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Research

YI Hongliang  

  • Doctoral Supervisor, Professor
  • Department: ENT & HN Surgery
  • Research Area: Otolaryngology
  • Research Interests: Diagnosis and treatment of obstructive sleep apnea-hypopnea syndrome; Diagnosis and treatment of  head and neck cancer
  • Contact: yihongl@126.com
Biography Positions Publications Patents
  • Bachelor's degree from Shanghai Second Medical University, 1995
  • Master's degree from Shanghai Second Medical University, 2005
  • PhD from Shanghai Jiao Tong University School of Medicine, 2008
  • Executive Deputy Director, Department of ENT and HN Surgery, Shanghai Sixth People's Hospital
  • Consultant, Laryngopharyngeal Group, Otorhinolaryngology Head and Neck Surgery Branch, Chinese Medical Association
  • Vice Chairman, Thyroid Specialist Committee, Society of Integrative Otolaryngology Head and Neck Surgery, Chinese Medical Association
  • Executive Director, Chinese Sleep Research Association
  • Deputy Group Leader, Throat Group, Otorhinolaryngology Head and Neck Surgery Society of Shanghai Medical Association
  • Deputy Group Leader, Throat Group, Otorhinolaryngology Head and Neck Surgery Branch, Shanghai Medical Association
  1. Wang, X., Zhou, T., Huang, W., Zhang, J., Zou, J., Guan, J., Yi, H.#, and Yin, S. (2024). Differences in physiological endotypes between non-positional and positional obstructive sleep apnea: Results from Shanghai Sleep Health Study cohort. Chest. 10.1016/j.chest.2024.01.021.
  2. Zhou, T., Huang, W., Wang, X., Zhang, J., Zhou, E., Tu, Y., Zou, J., Su, K., Yi, H.#, and Yin, S. (2024). Global burden of head and neck cancers from 1990 to 2019. iScience 27, 109282. 10.1016/j.isci.2024.109282.
  3. Zhou, T., Li, Z., Jiang, Y., Su, K., Xu, C., and Yi, H.# (2024). Emerging roles of circular RNAs in regulating the hallmarks of thyroid cancer. Cancer gene therapy. 10.1038/s41417-024-00736-0.
  4. Huang, W., Li, C., Zou, J., Wang, X., Zhang, J., Guan, J., Yi, H.#, and Yin, S. (2023). Effects of the combination of novel eye mask sleep position therapy device and oral appliance on positional OSA: A multi-arm, parallel-group randomized controlled trial. Sleep Medicine 102, 52–63. 10.1016/j.sleep.2022.12.017.
  5. Huang, W., Zhang, X., Wang, X., Zhou, T., Zhao, X., Xu, H., Li, X., Guan, J., Yi, H.#, and Yin, S. (2023). Effects of obstructive sleep apnea during rapid eye movement sleep on cardiac autonomic dysfunction: Results from the Shanghai sleep health study cohort. Journal of Sleep Research 32. 10.1111/jsr.13904.
  6. Huang, W., Zhang, J., Zou, J., Wang, X., Xu, H., Guan, J., Yi, H.#, Liu, S., and Yin, S. (2023). Fibroblast growth factor 21 is an independent predictor of prevalent and incident obstructive sleep apnea. iScience 26. 10.1016/j.isci.2023.105985.
  7. Jiao, X., Zou, J., Meng, L., Liu, S., Guan, J., Yi, H.#, and Yin, S. (2022). Risk factors for non-positional obstructive sleep apnea–hypopnea syndrome. Sleep and Breathing 26, 675–680. 10.1007/s11325-021-02430-z.
  8. Zhang, Q., Wang, X., Cheng, X., Wu, X., Feng, Y., Xu, H., Zhu, H., Yi, H.#, Zhang, W., and Li, X., et al. (2022). Multiple genetic variations of chronic rhinosinusitis with nasal polyps are associated with respiratory parameters in men with obstructive sleep apnea. Sleep and Breathing 26, 57–65. 10.1007/s11325-021-02356-6.
  9. Xu, H., Liu, F., Li, Z., Li, X., Liu, Y., Li, N., Zhang, X., Gao, Z., Zhang, X., and Yi, H., et al. (2022). Genome-Wide Association Study of Obstructive Sleep Apnea and Objective Sleep-related Traits Identifies Novel Risk Loci in Han Chinese Individuals. American journal of respiratory and critical care medicine 206, 1534–1545. 10.1164/rccm.202109-2044OC.
  10. Huang, W., Zhong, A., Xu, H., Xu, C., Wang, A., Wang, F., Li, X., Liu, Y., Zou, J., and Yi, H.#., et al. (2022). Metabolomics Analysis on Obesity-Related Obstructive Sleep Apnea After Weight Loss Management: A Preliminary Study. Frontiers in Endocrinology 12. 10.3389/fendo.2021.761547.
  11. Huang, W., Wang, X., Xu, C., Xu, H., Zhu, H., Liu, S., Zou, J., Guan, J., Yi, H.#, and Yin, S. (2022). Prevalence, characteristics, and respiratory arousal threshold of positional obstructive sleep apnea in China: a large scale study from Shanghai Sleep Health Study cohort. Respiratory Research 23. 10.1186/s12931-022-02141-3.
