WAN Xinjian  

  • Chief Physician, Doctoral Supervisor, Professor
  • Department: Digestive Endoscopic Center
  • Research Area: Internal Medicine (Digestive Diseases)
  • Research Interests: Pathogenesis and endoscopic management of  bile duct stones
  • Contact: slwanxj2019@163.com
  • Fellowship, Digestive Endoscopic Center of Memorial Hospital of Northwestern University and Emory University Hospital, USA, 2011
  • Fellowship, Digestive Endoscopic Center of Kyushu University Hospital, Japan, 2008
  • PhD and MD from Changhai Hospital Affiliated to the Second Military Medical University, 1999
  • MPH from Changhai Hospital Affiliated to the Second Military Medical University, 1996
  • Director, Digestive Endoscopic Center, Shanghai Sixth People's Hospital
  • Standing Committee Member, Chinese Endoscopist Association of CMDA
  • Committee Member, Chinese Association of Gastroenterologist and Hepatologist
  • Committee Member, Endoscopy Committee of the Chinese Anti-Cancer AssociationStanding Committee Member, Chinese Research Hospital Association for Budd-Chiari Syndrome and Liver Vascular Disease
  • Committee Member, Digestive Endoscopy Committee of CMDA
  • Committee Member, Endoscopic Quality Control and Management Committee of CMDA
  • Director,Shanghai Medical Association
  • Appointed Chairman, Esophageal and Gastric Varicocele Treatment Professional Committee of the Shanghai Medical Association
  • Vice Chairman, Tumor Endoscopy Committee of Shanghai Anti-Cancer Association
  • Committee Member, Digestive Endoscopy Branch of Shanghai Medical Association
  • Deputy Leader, ERCP Group of Shanghai Digestive Endoscopy Society
  • Committee Member, Shanghai Digestive Endoscopy Quality Control Expert Committee
  • Editorial Board Member, Chinese Journal of Digestive Endoscopy
  1. Song Wang, Zhixia Dong, Xinjian Wan# Zhang S, Li S, Wang W#.Global, regional, and national burden of inflammatory bowel disease and its associated anemia, 1990 to 2019 and predictions to 2050: An analysis of the global burden of disease study 2019. Autoimmunity Reviews, 2023, doi: 10.1016/j.autrev.2023.103498.  
  2. Jianbo Ni, Kui Peng, Lanting Yu, Haoran Xie, Shengzheng Luo, Kai Xu, Youchen Xia, Ni Xie, Jiawei Lu, Lungen Lu, Duanmin Hu, Xinjian Wan#, Baiwen Li. Transpapillary Stenting Improves Treatment Outcomes in Patients Undergoing Endoscopic Transmural Drainage of Ductal Disruption-Associated Pancreatic Fluid Collections. 2023. American Journal of Gastroenterology, doi: 10.14309/ajg.0000000000002083.
  3. Haiming Zheng, Meiying Zhu, Wenhua Li, Zunqiang Zhou, Xinjian Wan#.m5 C and m6 A modification of long noncoding NKILA accelerates cholangiocarcinoma progression via the miR-582-3p-YAP1 axis. Liver international : official journal of the International Association for the Study of the Liver, 2023, doi: 10.1111/liv.15240.
  4. Xin Ye, Dan Huang , Zhixia Dong, Min Ning, Jie Xia, Shuang Shen, Shan Wu, Yan Shi, Jingjing Wang, Xinjian Wan#.FXR Signaling-Mediated Bile Acid Metabolism Is Critical for Alleviation of Cholesterol Gallstones by Lactobacillus Strains. Microbiology Spectrum, 2022, doi: 10.1128/spectrum.00518-22.
  5. Zhixia Dong, Jie Xia, Xinjian Wan#. A rare helicobacter pylori infection-negative early gastric cancer in a young man with primary hypertrophic osteoarthropathy. Endoscopy, 2022, doi: 10.1055/a-1722-2336.
  6. Qian Zhuang, Jinnian Cheng, Jie Xia, Min Ning, Shan Wu, Shuang Shen, Yan Shi, Dan Huang, Zhixia Dong, Xinjian Wan#. Gypenosides Prevent and Dissolve Cholesterol Gallstones by Modulating the Homeostasis of Cholesterol and Bile Acids. Frontiers in medicine, 2022, doi: 10.3389/fmed.2022.818144
