SHENG Jiagen  

  • Chief Physician, Graduate Supervisor
  • Department: Orthopedics
  • Research Area: Surgery (Orthopedics)
  • Research Interests: Bone and soft tissue distraction techniques and treatment of femoral head necrosis
  • Contact: shengjiagen@126.com
  • PhD in Surgery from Shanghai Second Medical University, 2005
  • Master's Degree in Orthopedic Surgery from Shanghai Second Medical University, 1996
  • MD from Jinhua Health School, 1984
  • Executive Deputy Director of the 2nd Division of Repair and Reconstruction, Department of Orthopedics, Shanghai Sixth People's Hospital
  • Member of the Standing Committee of the Microsurgery Branch of the Chinese Medical Doctor Association and Chairman of the Professional Committee on Postoperative Rehabilitation of Microsurgery
  1. Zhu Z, Tang Q, Xu J, Gao Y, Chen Y, Yang K, et al. Treatment of Advanced Kienböck's Disease Using 3D Printing Assisted Autologous Costochondral Transplantation: A Case Report. JBJS Case Connect. 2022;12(4). Epub 2023/02/03. doi: e22.0064710.2106/jbjs.Cc.22.00647. PubMed PMID: 36732040.
  2. Lu Q, Xu Y, Li S, Zhang Z, Sheng J, Zhang Z. Clinical and biochemical characteristics of 12 Chinese primary hypertrophic osteoarthropathy patients with HPGD mutations. Int J Biol Sci. 2022;18(9):3908-17. Epub 2022/07/12. doi: 10.7150/ijbs.71261. PubMed PMID: 35813463; PubMed Central PMCID: PMCPMC9254467.
  3. Xu J, Zhan S, Ling M, Jiang D, Hu H, Sheng J, et al. Biomechanical analysis of fibular graft techniques for nontraumatic osteonecrosis of the femoral head: a finite element analysis. Journal of orthopaedic surgery and research. 2020;15(1):335. Epub 2020/08/19. doi: 10.1186/s13018-020-01867-4. PubMed PMID: 32807218; PubMed Central PMCID: PMCPMC7433362.
  4. Lu J, Guo SC, Wang QY, Sheng JG, Tao SC. J-bone graft with double locking plate: a symphony of mechanics and biology for atrophic distal femoral non-union with bone defect. Journal of orthopaedic surgery and research. 2020;15(1):144. Epub 2020/04/16. doi: 10.1186/s13018-020-01636-3. PubMed PMID: 32293488; PubMed Central PMCID: PMCPMC7161247.
  5. Lu J, Wang QY, Sheng JG. Exosomes in the Repair of Bone Defects: Next-Generation Therapeutic Tools for the Treatment of Nonunion. BioMed research international. 2019;2019:1983131. Epub 2019/08/31. doi: 10.1155/2019/1983131. PubMed PMID: 31467871; PubMed Central PMCID: PMCPMC6699293.
  6. Yin W, Xu H, Xu P, Hu T, An Z, Zhang C, et al. A Novel Guidewire Aiming Device to Improve the Accuracy of Guidewire Insertion in Femoral Neck Fracture Surgery Using Cannulated Screw Fixation. Medical science monitor : international medical journal of experimental and clinical research. 2016;22:2893-9. Epub 2016/08/17. doi: 10.12659/msm.897120. PubMed PMID: 27529374; PubMed Central PMCID: PMCPMC4996048.
  7. Xu H, Yin W, Hsu P, Qin H, An Z, Zhang C, et al. Improve the Efficiency of Surgery for Femoral Shaft Fractures with A Novel Instrument: A Randomized Controlled Trial. PLoS One. 2016;11(4):e0154332. Epub 2016/04/27. doi: 10.1371/journal.pone.0154332. PubMed PMID: 27115752; PubMed Central PMCID: PMCPMC4846024.
  8. Guo SC, Tao SC, Yin WJ, Qi X, Sheng JG, Zhang CQ. Exosomes from Human Synovial-Derived Mesenchymal Stem Cells Prevent Glucocorticoid-Induced Osteonecrosis of the Femoral Head in the Rat. Int J Biol Sci. 2016;12(10):1262-72. Epub 2016/10/22. doi: 10.7150/ijbs.16150. PubMed PMID: 27766040; PubMed Central PMCID: PMCPMC5069447.
  9. Gao YS, Zhang CQ, Sheng JG. Reverse Transfer of the Proximal Vascularized Fibula to Reconstruct the Lateral Malleolus: A Case Report and Literature Review. J Foot Ankle Surg. 2016;55(2):397-400. Epub 2015/05/23. doi: 10.1053/j.jfas.2015.02.004. PubMed PMID: 25998472.
  10. Gao YS, Liu XL, Sheng JG, Zhang CQ, Jin DX, Mei GH. Unilateral free vascularized fibula shared for the treatment of bilateral osteonecrosis of the femoral head. J Arthroplasty. 2013;28(3):531-6. Epub 2012/11/06. doi: 10.1016/j.arth.2012.09.002. PubMed PMID: 23122874.
  • 09/01/2022-08/31/2025
    Shanghai Municipal Health Commission Research Project, ¥8,000,000, 2022ZZ01014
    Clinical trials on the safety and efficacy of bone cement in filling and stabilizing vertebral bodies
    Role: Project leader
  • 10/01/2012-09/30/2015
    Shanghai Municipal Hospital Emerging Frontier Technology Joint Research Project, ¥500,000, SHDC12012115
    Reconstruction technique and functional evaluation of femoral head necrosis in adolescents
    Role: Project leader
  • 06/01/2014-06/01/2017
    Shanghai Municipal Health and Family Planning Commission Project, ¥13,270,000, 201402016
    Research on optimization, standardization and evaluation of key techniques for microsurgical repairing of severe limb tissue defects
    Role: Project leader
  1. [Jiagen Sheng, Zhenzhong Zhu, Changqing Zhang] (2021), “A heel pressure sensing insole and a heel pressure sensing sock sleeve”, CN 213045620 U
  2. [Jiagen Sheng, Meizhen Sheng, Changqing Zhang] (2022), “A fast extending rod device”, CN 215503323 U
  3. [Jiagen Sheng, Meizhen Sheng, Changqing Zhang] (2022), “An external fixator for orthopedics”, CN 216257348 U
  4. [Sanlian, Hu, Jiagen Sheng] (2022), “A load-bearable, adjustable, portable walking aid device”, CN 215504134 U
  5. [Sanlian, Hu, Jiagen Sheng, Yani Sun] (2023), “A bandage”, CN 218305311 U
  6. [Jiagen Sheng, Meizhen Sheng, Yun Gao, Changqing Zhang] (2024), “An anti-tipping skin stretcher”, CN 220385194 U

Translational Inventions: 

  • An Ilizarov external fixator (Invention patent), CN201410016167.7 
  • A bandage (Utility model patent), CN202122431486.2