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SHEN Longxiang  

  • Chief Physician, Doctoral Supervisor
  • Department: Orthopedics
  • Research Area: Biomedical Nanomaterials
  • Research Interests: Repair of Bone and Soft Tissue Defects
  • Contact: shenlongxiang@sjtu.edu.cn
Biography Positions Publications Research Projects Patents
  • Fellowship, Shanghai Jiao Tong University, 2010
  • PhD from Fudan University, 2009
  • MM from Zhejiang Chinese Medical University, 2003
  • Associate Group Leader, Orthopedics and Arthrology Professional Group of the Chinese Volunteer Association's Expert Volunteer Committee, Integrated Traditional Chinese and Western Medicine
  • Commissioner, Arthrology Group of the Orthopedics and Traumatology, Chinese Association for the Promotion of Traditional Chinese Medicine Research
  • Commissioner, Perthes Disease Group of the Pediatric Orthopedic Specialist Committee, Orthopedic Physicians Branch of the Chinese Medical Association
  • Expert, Construction of the Health Talent Evaluation Question Bank, National Health Commission Talent Exchange Service Center
  • Commissioner, Regeneration and Rehabilitation Committee, Chinese Rehabilitation Medicine Association
  • Youth Commissioner, Orthopedics and Traumatology Professional Committee, Shanghai Association of Traditional Chinese and Western Medicine
  • Editorial Board Member, Chinese Journal of Experimental Surgery
  • Youth Editorial Board Member, Chinese Bone Trauma
  • English Editor, International Journal of Orthopedics
  • Reviewer, Chinese Medical Journal
  1. Geng B, Hu J, Li Y, Feng S, Pan D#, Feng L#, Shen L#. Near-infrared phosphorescent carbon dots for sonodynamic precision tumor therapy. Nat Commun. 2022;13(1):5735. 
  2. Geng B#, Hu J, He X, Zhang Z, Cai J, Pan D#, Shen L#, Single Atom Catalysts Remodel Tumor Microenvironment for Augmented Sonodynamic Immunotherapy. Adv. Mater. 2024, 2313670.
  3. Tang J, Hu J, Bai X, Wang Y, Cai J, Zhang Z, Geng B#, Pan D#, Shen L#. Near-Infrared Carbon Dots With Antibacterial and Osteogenic Activities for Sonodynamic Therapy of Infected Bone Defects. Small. 2024 Dec;20(49):e2404900. 
  4. Hu J, Geng B, Glowacki J, Zhang S, Yang X, Pan D#, Shen L#. A biodegradable pn junction sonosensitizer for tumor microenvironment regulating sonodynamic tumor therapy. Chemical Engineering Journal. 2022 Oct 15;446:137320.
  5. Zhang S, Zhang L, Hu J, He X, Geng B#, Pan D#, Shen L#, Trienzyme-like Co3O4@TiO2-x nanozymes for heterojunction-enhanced nanocatalytic-sonodynamic tumor therapy. Chemical Engineering Journal. 2023;458:141485. 
  6. Geng B, Fang F, Li P, Xu S, Pan D#, Zhang Y#, Shen L#. Surface charge-dependent osteogenic behaviors of edge-functionalized graphene quantum dots. Chemical Engineering Journal. 2021;417:128125. 
  7. Hu J, He X, Cai J, Zhang Z, Bai X, Zhang S, Geng B#, Pan D#, Shen L#, Biodegradable CoSnO3 nanozymes modulate pH-responsive graphene quantum dot release for synergistic chemo-sonodynamic-nanocatalytic cancer therapy, Chemical Engineering Journal, 2024, 148561
  8. Geng B, Li P, Fang F, Shi W, Glowacki J, Pan D#, Shen L#. Antibacterial and osteogenic carbon quantum dots for regeneration of bone defects infected with multidrug-resistant bacteria. Carbon. 2021;184:375-85. 
