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WEN Gen
- Graduate Supervisor, Associate Chief Physician
- Department: Orthopedics
- Research Area: Surgery (Orthopedics)
- Research Interests: Biomarterials; Limb defect repair
- Contact: wengen2006@126.com
- Bachelor's degree in Medicine from Sichuan University, 2007
- Master's degree in Medicine from Soochow University, 2010
- Doctoral degree in Medicine from Soochow University, 2020
- Associate Chief Physician, Department of Orthopedics, Shanghai Sixth People's Hospital
- Member, 11th Committee of the Microsurgery Branch of Chinese Medical Association
- Biomimetic hydrogel derived from decellularized dermal matrix facilitates skin wounds healing,Mater Today Bio,2023 Jul 7:21:100725. doi: 10.1016/j.mtbio.2023.100725;
- A spatiotemporal release hydrogel based on an M1-to-M2 immunoenvironment for wound management,J Mater Chem B,2023 May 10;11(18):3994-4004. doi: 10.1039/d3tb00463e;
- Identification and comprehensive analysis of circRNA-miRNA-mRNA regulatory networks in osteoarthritis,Front Immunol,2023 Jan 9:13:1050743. doi: 10.3389/fimmu.2022.1050743.;
- Tumor necrosis factor-α promotes Staphylococcus aureus-induced osteomyelitis through downregulating endothelial nitric oxide synthase.2021 Dec;54(6):1018-1027. doi: 10.1016/j.jmii.2020.08.002.;
- Human nail bed extracellular matrix facilitates bone regeneration via macrophage polarization mediated by the JAK2/STAT3 pathway.J Mat Chem B,2020 May 14;8(18):4067-4079. doi: 10.1039/c9tb02910a.;
- Functionalized Polycaprolactone/Hydroxyapatite Composite Microspheres for Promoting Bone Consolidation in a Rat Distraction Osteogenesis Model. J Orthop Res.2020 May;38(5):961-971. doi: 10.1002/jor.24542. Epub 2019 Dec 5.;
- Human nail bed-derived decellularized scaffold regulates mesenchymal stem cells for nail plate regeneration. J Tissue Eng Regen Med.J Tissue Eng Regen Med,2019 Oct;13(10):1770-1778. doi: 10.1002/term.2927..
- 01/01/2019-12/31/2021
National Natural Science Foundation of China, Young Scientist Foundation of China,¥210,000, 81802156
Role and mechanism of SDF-1@MSNs doped porous corn protein scaffold in long bone regeneration
Role: Principal Investigator - 05/01/2018-04/30/2021
Shanghai Municipal Science and Technology Commission, General Project, ¥150,000, 18140901402
LNX2 Knockout Mouse Model Building
Role: Project leader - 07/01/2020-06/30/2023
Ministry of Science and Technology of the People's Republic of China, National Key R&D Program of China, ¥1,760,000,2020YFC2004906,
Key Technology Breakthrough and Equipment R&D for Ladder Treatment of Geriatric Skeletal System Degeneration,
Role: Project leader
- [Gen Wen, Xuhua Wu] (2016), “A multi-axis adjustable migration external fixation bracket”, ZL201620619393.9
- [Gen Wen, Xuhua Wu] (2018), “Multi-axis adjustable migration of external fixation brackets”, ZL201610451663.4
- [Yimin Chai, Xuhua Wu, Gen Wen, Jia Xu] (2020), “An external fixator that promotes bone growth”, ZL201920688866.4
- [Gen Wen] (2023), “Knee osteoarthritis auxiliary detector”, CN308293797S
- [Gen Wen] (2023), “A wearable sensor device for auxiliary detection of knee osteoarthritis”, CN219940612U
- Gen Wen(12/15).Innovation and application of key technologies for the repair and reconstruction of complex tissue defects of limbs, China Association for the Promotion of International Exchange in Health Care
