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YAN Xiaoyu
- Chief Physician, Doctoral Supervisor
- Department: Orthopedics
- Research Area: Sports Medicine Orthopeadics Biomaterial
- Research Interests: Treatment of sports Injuries Basic and clinical research on structural and functional reconstruction of Limb Bones and Joints Wound Healing and Tissue Repair Research and development and application of active biomaterials for tissue and wound repair
- Contact: yanorth@126.com
- Fellowship, Duke Medical Center, Duke University, USA, 2014
- Fellowship, Department of Orthopaedics, Georg-August University of Göttingen, Germany, 2015
- MD from Tongji University School of Medicine, 2005
- PhD from Shanghai Jiao Tong University, 2008
- Yan D, Cao G, Gao Y, Wang Y, Zhang W, Wang K, Mao S, Li C, Zhou G, Huitang Xia*; Wufei Dai*; Xiaoyu Yan*; Yibing Wang*. Photothermal-Controlled Microneedle for Transdermal Delivery of Metal-Phenolic Nanozyme with Staged Multifunctions to Accelerate Healing of Infected Diabetic Wounds. Materials Today Bio, 2025, 101554 .doi: 10.1016/j.mtbio.2025.101554.
- Zhang, Guoyang; Shi, Dingyi; Wei, Yiyao; Wang, Mingqi; Wang, Haohan; Lin, Zhiqi; Gao, Haihan; Lin, Weixuan; Wang, Hanyi; Guo, Yonglin; Ge, Yingyu; Lin, Yi; Jiang, Yiwen; Yan, Xiaoyu*; Kang, Yuhao*; Wang, Liren*; Zhao, Jinzhong*; Ying, Weiyang*. Drug-free extracellular vesicles: A spatiotemporally controlled release engineering strategy for osteogenesis and anti-inflammatory niches in rotator cuff regeneration Composites Part B: Engineering, 2025, 288. DOI: 10.1016/j.compositesb.2024.111928
- Zhang G, Kang Y, Dong J, Shi D, Xiang Y, Gao H, Lin Z, Wei X, Ding R, Fan B, Zhang H, Zhu T, Wang L, Yan X.Fluffy hybrid nanoadjuvants for reversing the imbalance of osteoclastic and osteogenic niches in osteoporosis.Bioactive Materials, 2024, 39: 354–374.doi: 10.1016/j.bioactmat.2024.05.037. .
- Yu Xiang; Beibei Fan; Panpan Shang; Ren Ding; Juan Du; Tonghe Zhu; Hongmei Zhang*; Xiaoyu Yan*.VR23 and Bisdemethoxycurcumin Enhanced Nanofiber Niche with Durable Bidirectional Functions for Promoting Wound Repair and Inhibiting Scar Formation. Small Methods, 2024, 8(12). doi: 10.1002/smtd.202400273.
- Chen Y, Xiang Y, Zhang H, Zhu T, Chen S, Li J, Juan Du*; Xiaoyu Yan*. A multifunctional chitosan composite aerogel based on high density amidation for chronic wound healing. Carbohydrate Polymers, 2023 . doi: 10.1016/j.carbpol.2023.121248. .
- Yao Chen; Yu Xiang; Tonghe Zhu*; Sihao Chen; Juan Du; Jiajia Luo; Xiaoyu Yan*. A dZnONPs Enhanced Hybrid Injectable Photocrosslinked Hydrogel for Infected Wounds Treatment. Gels, 2022, 8(8): 463–463. doi: 10.3390/gels8080463.
- Wang L, Kang Y, Xie G, Cai J, Chen C, Yan X, Jiang J, Zhao J. Incomplete Rotator Cable Did Not Cause Rotator Cuff Dysfunction in Case of Rotator Cuff Tear: A Biomechanical Study of the Relationship Between Rotator Cable Integrity and Rotator Cuff Function. Arthroscopy: The Journal of Arthroscopic & Related Surgery, 2021, 37(8): 2444–2451 .doi: 10.1016/j.arthro.2021.03.051. .
- Khan AUR, Huang K, Jinzhong Z, Zhu T, Morsi Y, Aldalbahi A, El-Newehy M, Xiaoyu Yan*; Xiumei Mo*. Exploration of the antibacterial and wound healing potential of a PLGA/silk fibroin based electrospun membrane loaded with zinc oxide nanoparticles. Journal of Materials Chemistry B, 2021, 9: 1452–1465. doi: 10.1039/d0tb02822c. .
- Khan AUR, Huang K, Jinzhong Z, Zhu T, Morsi Y, Aldalbahi A, El-Newehy M, Xiaoyu Yan*; Xiumei Mo*. PLCL/silk fibroin based antibacterial nano wound dressing encapsulating oregano essential oil: Fabrication, characterization and biological evaluation. Colloids and Surfaces B: Biointerfaces, 2020, 196.doi: 10.1016/j.colsurfb.2020.111352.
- 01/2026–12/2029
National Natural Science Foundation of China (General Program), ¥ 550,000,
Effects and mechanisms of a microneedle patch dynamically targeting mitochondrial function for multi-target repair of diabetic wounds.
Role: Principal Investigator - 01/2022–12/2025
National Natural Science Foundation of China (General Program), ¥550,000,
Experimental study on in situ personalized construction of an adaptive composite to regulate wound microenvironment and promote angiogenesis for repair of infected defect wounds.
Role: Principal Investigator
