Education:

• Doctor of Orthopedics, Shanghai Jiao Tong University, from September 2011 to June 2015
• Master of Surgery, Shanghai Second Medical University, from September 2001 to June 2004
• Bachelor of Clinical Medicine, Hubei College of Medicine, from September 1996 to June 2001

Profession:

• Chief Physician in Orthopedics, Shanghai Sixth People's Hospital, from January 2023 to present
• Associate Chief Physician in Orthopedics, Shanghai Sixth People's Hospital, from December 2016 to December 2022
• Attending Physician in Orthopedics, Shanghai Sixth People's Hospital, from July 2008 to November 2016
• Physician in Orthopedics, Shanghai Sixth People's Hospital, from July 2004 to June 2008

• Vice Leader of the Tumor Working Group, Orthopedic Physicians Branch, Shanghai Medical Association
• Vice Chairman of the Regenerative Medicine and Rehabilitation Professional Committee, Chinese Association of Rehabilitation Medicine
• Vice Chairman of the Bone and Cartilage Regeneration and Repair Professional Committee, Shock Wave Medicine Professional Committee, China Association of Research Hospitals
• Vice Leader of the Orthopedics Group, Professional Committee on Translational Medicine, Chinese Microcirculation Society
• Secretary of the Limb Study Group, Sarcoma Professional Committee, Chinese Anti-Cancer Association
• Member of the Bone Tumors and Bone Metastasis Professional Committee, Chinese Anti-Cancer Association
• Youth Member of the China Section, Asia-Pacific Microsurgery Alliance
• Member of the Bone Tumor Group, Professional Committee on Reconstructive and Plastic Surgery

1. Shu L, Lin S, Zhou S, Yuan T. Glycan-Lectin interactions between platelets and tumor cells drive hematogenous metastasis. Platelets. 2024 Dec;35(1):2315037.
2. Zhou L, Tang J, Shen L, Zhang Z, Yuan T. Giant cell tumors of the distal ulna: long-term recurrence rate and functional outcomes of en bloc resection versus curettage in a multicenter study. Journal of orthopaedic surgery and research. 2023 Sep 30;18(1):743.
3. Zhou L, Lin S, Jin H, Zhang Z, Zhang C, Yuan T. Preoperative CT for prediction of local recurrence after curettage of giant cell tumor of bone. J Bone Oncol. 2021 Aug;29:100366.
4. Lin S, Zhou L, Dong Y, Yang Q, Yang Q, Jin H, et al. Alpha-(1,6)-fucosyltransferase (FUT8) affects the survival strategy of osteosarcoma by remodeling TNF/NF-kappaB2 signaling. Cell Death Dis. 2021 Dec 2;12(12):1124.
5. Zhou L, Zhu H, Lin S, Jin H, Zhang Z, Dong Y, et al. Computerised tomography features of giant cell tumour of the knee are associated with local recurrence after extended curettage. International orthopaedics. 2022 Feb;46(2):381-90.
6. Lin S, Zhou S, Yuan T. The "sugar-coated bullets" of cancer: Tumor-derived exosome surface glycosylation from basic knowledge to applications. Clin Transl Med. 2020 Oct;10(6):e204.
7. Lin S, Miao Y, Zheng X, Dong Y, Yang Q, Yang Q, et al. ANGPTL4 negatively regulates the progression of osteosarcoma by remodeling branched-chain amino acid metabolism. Cell Death Discov. 2022 Apr 23;8(1):225.
8. Zhou L, Lin S, Zhu H, Dong Y, Yang Q, Yuan T. The blood pressure and use of tourniquet are related to local recurrence after intralesional curettage of primary benign bone tumors: a retrospective and hypothesis-generating study. BMC musculoskeletal disorders. 2022 Mar 3;23(1):201.
9. Zhu H, Jin H, Zhang C, Yuan T. Intestinal methicillin-resistant Staphylococcus aureus causes prosthetic infection via "Trojan Horse" mechanism: Evidence from a rat model. Bone & joint research. 2020;9(4):152-61.
10. Guo SC, Tao SC, Yin WJ, Qi X, Yuan T, Zhang CQ. Exosomes derived from platelet-rich plasma promote the re-epithelization of chronic cutaneous wounds via activation of YAP in a diabetic rat model. Theranostics. 2017;7(1):81-96.

• 01/01/2022-12/31/2024
  Project for Enhancing Medical Service Capacity of the Sixth Hospital of the City, Clinical Medical Technology Backbone Team Training Program, ¥60,000
  Analysis of the therapeutic effects of arthroscopic minimally invasive surgery combined with local infusion of polidocanol bone grafting in treating bone cysts in adolescents and children: A single-arm clinical trial with a historical control. 
  Role: Principal Investigator
• 01/01/2016-12/31/2019
  National Natural Science Foundation of China General Program, ¥570,000, No:81572239
  Study on the mechanism of selective activation of platelet membrane receptors intervening in tendon stem cell heterodifferentiation and its promotion of tendon disease repair.
  Role: Project leader

1.  Zhang C, Yuan T. Centrifuge apparatus for separating blood components. Patent No: US 10,286,140 B2 2019.

• Translation of research achievements: A centrifuge tube for preparing platelet-rich plasma ZL200420081020.8. 2004. Commercial conversion amount of the patent: 2,000,000RMB