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SONG Lujie  

  • Chief Physician, Doctoral Supervisor
  • Department: Urology
  • Research Area: Surgery (Urology)
  • Research Interests: Urinary tract repair and reconstruction
  • Contact: ljsong@sjtu.edu.cn
Biography Positions Publications Patents Other
  • Clinical Observation, Urology Clinics, UCSF Medical Center, 2018
  • Visiting Scholar, Wake Forest Institute for Renerative Medicine, 2013
  • PhD from Shanghai Jiao Tong University School of Medicine, 2008
  • Master's Degree from Shandong Second Medical University, 2005
  • Bachelor's Degree from Shandong Second Medical University, 2002
  • Associate director, Department of Urology, Shanghai Sixth People's Hospital
  • Active Member of the Society of Genitourinary Reconstructive Surgeons(GURS)
  • Standing Member of the Surgery Branch of Chinese Sexology Society
  • Member of the Branch of Andrology and Sexual Medicine of the Chinese Medical Association
  • Member of the Male Science Branch of Shanghai Medical Association
  • Vice Chairman of Urology Branch of Xuhui District Medical Association, Shanghai
  • Member of the Genitourinary Branch of China Association for the Promotion of International Communication of Medical and Health Care
  • Secretary, Urinary Tract Repair and Reconstruction Group, Urology Branch of Chinese Medical Association (CUDA)
  • Member of the Andrology Branch of Shanghai Medical Doctor Association 
  • Correspondence Editorial Board of "Chinese Journal of Urology" 
  • Editorial Board of International Neurourology Journal
  • The Youth Member of Aisan Association of Andrology
  1. Hou C, Gu Y, Yuan W, Zhang W, Xiu X, Lin J, Gao Y, Liu P, Chen X, Song L(corresponding author). Construction of a three-dimensional urothelium on-chip with barrier function based on urinary flow microenvironment. Biofabrication. 2023 Apr 11;15(3).
  2. Lujie Song; Kunxue Deng; Wei Yuan; Jing Zhang; Jiahao Lin; Xiaoyong Hu; Jianwen Huang; Kaile Zhang; Haitao Zhang; Jiemin Si; Hongbin Li; Tao Xu; Qiang Fu ; Anterior substitutional urethroplasty using a biomimetic poly-L-lactide nanofiber membrane: Preclinical and clinical outcomes, Bioengineering & Translational Medicine, 2022.
  3. Hou C, Gu Y, Yuan W, Zhang W, Xiu X, Lin J, Gao Y, Liu P, Chen X, Song L(corresponding author). Application of microfluidic chips in the simulation of the urinary system microenvironment. Mater Today Bio. 2023 Jan 20;19:100553.
  4. Hou C, Gu Y, Yuan W, Wang Z, Lin J, Fu Q, Song L(corresponding author). Diagnosis and treatment of anterior urethral strictures in China: an internet-based survey. BMC Urol. 2021 Dec 31;21(1):185. 
  5. Zeyu Wang; Tao Liang; Guoping Song; Jiahao Lin; Yunfeng Xiao; Feixiang Wang; Kaile Zhang; Jiong Zhang; Yuemin Xu; Qiang Fu; Lujie Song(corresponding author); The effects of primary realignment or suprapubic cystostomy on prostatic displacement in patients with pelvic fracture urethral injury: a clinical study based on MR urethrography., Injury, 2022, 53(2): 534-538.
  6. Wei Yuan; Yubo Gu; Kaile Zhang; Tao Liang; Ping Wang; Jiong Zhang; Yuemin Xu; Qiang Fu; Lujie Song(corresponding author); Postoperative Infection of Male Posterior Urethral Stenosis with Pelvic Fracture: A Retrospective Study from a Chinese Tertiary Teferral Center., Urology, 2021, 154: 294-299.
  7. Hou C, Lin J, Gu Y, Yuan W, Wang Z, Xiu X, Fu Q, Song L(corresponding author). The treatment practices for anterior urethral strictures in China: A case-based survey. Front Surg. 2022 Jul 27;9:863463. 
  8. Zhuang, Ao; Pan, Qichao; Qian, Ying; Fan, Suna; Yao, Xiang; Song, Lujie (corresponding author); Zhu, Bo; Zhang, Yaopeng.Transparent Conductive Silk Film with a PEDOT-OH Nano Layer as an Electroactive Cell Interface.ACS biomaterials science & engineering.2021-Feb-18.DOI:10.1021/acsbiomaterials.0c01665.
