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ZHANG Wei  

  • Doctoral Supervisor, Professor, Associate Professor
  • Department: Orthopedics
  • Research Area: Surgery (Orthopedics)
  • Research Interests: New technologies, materials, and products for trauma orthopedics
  • Contact: orthozhang@163.com
Biography Positions Publications Research Projects Patents Other
  • Fellowship, Humboldt University School of Medicine, 2006
  • Fellowship, Regensburg University School of Medicine, 2003
  • PhD from Second Military Medical University, 2001
  • MD from Second Military Medical University, 1993
  • Deputy Director, Department of Orthopedics, Shanghai Sixth People's Hospital
  1. Qi X, Liu C, Si J, Yin B, Huang J, Wang X, Huang J, Sun H, Zhu C, Zhang W(*). A bioenergetically-active ploy (glycerol sebacate)-based multiblock hydrogel improved diabetic wound healing through revitalizing mitochondrial metabolism. Cell Prolif. 2024 Feb 13:e13613. doi: 10.1111/cpr.13613. Epub ahead of print. PMID: 38351579.
  2. Yin BH, Liu CJ, Sherrier MC, Sun H, Zhang W(*). Compressive buttress compared with off-axial screw fixation for vertical femoral neck fractures in young adults: a prospective, randomized controlled trial. J Orthop Surg Res. 2024 Jan 6;19(1):42. 
  3. Qi, X., Liu, Y., Yin, X., Zhao, R., Zhang, W., Cao, J., Wang, W., & Jia, W. (2023). Surface-based modified 3D-printed BG/GO scaffolds promote bone defect repair through bone immunomodulation. Composites Part B: Engineering.
  4. Fan ZY, Shu LY, Jin YZ, Sherrier MC, Yin BH, Liu CJ, Zhan S, Sun H, Zhang W(*). Biomechanical evaluation of compression buttress screw and medial plate fixation for the treatment of vertical femoral neck fractures. Injury. 2022 Dec;53(12):3887-3893. doi: 10.1016/j.injury.2022.09.056. Epub 2022 Sep 28. PMID: 36195517.
  5. Wei X, Chen S, Xie T, Chen H, Jin X, Yang J, Sahar S, Huang H, Zhu S, Liu N, Yu C, Zhu P, Wang W, Zhang W(*). An MMP-degradable and conductive hydrogel to stabilize HIF-1α for recovering cardiac functions. Theranostics. 2022 Jan 1;12(1):127-142. doi: 10.7150/thno.63481. PMID: 34987638; PMCID: PMC8690911. 
  6. Sun H, Shu LY, Sherrier MC, Zhu Y, Liu JW, Zhang W（*）. Decreased complications but a distinctive fixation loosening mechanism of fully threaded headless cannulated screw fixation for femoral neck fractures in young adults. J Orthop Surg Res. 2021 Mar 30;16(1):234. 
  7. Chen H, Yin B, Hu B, Zhang B, Liu J, Jing Y, Fan Z, Tian Y, Wei X, Zhang W(*). Acellular fish skin enhances wound healing by promoting angiogenesis and collagen deposition. Biomed Mater. 2021 Apr 9;16(4).
  8. Yin B, Fan Z, Jin Y, Chen H, Zhang B, Liu J, Zhang W(*). Epidermal growth factor/epidermal growth factor receptor moves into the osteoblasts' cell nuclei where it is involved to regulate STAT5's signaling. Biofactors. 2021 May;47(3):351-362. 
  9. Yin BH, Chen HC, Zhang W(*), Li TZ, Gao QM, Liu JW. Effects of hypoxia environment on osteonecrosis of the femoral head in Sprague-Dawley rats. J Bone Miner Metab. 2020 Nov;38(6):780-793.
  10. Zhang Y, Yan C, Zhang L, Zhang W, Wang G. Comparison of Ordinary Cannulated Compression Screw and Double-Head Cannulated Compression Screw Fixation in Vertical Femoral Neck Fractures. Biomed Res Int. 2020 Dec 30;2020:2814548. doi: 10.1155/2020/2814548. PMID: 33457404; PMCID: PMC7787733.
  11. Jingwen Liu, Baokun Zhang, Bohao Yin, Hongchi Chen, Hui Sun, Wei Zhang（*） Biomechanical Evaluation of the Modified CannulatedScrews Fixation of Unstable Femoral Neck Fracture with Comminuted Posteromedial Cortex. Biomed Res Int2019：1-8. 
  12. Zhang B, Liu J, Zhang W (*): Ordinary cannulated compression screws or headless cannulated compression screws? A synthetic bone biomechanical study in the fixation of vertical femoral neck fracture. Biomed Res Int 2018.4,489.
  13. Zhang B, Liu J, Zhu Y, Zhang W (*): A new configuration of cannulated screw fixation in the treatment of vertical femoral neck fractures. Int Orthop 2018.11.22. 
  14. Sun H, He QF, Zhang BB, Zhu Y, Zhang W, Chai YM. A biomechanical evaluation of different fixation strategies for posterolateral fragments in tibial plateau fractures and introduction of the 'magic screw'. Knee. 2018 Jun;25(3):417-426. doi: 10.1016/j.knee.2018.03.015. Epub 2018 Apr 18. PMID: 29678367. 
  • 01/01/2024-12/31/2027
    National Natural Science Foundation of China (General Program), ¥490,000.00 No.82372390
    The role and mechanism of the PICHS-iMSC-Exos system in regulating mitochondrial autophagy for bone defect repair.
    Role:  Project leader
  • 08/21/2022-08/20/2024
    Shanghai Health Science Popularization Talent ability Promotion Project, ¥200,000.00 No.JKKPYL-2022-07
    Hip health in china: Popularize science in the countryside
    Role: Project leaderr
  • 10/01/2020-09/30/2023
    Program of Shanghai Subject Chief Scientist , ¥400,000.00 No.20XD1402600
    Study and clinical application of new classification system and internal fixation technique for femoral neck fracture
    Role: Project leader
  • 09/01/2018-06/31/2021
    National Key Research and Development Project, ¥2,870,000.00 No.2018YFC1105604
    Biological evaluation and clinical application research of medical marine functional products.
    Role: Project leader
  1. [Wei Zhang, Hui Sun, Bohao Yin] (2018), “A new type of dynamic feedback hollow pressurized screw fixation system.”CN201820545266.8
  2. [Wei Zhang,  Bohao Yin] (2021), “A compression screw for femoral neck fractures and its application method.”CN202111088183.3
  3. [Wei Zhang, Junjie Guan, Hui Sun, Bohao Yin] (2023), “A double-headed compression power-driven screw.”CN202310271724.9
  4. [Wei Zhang, Junjie Guan, Hui Sun, Bohao Yin] (2023), “A power-driven hollow screw and its matching screwdriver.”CN202023115821.X
  • Achievement transformation: Persistent compression screw; Transformation amount: ¥1,000,000.00
  • National Science and Technology Progress Award; Second Prize
  • Shanghai Municipal Science and Technology Invention Prize; First Prize.
  • Shanghai Medical Science and Technology Award; First Prize.
  • Shanghai Science Popularization Education Innovation Award; Second Prize

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