ZHANG Hao  

  • Chief Physician, Graduate Supervisor
  • Department: Osteoporosis and Bone Diseases
  • Research Area: Internal Medicine (Endocrinology and Metabolism)
  • Research Interests: Pathogenesis of metabolic bone disease and hereditary bone disease
  • Contact: zhanghaozcl@163.com
  • MD from Shanghai Jiao Tong University School of Medicine, 2015
  • Master's Degree from Shanghai Jiao Tong University School of Medicine, 2009
  • Bachelor's Degree from Shanghai Second Medical University, 1998
  • Chief Physician, Department of Osteoporosis and Bone Diseases, Shanghai Sixth People's Hospital
  • Vice Chairman, Youth Committee of the Sixth Committee of Chinese Society of Osteoporosis and bone Mineral Research
  • Member, 8th Committee of Osteoporosis Branch of Shanghai Medical Association
  • Member, second Committee of Osteoporosis Branch of China Geriatric Health Care Medical Research Society
  • Member, first Academic Committee of China Clinical Case Results Database 
  1. Zhang H, Gu JM, Chao AJ, Cheng Q, Teng DH, Yu JM, Wang BW, Huo YN, Mao L, Zhang Q, Yang H, Yan SG, Zhang KQ, Zhao XL, Lin H, Pei Y, Yuan Z, Dai RC, He L, Chen L, Su YF, Deng ZL, You L, Ban B, Zhu M, Cao YL, Zhu YK, Li ZJ, Zhang Z, Yi CQ, Lu YB, Wang G, Han CC, Wang ZJ, Li XX, Zhang ZL. A phase III randomized, double-blind, placebo-controlled trial of the denosumab biosimilar QL1206 in postmenopausal Chinese women with osteoporosis and high fracture risk. Acta Pharmacol Sin, 2023;44(2):446-453.
  2. Mei Y, Jiang Y, Shen L, Meng Z, Zhang Z#, Zhang H#. Echocardiographic abnormalities and joint hypermobility in Chinese patients with Osteogenesis imperfecta, Orphanet Journal of Rare Diseases, 2024; 19(1): 116.
  3. Mei Y, Jiang Y, Zhang Z#, Zhang H#. Muscle and bone characteristics of a Chinese family with spinal muscular atrophy, lower extremity predominant 1 (SMALED1) caused by a novel missense DYNC1H1 mutation. BMC Med Genomics, 2023;16(1): 47.
  4. Mei YZ, Zhang H#, Zhang ZL#. Comparing Clinical and Genetic Characteristics of De Novo and Inherited COL1A1/COL1A2 Variants in a Large Chinese Cohort of Osteogenesis Imperfecta. Front Endocrinol (Lausanne), 2022;13:935905.
  5. Zhang H, He JW, Wang C, Zhang Z, Yue H, Hu WW, Gu JM, Hu YQ, Li M, Fu WZ, Zhang ZL.Associations of polymorphisms in the SOST gene and bone mineral density in postmenopausal Chinese Women.Osteoporos Int, 2014; 25(12):2797-2803.
  6. Zhang H, Hu YQ, Zhang ZL. Age trends for hip geometry in Chinese men and women and the association with femoral neck fracture. Osteoporos Int, 2011;22(9):2513-2522.
  7. Zhang H, Yue H, Wang C, Gu J, He J, Fu W, Hu W, Zhang Z. Novel mutations in the SEC24D gene in Chinese families with autosomal recessive osteogenesis imperfecta. Osteoporos Int, 2017;28(4):1473-1480.
  8. Xi L, Zhang H#, Zhang ZL#. Genotypic and Phenotypic Characteristics of 29 Patients With Rare Types of Osteogenesis Imperfecta: Average 5 Years of Follow-Up. Front Genet, 2021;12: 622078.
  9. Cao YJ, Zhang H#, Zhang ZL#. Novel mutations in the WNT1, TMEM38B, P4HB, and PLS3 genes in four unrelated Chinese families with osteogenesis imperfecta. Endocr Pract, 2019; 25(3):230-241.
  10. He J*, Zhang H*, Wang C, Zhang Z, Yue H, Hu W, Gu J, Fu W, Hu Y, Li M, Liu Y, Zheng H, Zhang Z.Associations of serum sclerostin and polymorphisms in the SOST gene with bone mineral density and markers of bone metabolism in postmenopausal Chinese women. J Clin Endocrinol Metab, 2014;99(4):E665-673.
  • Rank second, Shanghai Science and Technology Award, first prize 2012
  • Genetic mechanism and clinical application of osteoporosis and monogenic bone disease