  12. Huang, W., Liu, Y., Wang, X., Li, X., Liu, Y., Zou, J., Xu, H., Zhu, H., Yi, H.#, and Guan, J., et al. (2021). Effect of interaction between slow wave sleep and obstructive sleep apnea on insulin resistance: A large-scale study. Nature and Science of Sleep 13, 739–749. 10.2147/NSS.S311130.
  13. Liu, Y., Huang, W., Zou, J., Xu, H., Qian, Y., Zhu, H., Meng, L., Guan, J., Yi, H.#, and Yin, S. (2021). Sea level nocturnal minimal oxygen saturation can accurately detect the presence of obstructive sleep apnea in a population with high pretest probability. Sleep and Breathing 25, 171–179. 10.1007/s11325-020-02014-3.
  14. Wang, X., Xu, C., Wang, S., Huang, W., Liu, Y., Zhang, X., Li, N., Gao, Z., Wang, F., and Yi, H.#, et al. (2021). A novel tumor suppressor CECR2 down regulation links glutamine metabolism contributes tumor growth in laryngeal squamous cell carcinoma. Clinical and Translational Oncology 23, 1942–1954. 10.1007/s12094-021-02603-y.
  15. Zhou, Q., Feng, J., Yin, S., Ma, S., Wang, J., and Yi, H.# (2021). LncRNA FAM230B promotes the metastasis of papillary thyroid cancer by sponging the miR-378a-3p/WNT5A axis. Biochemical and Biophysical Research Communications 546, 83–89. 10.1016/j.bbrc.2021.01.109.
  16. Song, Z., Guo, K., Huang, W., Xu, H., Liu, Y., Guan, J., Yin, S., Yu, H., Yi, H.#, and Zou, J. (2021). Decreased serum betatrophin may correlate with the improvement of obstructive sleep apnea after Roux-en-Y Gastric Bypass surgery. Scientific Reports 11. 10.1038/s41598-021-81379-1.
  17. Liu, Y., Zou, J., Qian, Y., Xu, H., Zhu, H., Meng, L., Guan, J., Yi, H.#, and Yin, S. (2021). The association between obesity indices and obstructive sleep apnea is modified by age in a sex-specific manner. Sleep and Breathing 25, 189–197. 10.1007/s11325-020-02083-4.
  18. Li, X., Fu, Z., Xu, H., Zou, J., Zhu, H., Li, Z., Su, K., de Huai, Yi, H.#, and Guan, J., et al. (2020). Influence of multiple apolipoprotein A-I and B genetic variations on insulin resistance and metabolic syndrome in obstructive sleep apnea. Nutrition and Metabolism 17. 10.1186/s12986-020-00501-8.
  19. Qian, Y., Zou, J., Xu, H., Zhu, H., Meng, L., Liu, S., Yi, H.#, Guan, J., and Yin, S. (2020). Association of upper airway surgery and improved cardiovascular biomarkers and risk in OSA. Laryngoscope 130, 818–824. 10.1002/lary.28012.
  20. Jia, P., Zou, J., Yin, S., Chen, F., Yi, H.#, and Zhang, Q. (2020). Analysis of the Salivary Microbiome in Obstructive Sleep Apnea Syndrome Patients. Canadian Journal of Infectious Diseases and Medical Microbiology 2020. 10.1155/2020/6682020.
  21. Song, F., Zou, J., Song, Z., Xu, H., Qian, Y., Zhu, H., Liu, S., Guan, J., Chen, J., and Yi, H.# (2020). Association of Adipocytokines With Carotid Intima Media Thickness and Arterial Stiffness in Obstructive Sleep Apnea Patients. Frontiers in Endocrinology 11. 10.3389/fendo.2020.00177.
  22. Huang, W., Liu, Y., Xu, H., Zhu, H., Guan, J., Yi, H.#, and Zou, J. (2020). Association of the serum Irisin level with obstructive sleep apnea: A body mass index-and physical activity-matched study. Endocrine Journal 67, 607–612. 10.1507/endocrj.EJ19-0590.
  23. Li, X., Huang, H., Xu, H., Shi, Y., Qian, Y., Zou, J., Yi, H.#, Guan, J., and Yin, S. (2019). Excessive daytime sleepiness, metabolic syndrome, and obstructive sleep apnea: Two independent large cross-sectional studies and one interventional study. Respiratory Research 20. 10.1186/s12931-019-1248-y.
  24. Xu, H., Zhao, X., Shi, Y., Li, X., Qian, Y., Zou, J., Yi, H.#, Huang, H., Guan, J., and Yin, S. (2019). Development and validation of a simple-to-use clinical nomogram for predicting obstructive sleep apnea. BMC pulmonary medicine 19, 18. 10.1186/s12890-019-0782-1.
  1. [Yi Hongliang*; Yin Shankai; Guan Jian; Zhang Yujun; Liu Suru; Liu Yupu; Zhou Jianrong](2013),"A CT head positioning frame", ZL 201320491390.8
  2. [Hou Limin; Zhang Changheng; Yin Shankai; Yi Hongliang*; Meng Lili](2014),"A device for screening OSAHS based on snoring", ZL201410000686
  3. [Hou Limin; Yin Shankai; Xie Su; Yi Hongliang*; Meng Lili](2014),"A method for determining the site of upper airway narrowing or obstruction in OSAHS patients based on snoring", ZL201310376181

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