  9. Song L, Zhang R, Lu C, Chen Y. Factors to Consider in Augmentation Urethroplasty with Oral Mucosa Graft or Penile Skin Flap for Anterior Urethral Stricture: A Systematic Review and Meta-analysis. Eur Urol Open Sci. 2023 Mar 9;50:113-122.
  10. Zhang D#, Hou J#, Gu Y#, Shao J, Zhou S, Zhuang J, Song L*, Wang X*. Cryopreserved skin epithelial cell sheet combined with acellular amniotic membrane as an off-the-shelf scaffold for urethral regeneration. Mater Sci Eng C Mater Biol Appl. 2021 Mar;122:111926
  11. Suna Fan, Kai Chen, Wei Yuan, Dongliang Zhang, Siqing Yang, Ping Lan, Lujie Song (corresponding author), Huili Shao, and Yaopeng Zhang. Biomaterial-Based Scaffolds as Antibacterial Suture Materials. ACS Biomater Sci Eng. 2020 6 (5), 3154-3161.
  12. Liu Y, Huang L, Yuan W, Zhang D, Gu Y, Huang J, Murphy S, Ali M, Zhang Y, Song L (corresponding author). Sustained release of stromal cell-derived factor-1 alpha from silk fibroin microfiber promotes urethral reconstruction in rabbits. J Biomed Mater Res A. 2020 Aug 1;108(8):1760-1773. 
  13. Wang Z, Song G, Xiao Y, Liang T, Wang F, Gu Y, Zhang J, Xu Y, Jin S, Fu Q, Song L (corresponding author). The value of MRI geometric parameters in pre-assessing the surgical approaches of pelvic fracture urethral injury. Transl Androl Urol 2020 Dec;9(6):2596-2605.
  14. Zhang DL, Chen Z, Wang FX, Zhang J, Xie H, Wang ZY, Gu YB, Fu Q, Song LJ (corresponding author). Adding a vacuum erection device to regular use of Tadalafil improves penile rehabilitation after posterior urethroplasty. Asian J Androl. 2019, 21(6):582-586.
  15. Cao NL(Co-first author)#, Song LJ (Co-first author)#, Liu WJ, Fan SN, Jiang D, Mu JG, Gu BJ, Xu YM, Zhang YP(corresponding author)*, Huang JW(corresponding author)*, Prevascularized bladder acellular matrix hydrogel/silk fibroin composite scaffolds promote the regeneration of urethra in a rabbit model, Biomed. Mater. 14 (2019) 015002.
  16. Zhang YP (Co-first author)#*, Huang JW(Co-first author)#, Huang L, Liu QQ, Shao HL, Hu XC, Song LJ(corresponding author), Silk Fibroin-Based Scaffolds with Controlled Delivery Order of VEGF and BDNF for Cavernous Nerve Regeneration, ACS Biomater. Sci. Eng., 2016, 2 (11), 2018–2025. 
  17. Huang JW, Xie MK, Zhu WD, Qiang Fu, Xu YM, Song LJ(corresponding author). Tissue Performance of Bladder following Stretched Electrospun Silk Fibroin Matrix and Bladder Acellular Matrix implantation in a Rabbit Model. J Biomed Mater Res A. 2016 Jan;104(1):9-16.
  18. Liu QQ, Huang JW, Shao HL, Song LJ(corresponding author), Zhang YP(corresponding author). Dual-factor loaded functional silk fibroin scaffolds for peripheral nerve regeneration with the aid of neovascularization. RSC Adv. 2016; 6（9）: 7683-7691.
  19. Song L, Zhu J, Zhang X, Cui Z, Fu Q, Huang J, Lu H: BDNF-hypersecreting human umbilical cord blood mesenchymal stem cells promote erectile function in a rat model of cavernous nerve electrocautery injury. Int Urol Nephrol 2016 Jan;48(1):37-45.
  20. Zhu JQ, Lu HK, Cui ZQ, Wang YC, Li YH, Zhao W, Fu Q, Xu YM, Xu Y, Song LJ (corresponding author): Therapeutic potential of human umbilical cord blood mesenchymal stem cells on erectile function in rats with cavernous nerve injury. Biotechnol Lett. 2015 Jul;37(7):1515-25. 
