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ZHANG Zhichang
- Graduate Supervisor, Researcher, Associate Chief Physician
- Department: Orthopedics
- Research Area: Surgery (Orthopedics)
- Research Interests: Clinical research of bone and soft tissue tumors
- Contact: zzc163mail@163.com
- MD from Shanghai Jiao Tong University School of Medicine, 2007
- PhD from Shanghai Jiao Tong University School of Medicine, 2019
- Bachelor's degree from Fudan University, 2001
- Associate Chief Physician, Department of Orthopedics, Shanghai Sixth People's Hospital
- Executive Committee Member of the Bone Tumor Special Committee of the Orthopedics and Traumatology Branch of the China Association for the Promotion of Traditional Chinese Medicine Research
- Chao Liang#, Naping Xiong#, Mengfan Liu#, Yue Chen, Wenxin Li, Jiankun Xu, Yin Sun, Yongjie Wang, Yang Dong, Wenpei Fan*, Yifeng Zhang*, Zhichang Zhang*. Manganese immunotherapy for treating osteosarcoma: Glycosylating 1V209 anchored MnO2 nanosheets prompt pro-inflammatory macrophage polarization. Nano Today, 2023, 48: 101670.
- Zhengzhe Han#, Lanlan Dong#, Ang Li#, Zongyue Li, Landie Fu, Zhichang Zhang**, Xiang Li*, Xiaolin Li ***. Efficient angiogenesis-based wound healing through hydrogel dressing with extracellular vesicles release. Materials Today Bio, 2022,16: 100427.
- Zhichang Zhang*, Weiping Ji*, Jin Huang*, Yawen Zhang, Yan Zhou, Jianjun Zhang, Yang Dong, Ting Yuan, Qingcheng Yang, Xiaomin Ding, Lina Tang, Hongtao Li, Junyi Yin, Yonggang Wang, Jia Fei, TongJi, Bin Zhang#, Peizhan Chen#, and Haiyan Hu. Characterization of the tumor microenvironment phenotypes in malignant tissues and pleural effusion from advanced osteoblastic osteosarcoma patients. Clinical and Translational Medicine,2022; 2;12:e1072.
- Ang Li, Zhengzhe Han, Zongyue Li, Jingfeng Li, Xiaolin Li, Zhichang Zhang. A PTHrP-2 loaded adhesive cellulose acetate nanofiber mat as wound dressing accelerates wound healing.Materials & Design, 2021, 212:110241-.
- Chenliang Zhou, Zhichang Zhang, Xiaoshi Zhu, Guowei Qian, Yan Zhou, Yong Sun, Wenxi Yu, Jiahui Wang, Haiyang Lu, Feng Lin, Zan Shen, Shuier Zheng. N6-Methyladenosine modifification of the TRIM7 positively regulates tumorigenesis and chemoresistance in osteosarcoma through ubiquitination of BRMS1. EBioMedicine.2020,59:102955.
- Chao Liang, Yongjie Wang, MM, Yuxuan Wei, MM, Yang Dong, MD, Zhichang Zhang. Identifification of Novel EXT Mutations in Patients with Hereditary Multiple Exostoses Using Whole-Exome Sequencing.Orthopaedic Surgery 2020;12:990–996. DOI: 10.1111/os.12660.
- Zhi-Chang Zhang, Chun Tang, Yang Dong, Jing Zhang, Ting Yuan*, Xiao-Lin* Li.Targeting LncRNA-MALAT1 suppresses the progression of osteosarcoma by altering the expression and localization of β-catenin. J Cancer.2018;9(1):71-80.
- Jing Zhang, Yuxuan Wei, Yue Gong, Yang Dong*, Zhichang Zhang*.Reconstruction of iliac crest defect after autogenous harvest with bone cement and screws reduces donor site pain. BMC Musculoskeletal Disorders.2018;19:237.
- Zhi-Chang Zhang, Chun Tang, Yang Dong, Jing Zhang, Ting Yuan, Shi-Cong Tao*, Xiao-Lin* Li.Targeting the long noncoding RNA MALAT1 blocks the pro-angiogenic effects of osteosarcoma and suppresses tumour growth.Int J Bio Sci.2017;13(11):1398-1408.
- 01/01/2023-12/31/2025
Clinical Project of Shanghai Municipal Health Commission, ¥100,000, 202240141
A comparative study of the therapeutic effects of biological stems and cement stems in the revision surgery of distal femoral tumor type prostheses
Role: Project leader - 11/01/2020-10/31/2022
Shanghai Pujiang Talent Plan Project(class D), ¥300,000, 2020PJD042
Study on the Mechanism and Effect of Functionalized Injectable Short Fiber Composite Hydrogel in Inhibiting Osteosarcoma and Promoting Bone Formation
Role: Project leader
- [Zhang Zhichang] (2020), “A new type of glenoid humeral joint prosthesis after scapuloplasty”, CN 212415999 U; ZL 2020 2 0397344.1
