Graduate Supervisor, Associate Professor, Associate Chief Physician
Department: Neurology
Research Area:
Neurology
Research Interests:
Basic and clinical research of stroke, traumatic brain injury, eplilepsy and Alzheimer's disease; artificial intelligence in epilepsy
Medical Doctoral Degree from Shanghai Jiao Tong University Shcool of Medicine, 2023
Master's Degree from Shanghai Jiao Tong University Shcool of Medicine, 2008
Bachelor's Degree in Clinical Medicine from Changzhi Medical College, 2004
Member of Chinese Stroke Association (CSA)
Member of China Association Against Epilepsy (CAAE)
Member of Shanghai Stroke Association (SSA)
Member of International Brain Injury Association (IBIA)
Xue LX#, Shu LY#, Wang HM, Lu KL, Huang LG, Xiang JY, Geng Z, Zhao YW, Chen H*. miR-181b promotes angiogenesis and neurological function recovery after ischemic stroke. Neural Regen Res, 2023, 18(9):1983-1989. doi: 10.4103/1673-5374.367957.
Chen H#, Gong Y, Ma Y, Thompson RC, Wang J, Cheng Z*, Xue L*. A Brain-Penetrating Hsp90 Inhibitor NXD30001 Inhibits Glioblastoma as a Monotherapy or in Combination With Radiation. Front Pharmacol, 2020, 11:974. doi: 10.3389/fphar.2020.00974.
Xue L#, Huang J, Zhang T, Wang X, Fu J, Geng Z, Zhao Y, Chen H*. PTEN inhibition enhances angiogenesis in an in vitro model of ischemic injury by promoting Akt phosphorylation and subsequent hypoxia inducible factor-1α upregulation. Metab Brain Dis, 2018, 33(5):1679-1688. doi: 10.1007/s11011-018-0276-5.
Xue L#, Chen H, Zhang T, Chen J, Geng Z, Zhao Y*. Changes in serum vascular endothelial growth factor and endostatin concentrations associated with circulating endothelial progenitor cells after acute ischemic stroke. Metab Brain Dis, 2017, 32(2):641-648. doi: 10.1007/s11011-017-9953-z.
Xue L#, Chen H, Lu K, Huang J, Duan H, Zhao Y*. Clinical significance of changes in serum neuroglobin and HIF-1α concentrations during the early-phase of acute ischemic stroke. J Neurol Sci, 2017, 375:52-57. doi: 10.1016/j.jns.2017.01.039.
Xue L#, Zhang T, Zhao Y, Geng Z, Chen J, Chen H*. Efficacy and safety comparison of DL 3 n butylphthalide and Cerebrolysin: Effects on neurological and behavioral outcomes in acute ischemic stroke. Exp Ther Med, 2016, 11(5):2015-2020. doi: 10.3892/etm.2016.3139.
Chen H#, Cao H#, Chen S, Guo Y, Gao W, Tian H, Xue L*. Neuroglobin and Nogo-a as biomarkers for the severity and prognosis of traumatic brain injury. Biomarkers, 2015, 20(6-7):495-501. doi: 10.3109/1354750X.2015.1094138.
Chen H#, Xue L#, Guo Y, Chen S, Wang G, Cao H, Chen J, Tian HL*. The influence of hemocoagulation disorders on the development of posttraumatic cerebral infarction and outcome in patients with moderate or severe head trauma. Biomed Res Int, 2013, 2013:685174. doi: 10.1155/2013/685174.
Chen H#, Xue L#, Cao H, Chen S, Guo Y, Gao W, Ju S, Tian HL*. Endostatin/Collagen XVIII is increased in cerebrospinal fluid after severe traumatic brain injury. Biomed Res Int, 2013, 2013:402375. doi: 10.1155/2013/402375.
[Hao Chen, Yunlei Wang, Lixia Xue, Kenan Wang, Shi Wang, Jiong Zhou] (2022), “An adjustable working channel for neuroendoscopic surgery”, PCT/CN218165299U, ZL202220382891.1
[Hao Chen, Lixia Xue, Jun Ding, Jiong Chen, Yuhui Cui, Fang Yuan] (2023), “A combination for reducing intracranial pressure and its usage method”, PCT/CN116236547B; ZL202310334502.7
[Hao Chen, Lixia Xue, Jiong Chen, Jiong Zhou] (2024), “An lumbar drainage system for intracranial pressure monitoring”, PCT/CN202420108461.X
[Hao Chen, Yuqing Liang, Lixia Xue, Lai Wei] (2024), “A preparation method and application of nanoparticles targeting brain injury sites for the treatment of traumatic brain injury”, PCT/CN2024101878017