  21. Song LJ, Murphy SV, Yang B, Xu Y, Zhang Y, Atala A. Bladder Acellular Matrix and Its Application in Bladder Augmentation. Tissue Eng Part B Rev 2014 Apr;20(2):163-72
  22. Huang JW, Xie MK, Zhang Y, Wei GJ, Li X, Li HB, Wang JH, Zhu WD, Li C, Xu YM, Song LJ (corresponding author). Reconstruction of penile urethra with the 3-dimensional porous bladder acellular matrix in a rabbit model. Urology. 2014; 84: 1499-1505. 
  23. Song LJ, Zhu JQ, Xie MK, Wang YC, Li HB, Cui ZQ, Lu HK, Xu YM. Electrocautery-induced cavernous nerve injury in rats that mimics radical prostatectomy in humans. BJU int. 2014; 114(1): 133-9
  24. Song LJ, Xie MK, Zhang YY, Xu YM: Imaging techniques for the diagnosis of male traumatic urethral strictures. J Xray Sci Technol 2013, 21(1):111-123.
  25. Song LJ, Lu HK, Wang JP, Xu YM. Cadaveric study of nerves supplying the membranous urethra. Neurourol Urodyn 2010, 29(4):592-595.
  26. Song LJ, Xu YM, Li C, Fu Q, Cui L, Hu XY. Construction of cavernosum smooth muscle using umbilical artery smooth muscle cells seeded on acellular corporal collagen matrices. Int J Androl 2009, 32(5):514-523.
  27. Song LJ, Xu YM, Lazzeri M, Barbagli G: Lingual mucosal grafts for anterior urethroplasty: a review. BJU Int 2009, 104(8):1052-1056. 
  28. Song LJ, Xu YM, Hu XY, Zhang HZ: Urethral substitution using autologous lingual mucosal grafts: an experimental study. BJU Int 2008, 101(6):739-743.
  29. Xu YM, Song LJ(Co-first author), Wang KJ, Lin J, Sun G, Yue ZJ, Jiang H, Shan YX, Zhu SX, Wang YJ et al: Changing trends in the aetiology and management of male urethral stricture disease in China: an observational descriptive study from 13 centres. BJU int 2015 Dec;116(6):938-44. 
  30. Xie M, Song L(Co-first author), Wang J, Fan S, Zhang Y, Xu Y: Evaluation of stretched electrospun silk fibroin matrices seeded with urothelial cells for urethra reconstruction. J Surg Res 2013, 184(2):774-781. 
  31. Shen T, Song LJ(Co-first author), Xu YM, Gu BJ, Lu LH, Li F: Sexual function and health-related quality of life following anterior vaginal wall surgery for stress urinary incontinence and pelvic organ prolapse. Int J Impot Res 2011, 23(4):151-157.
  1. [Song Lujie; Gu Yubo] (2021), “Suture-guided urethral probe”; ZL201920755543.2
  2. [Song Lujie; Gu Yubo] (2021), “A pressure bandage for perineal surgery”; ZL202020384654.X
  3. [Song Lujie; Gu Yubo] (2021), “Urinary catheterization device”; ZL 2022 2 3555557.0
  4. [Song Lujie; Gu Yubo] (2021), “A visual dilated urethral probe with pressure sensing device”; ZL 2022 2 2643801.2
  5. [Zhang Yaopeng, Song Lujie, Huang Jianwen, Shao Huili, Fu Qiang, Jiang Dan, Hu Xuechao] (2016), “Biomimetic tissue based on bladder acellular matrix-cell-three-dimensional fiber network and its preparation”; ZL201610395766.3
  6. [Zhang Yaopeng, Jiang Dan, Song Lujie, Shao Huili, Huang Jianwen, Fu Qiang, Hu Xuechao] (2019), “Biomimetic tissue based on acellular matrix-cell-three-dimensional fiber network and its preparation method ”; ZL201610395757.4
  7. [Zhang Yaopeng, Jiang Dan, Fu Qiang, Shao Huili, Song Lujie, Huang Jianwen, Hu Xuechao], (2019) "Composite acellular matrix hydrogel and preparation method thereof"; ZL201610395479.2
  • Shanghai Medical Science and Technology third Prize (first completed Adult, 2013) 
  • "Experimental Research and Clinical Application of Lower urinary tract Reconstruction using tissue Engineering";No.2012031401
  • Urethral repair and Reconstruction surgery. 
  • Shanghai Science and Technology Publishing House, 2022
  • Role: Associate Editor

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