  9. Geng B, Shen W, Fang F, Qin H, Li P, Wang X, Pan D#, Shen L#. Enriched graphitic N dopants of carbon dots as F cores mediate photothermal conversion in the NIR-II window with high efficiency. Carbon. 2020;162:14. 
  10. Geng B, Qin H, Shen W, Li P, Fang F, Li X, Pan D#, Shen L#. Carbon dot/WS2 heterojunctions for NIR-II enhanced photothermal therapy of osteosarcoma and bone regeneration. Chemical Engineering Journal. 2020;383:123102. 
  • 01/05/2024-31/04/2027
    Shanghai Jiaotong University,¥1000,000,20240816
    Peak discipline-clinical medicine 'research physician 'project, Shanghai Jiaotong University School of Medicine
    Role: Project leader
  • 01/01/2024-12/31/2027
    National Natural Science Foundation of China (General Program), ¥530,000, 12375345
    The effects and mechanism of a composite gel system modified by electron beam irradiation on tendon repair 
    Role: Project leader
  • 01/10/2023-09/30/2028
    Transverse Program, ¥2,500,000
    Integrated graphene quantum dots for promoting bone differentiation, broad-spectrum antibacterial, and fluorescent tracing in the repair of infectious bone and soft tissue defects 
    Role: Project leader
  • 01/04/2022-03/31/2025
    Shanghai Natural Science Foundation (General Program), ¥200,000, 22ZR1447600
    Research on the application of multifunctional integrated graphene quantum dots in bone repair engineering
    Role: Project leader
  • 01/01/2022-12/31/2025
    National Natural Science Foundation of China (General Program), ¥610,000, 12175142
    A novel antibacterial dressing modified by electron beam irradiation to promote wound healing 
    Role: Project leader
  • 10/01/2021-09/31/2024
    Shanghai Sixth People's Hospital Foundation (General Program), ¥300,000, YNMS202103
    A study on the repair of bone defects using amphiphilic graphene quantum dots based on promoting bone differentiation and antibacterial effects 
    Role: Project leader
  • 01/01/2013-12/31/2015
    National Natural Science Foundation of China (Youth Program), ¥230,000, 81201440
    Mechanism of WNT13 on the regulation of differentiation of bone marrow stromal cells in the type Ⅱ osteoporosis 
    Role: Project leader
  1. [Longxiang Shen, Qingcheng Yang, Bijiang Geng, et al](2024),"Preparation method and application of cobalt tetroxide supported titanium dioxide heterojunction nanozyme",Shanghai:CN115607670B
  2. [Longxiang Shen, Qingcheng Yang, Bijiang Geng, et al](2024),"Preparation method and application of Near-infrared phosphorescent carbon dots and cancer cell membrane encapsulated near-infrared fluorescent carbon dots composite nanoparticles",Shanghai:CN115245576B
  3. [Longxiang Shen, Qingcheng Yang, Bijiang Geng, et al] (2023), “A nitrogen doped carbon dot/lithium iron phosphate heterojunction, preparation method and application”, Shanghai: CN114177290B
  4. [Longxiang Shen, Bijiang Geng, Dengyu Pan] (2023), “A method for preparing graphene quantum dots”, Shanghai: CN110540192B
  5. [Longxiang Shen, Bijiang Geng, Dengyu Pan] (2023), “A graphene quantum dot/hydrogel composite, its preparation method and application”, Shanghai: CN111961227B
  6. [Longxiang Shen, Bijiang Geng, Dengyu Pan] (2023), “A metal ion coordinated carbon dot/titanium dioxide heterojunction and its preparation method and application”, Shanghai: CN113648414B
  7. [Longxiang Shen, Bijiang Geng, Dengyu Pan] (2022), “Preparation method of a carbon dot/titanium carbide heterojunction acoustic sensitizer and its application in sonodynamic cancer treatment”, Shanghai: CN112535731B