  7. Qian Zhuang, Xin Ye, Shuang Shen, Jinnian Cheng, Yan Shi, Shan Wu, Jie Xia, Min Ning, Zhixia Dong, Xinjian Wan#. Astragalus Polysaccharides Ameliorate Diet-Induced Gallstone Formation by Modulating Synthesis of Bile Acids and the Gut Microbiota. Frontiers in pharmacology, 2021, doi: 10.3389/fphar.2021.701003.
  8. Xin Ye, Shuang Shen, Zhengjie Xu, Qian Zhuang, Jingxian Xu, Jingjing Wang, Zhixia Dong, Xinjian Wan#. Sodium butyrate alleviates cholesterol gallstones by regulating bile acid metabolism. European journal of pharmacology 2021, doi: 10.1016/j.ejphar.2021.174341.
  9. Xiao Bo Cai, Wei Xing Zhang, Ru Ling Zhang, Xiao Dong Yuan, Qin Yang, Xiao Shen Qi, Bai Wen Li, Yue Qin Qian, Xing Peng Wang, Lun Gen Lu, Zheng Jie Xu, Xin Jian Wan. Safety and efficacy of a novel plastic stent coated with stone-dissolving agents for the treatment of biliary stones in a porcine model. 2015, doi: 10.1055/s-0034-1390772.
  10. Jingbo Xiao, Junyong Weng, Yang-Yang Hu, Guilong Deng, Xinjian Wan#. Feasibility and efficacy evaluation of metallic biliary stents eluting gemcitabine and cisplatin for extrahepatic cholangiocarcinoma. World Journal of Gastroenterology, 2020, doi: 10.3748/wjg.v26.i31.4589 
  1. [Wan Xinjian,Zhang Weixing](2023) “Electrospun nanofiber membrane and esophageal coated memory scaffold with controlled release of growth factors”, PCT/CN 2023/11/21; CN109172073B
  2. [Wan Xinjian](2021) “A protective head mask for transoral endoscopic operation”, PCT/CN 2021/08/27]; CN214047640U
  3. [Wan Xinjian, Zhang Weixing](2019) “A memory stent graft for the treatment of esophageal injury without stricture or obstruction”, PCT/CN 2019/10/11; CN209474880U
  4. [Wan Xinjian, He Chongxin](2019) “Photosensitizer stents for the treatment of cholangiocarcinoma with photodynamic therapy”, PCT/CN 2019/09/10; CN209361439U
  5. [Wan Xinjian, Zhuang Qian](2019) “Novel fixed, retrievable, and anti-displacement esophageal metal stent”, PCT/CN 2019/08/27; CN209301410U
  6. [Wan Xinjian, Huang Chao](2019) “Endoscopic local grafted bile duct sampling metal stent”, PCT/CN 2019/07/26; CN209153778U
  7. [Wan Xinjian, Zhang Weixing](2019) “An Electrospun Nanofiber Membrane and Esophageal Coated Memory Scaffold with Controlled Release Growth Factor”, PCT/CN 2019/01/11; CN109172073A
  8. [Wan Xinjian, Huang Chao](2018). “An endoscopic metal stent for sampling bile ducts with local membrane grafting”, PCT/CN 2018/12/21;CN109044415A
  9. [Wan Xinjian, Zhuang Qian](2018) “A Novel Fixed, Retrievable, and Anti-Displacement Esophageal Metal Stent”, PCT/CN 2018/11/30; CN108904106A
  10. [Wan Xinjian, He Chongxin](2018) “A photosensitizer stent that can be used for photodynamic therapy in the treatment of cholangiocarcinoma”, PCT/CN 2018/11/2; CN108888808A

Scientific Achievements:

  • "A Self-expanding Metal Mesh Sampling Device", May 2012, the 24th Shanghai Outstanding Invention Contest Outstanding Invention Bronze Award, primary completer
  • "R&D and Application of Monofilament Mesh Structure Digestive Tract Metal Stents", 2012, Second Prize of Science and Technology Progress Award of the Ministry of Education, Certificate No.: 2011-263, the fourth completer
  • "Application and Promotion of Radioactive Stents for Digestive Tract and Pancreaticobiliary Duct", 2010, First Prize of Enders Medical Science and Technology Award, GPA20101029102, the second completer