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ZHANG Changqing  

  • Doctoral Supervisor, Professor
  • Department: Orthopedics
  • Research Area: Surgery (Orthopedics)
  • Research Interests: Clinical and basic study of femoral head necrosis
  • Contact: zhangcq@sjtu.edu.cn
Biography Positions Publications Patents Other
  • PhD from Shanghai Medical University, 1996
  • Director, National Center for Orthopedics, Shanghai Sixth People's Hospital 
  • Director, Shanghai Jiao Tong University School of Orthopaedics, School of Medicine
  • Former Chairman, Microsurgery Society of Chinese Medical Association
  • Chairman, Orthopaedic Society of Shanghai Medical Association
  1. Miao Y, Chen Y, Xue F, Liu K, Zhu B, Gao J, Yin J, Zhang C, Li G. Contribution of ferroptosis and GPX4's dual functions to osteoarthritis progression. EBioMedicine. 2022 Feb;76:103847. doi: 10.1016/j.ebiom.2022.103847
  2. Shao R, Suo J, Zhang Z, Kong M, Ma Y, Wen Y, Liu M, Zhuang L, Ge K, Bi Q, Zhang C, Zou W. H3K36 methyltransferase NSD1 protects against osteoarthritis through regulating chondrocyte differentiation and cartilage homeostasis. Cell Death Differ. 2024 Jan;31(1):106-118. doi: 10.1038/s41418-023-01244-8
  3. Tang Q, Hu Z, Jin H, Zheng G, Yu X, Wu G, Liu H, Zhu Z, Xu H, Zhang C, Shen L. Microporous polysaccharide multilayer coated BCP composite scaffolds with immobilised calcitriol promote osteoporotic bone regeneration both in vitro and in vivo. Theranostics. 2019 Jan 30;9(4):1125-1143. doi: 10.7150/thno.29566
  4. Ding P, Tan Q, Wei Z, Chen Q, Wang C, Qi L, Wen L, Zhang C, Yao C. Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation. Bone Res. 2022 May 27;10(1):42. doi: 10.1038/s41413-022-00210-3
  5. Liu P, Gao Y, Luo P, Yu H, Guo S, Liu F, Gao J, Xu J, Wang S, Zhang C. Glucocorticoid-induced expansion of classical monocytes contributes to bone loss. Exp Mol Med. 2022 Jun;54(6):765-776. doi: 10.1038/s12276-022-00764-6
  6. Gao J, Qin A, Liu D, Ruan R, Wang Q, Yuan J, Cheng TS, Filipovska A, Papadimitriou JM, Dai K, Jiang Q, Gao X, Feng JQ, Takayanagi H, Zhang C, Zheng MH. Endoplasmic reticulum mediates mitochondrial transfer within the osteocyte dendritic network. Sci Adv. 2019 Nov 20;5(11):eaaw7215. doi: 10.1126/sciadv.aaw721
  7. Tang Q, Lim T, Wei XJ, Wang QY, Xu JC, Shen LY, Zhu ZZ, Zhang CQ. A free-standing multilayer film as a novel delivery carrier of platelet lysates for potential wound-dressing applications. Biomaterials. 2020 Oct;255:120138. doi: 10.1016/j.biomaterials.2020.120138
  8. Tang Q, Lim T, Shen LY, Zheng G, Wei XJ, Zhang CQ, Zhu ZZ. Well-dispersed platelet lysate entrapped nanoparticles incorporate with injectable PDLLA-PEG-PDLLA triblock for preferable cartilage engineering application. Biomaterials. 2021 Jan;268:120605. doi: 10.1016/j.biomaterials.2020.120605
  9. Cai Q, Fu K, Jia W, Li X, He H, Yao Z, Chen X, Dong Y, Wang Q, Kang B, Qian B, Chen S, Zhang C. In-hospital waiting time to surgery and functional outcomes in geriatric hip fractures: a directed acyclic graph-based preplanned analysis from a prospective multicenter cohort study. Int J Surg. 2023 Jun 1;109(6):1612-1619. doi: 10.1097/JS9.0000000000000385
  10. Yin J, Pan S, Guo X, Gao Y, Zhu D, Yang Q, Gao J, Zhang C, Chen Y. Nb2C MXene-Functionalized Scaffolds Enables Osteosarcoma Phototherapy and Angiogenesis/Osteogenesis of Bone Defects. Nanomicro Lett. 2021 Jan 4;13(1):30. doi: 10.1007/s40820-020-00547-6
  11. Zhu H, Zhou L, Wang Q, Cai Q, Yang F, Jin H, Chen Y, Song Y, Zhang C. Glucagon-like peptide-1 receptor agonists as a disease-modifying therapy for knee osteoarthritis mediated by weight loss: findings from the Shanghai Osteoarthritis Cohort. Ann Rheum Dis. 2023 Sep;82(9):1218-1226. doi: 10.1136/ard-2023-223845
  1. [Changqing Zhang] (2022), “ DEVICE,KIT FOR REPAIRING AND FIXINGARTICULAR ARTILAGE,AND METHODFOR THE SAME”, US  Patent 20220226128A1
  2. [Changqing Zhang] (2021), “ GREFFON PERMETTANT LA REPARATION DE LESIONS DU CARTILAGE ARTICULAIRE ET SON PROCEDE”, Canadian Patent 3,050,658
  3. [Changqing Zhang] (2022), GERMAN Patent, B32804EP
  4. [Changqing Zhang] (2019), “ CENTRIFUGE APPARATUS FORSEPARATING BLOOD COMPONENTS”, US  Patent  10286140B2
  • PRP transformation ¥2,000,000；
  • Hard tissue microtome transformation ¥5,000,000

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