  8. [Longxiang Shen, Qinqing Wang, Wenyan Shi] (2022), “Preparation method of electron beam irradiation cross-linked calcium peroxide carbon quantum dots @ zein soluble protein antibacterial film”, Shanghai: CN112647193B
  9. [Longxiang Shen, Dengyu Pan, Bijiang Geng] (2022), “Preparation method and application of near-infrared responsive carbon dots”, Shanghai: CN110066654B
  10. [Longxiang Shen, Bijiang Geng, Dengyu Pan] (2022), “Carbon quantum dot hydrogel composite scaffold material, preparation method and application”, Shanghai: CN113398334B
  11. [Longxiang Shen, Jiezhi Dai, Yunzhong Shi] (2022), “A hip joint treatment plaster fixation device”, Shanghai: CN216603218U
  12. [Longxiang Shen, Yilan Zhou, Wenshuai Ji, et al] (2022), “A Kirschner wire internal fixation guide device for children with supracondylar fractures of the humerus”, Shanghai: CN216060712U
  13. [Longxiang Shen, Qingcheng Yang, Bijiang Geng, et al] (2022), “A nitrogen doped carbon dot/lithium iron phosphate heterojunction, preparation method and application”, Shanghai: CN114177290A
  14. [Longxiang Shen, Jianfei Tang, Wenshuai Ji, et al] (2022), “A surgical knee joint restraint device”, Shanghai: CN215937872U
  15. [Longxiang Shen, Zhiquan An, Congfeng Luo] (2022), “An anatomical locking plate for vertically unstable pubic symphysis separation”, Shanghai: CN215503331U
  16. [Longxiang Shen, Dengyu Pan] (2021), “Preparation method and application of a yellow fluorescent biological imaging material”, Shanghai: CN110272359B
  17. [Longxiang Shen, Jing Chen, Dongsheng Cheng, et al] (2021), “A suction device and electric knife integrated surgical device”, Shanghai: CN215079565U
  18. [Longxiang Shen, Wenshuai Ji, Jianfei Tang, et al] (2021), “A surgical fracture reduction forceps”, Shanghai: CN214857360U
  19. [Longxiang Shen, Jianwei Wang, Yamin Li, et al] (2021), “An anatomical locking plate for the foot navicular bone”, Shanghai: CN214857347U
  20. [Longxiang Shen, Bijiang Geng, Dengyu Pan] (2021), “A metal ion coordinated carbon dot/titanium dioxide heterojunction and its preparation method and application”, Shanghai: CN113648414A
  21. [Longxiang Shen, Bijiang Geng, Dengyu Pan] (2021), “Carbon quantum dot water gel composite scaffold materials, preparation methods and applications”, Shanghai: CN113398334A
  22. [Longxiang Shen, Wenshuai Ji, Xing Yan, et al] (2021), “A surgical scapular area inflation device”, Shanghai: CN213346616U
  23. [Longxiang Shen, Qinqing Wang, Wenyan Shi] (2021), “Preparation method of electron beam irradiation cross-linked calcium peroxide carbon quantum dots @ zein soluble protein antibacterial film”, Shanghai: CN112647193A
  24. [Longxiang Shen, Bijiang Geng, Dengyu Pan] (2021), “Preparation method of a carbon dot/titanium carbide heterojunction acoustic sensitizer and its application in sonodynamic cancer treatment”, Shanghai: CN112535731A
  25. [Longxiang Shen, Bijiang Geng, Dengyu Pan] (2021), “A graphene quantum dot/hydrogel composite, its preparation method and application”, Shanghai: CN111961227A
  26. [Longxiang Shen, Bijiang Geng, Dengyu Pan] (2019), “A method for preparing graphene quantum dots”, Shanghai: CN110540192A
  27. [Longxiang Shen, Dengyu Pan] (2019), “Preparation method and application of a yellow fluorescent biological imaging material”, Shanghai: CN110272359A
  28. [Longxiang Shen, Dengyu Pan, Bijiang Geng] (2019), “Preparation method and application of near-infrared responsive carbon dots”, Shanghai: CN110066654A

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