  • 07/01/2019-06/30/2022
    Shanghai Municipal Education Commission Gaofeng Clinical Medicine Grant Support (Second Round),  ¥1,000,000, 20161430
    Application of continuous glucose monitoring and 1,5-anhydroglucitol to evaluate the risk of macrovascular complications in type 2 diabetes and adverse pregnancy outcomes in gestational diabetes
    ​​​​​​​Role: Principal Investigator
  • 01/01/2019-12/31/2021
    National Natural Science Foundation of China (General Program), ¥570,000, 81873646
    Mechanism of PDIA5 in regulating gluconeogenesis through alleviating endoplasmic reticulum stress
    ​​​​​​​Role: Principal Investigator
  • 12/31/2018-12/31/2022
    National Key Research and Development Program of China,  ¥3,480,000, 2018YFC2001004
    CGM-based health assessment of glucose metabolism and individualized diabetes management
    ​​​​​​​Role: Project leader
  • 01/01/2017-12/31/2019
    Natural Science Foundation of Xinjiang Uygur Autonomous Region of China,  ¥70,000, 2016D01C084
    Study on the relationship and mechanism between 1,5-anhydroglucitol and atherosclerosis in patients with type 2 diabetes 
    ​​​​​​​Role: Principal Investigator
  • 07/01/2015-09/30/2018    
    Shanghai Municipal Science and Technology Commission Medical Guidance Projects, ¥200,000, 15411963500
    A new indicator for postprandial blood glucose fluctuation-Establishment and clinical application of normal value of 1,5-anhydroglucitol
    ​​​​​​​Role: Principal Investigator
  • 09/30/2012-08/31/2014
    Shanghai Rising-Star Program,  ¥200,000, 12QA1402500
    Regulatory mechanism and intervention research of glycemic variability in type 2 diabetes
    ​​​​​​​Role: Principal Investigator
  • 01/01/2012-12/31/2014
    National Natural Science Foundation of China (Young Scientist Fund), ¥220,000, 81100590
    Circadian rhythm free fatty acid-mediated fibroblast growth factor 21 on the regulation of glucose and lipid homeostasis
    ​​​​​​​Role: Principal Investigator
  • 11/01/2011-10/31/2014
    Shanghai Medical Program for Outstanding Young Talent, ¥600,000,XYQ2011013
    Establishment of new technology of real-time continuous glucose monitoring and mechanism of glycemic fluctuation
    Role: Principal Investigator