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PENG Xiaochun  

  • Chief Physician, Graduate Supervisor, Associate Professor
  • Department: Orthopedics
  • Research Area: Surgery (Orthopedics)
  • Research Interests: Aseptic loosening, Osteoarthritis
  • Contact: dr.xcpeng@foxmail.com
Biography Positions Publications Research Projects Patents
  • Chief physician, Shanghai Sixth People's Hospital, Orthopedics, 2022
  • Associate chief physician, Shanghai Sixth People's Hospital, Orthopedics, 2017
  • Attending doctor, Shanghai Sixth People's Hospital, Orthopedics, 2012
  • Resident doctor, Shanghai Sixth People's Hospital, Orthopedics, 2009
  • PhD from Shanghai Jiao Tong University, 2009
  • Chief physician, Department of Orthopedics, Shanghai Sixth People's Hospital
  1. Lei Y, Guo X, Luo Y, Niu X, Xi Y, Xiao L, He D, Bian Y, Zhang Y, Wang L, Peng X*, Wang Z*, Chen G*. Synovial microenvironment-influenced mast cells promote the progression of rheumatoid arthritis. Nat Commun, 2024,doi:10.1038/s41467-023-44304-w.
  2. Wu R, Pang S, Lv W, Zou J, Li Y, Li Y, He J, Gu H , Wang Y , Guan Y, Peng X*, Wang Y*, Liu S*. Injectable pH-responsive CI1040 delayed-release hydrogel for the treatment of tendon adhesion. Adv Funct Mater, 2024, doi:10.1002/adfm.202314731.
  3. He J, Zhou S, Wang J, Sun B, Ni D*, Wu J*, Peng X*; Anti-inflammatory and anti-oxidative electrospun nanofiber membrane promotes diabetic wound healing via macrophage modulation. J Nanobiotechnology, 2024,doi: 10.1186/s12951-024-02385-9.
  4. Zhu W, Liu Q, Zhang Z, Wang Y, Mei J, Xu D, Zhou J, Su Z, Zhang X, Zhu C, Wang J*, Zhu J*, Peng X*, Zhang X*. Photothermal Microneedle Hydrogel Patch for Refractory Soft Tissue Injuries through Thermosensitized Anti-Inflammaging Modulation. Small Struct, 2024,doi: 10.1002/sstr.202400014.
  5. Lei K, Wang Y, Peng X*, Yu L*, Ding J. Long-term delivery of etanercept mediated via a thermosensitive hydrogel for efficient inhibition of wear debris-induced inflammatory osteolysis. J Polym Science, 2022,doi: 10.1002/pol.20220337.
  6. Zhou L, Pan M, Zhang Z, Diao Z, Peng X*. Enhancing osseointegration of TC4 alloy by surficial activation through biomineralization method. Front Bioeng Biotechnol, 2021,doi: 10.3389/fbioe.2021.639835.
  7. Wang F, Ma L, Ding Y, He L, Chang M, Shan Y, Siwko S, Chen G, Liu Y, Jin Y*,Peng X*, Luo J*. Fatty acid sensing GPCR (GPR84) signaling safeguards cartilage homeostasis and protects against osteoarthritis. Pharmacol Res, 2020,doi: 10.1016/j.phrs.2020.105406.
  8. Lei K, Chen Y, Wang J, Peng X*, Yu L*, Ding J. Non-invasive monitoring of in vivo degradation of a radiopaque thermoreversible hydrogel and its efficacy in preventing post-operative adhesions. Acta Biomater, 2017,doi: 10.1016/j.actbio.2017.03.042.
  9. Peng X, Chen Y, Li Y, Wang Y, Zhang X. A long-acting BMP-2 release system based on Poly(3-hydroxybutyrate) nanoparticles loading BMP-2 modified by amphiphilic phospholipid for osteogenic differentiation. Biomed Res Int, 2016,doi: 10.1155/2016/5878645.
  10. Peng X, Zhang X, Cheng T, Cheng M, Wang J. Comparison of the quadriceps-sparing and subvastus approaches versus the standard parapatellar approach in total knee arthroplasty: a meta-analysis of randomized controlled trials. BMC Musculoskelet Disord, 2015,doi: 10.1186/s12891-015-0783-z.
  11. Peng X, Cheng T, Cheng M, Wang J, Zhang X. Hierarchically Porous CaCO3 Monoliths Prepared From Leaf Template. Mater Lett, 2014,doi: 10.1016/j.matlet.2014.05.027.
  12. Peng X, Chen J, Cheng T, Zhao S, Ji J, Hu H, Zhang X. PLGA modified Fe3O4 nanoclusters for siRNA delivery. Mater Lett, 2012,doi:  10.1016/j.matlet.2012.04.127.
  13. Peng X, Tao K, Cheng T, Zhu J, Zhang X. Efficient Inhibition of wear debris-induced inflammation by locally delivered siRNA. Biochem Biophys Res Commun, 2008,doi: 10.1016/j.bbrc.2008.10.026.
  14. Peng X, Zhang X, Zeng B. Locally administered lentivirus-mediated siRNA inhibits wear debris-induced inflammation in murine air pouch model. Biotechnol Lett, 2008,doi: 10.1007/s10529-008-9788-0.
  • 01/01/2020-12/31/2023
    National Natural Science Foundation of China (Key Program), ¥550,000, 81974326
    Study on the effect and mechanism of PEG/polyester thermogel sustained release of miRNA-exosome targeting TNF-α to prevent joint prosthesis loosening
    Role: Project leader
  1. [Zhang Xianlong, Peng Xiaochun, Cheng Tao, Shi Sifeng, Guo Yongyuan] (2011), “Preparation and application of magnetic nanoclusters modified by PLGA”, ZL 201110446700.X 
  2. [Peng Xiaochun, Zhang Xianlong, Chen Yunsu, Yu Xiaowei] (2015), “A proximal hip fixation prosthesis”, ZL 201520004498.9
  3. [Peng Xiaochun, Zhang Xianlong, Chen Yunsu, Yu Xiaowei] (2015), “Prosthesis (proximal coating)”, ZL 201530004127.6 
  4. [Peng Xiaochun, Zhang Xianlong, Chen Yunsu, Yu Xiaowei] (2015), “Prosthesis (distal coating)”, ZL 201530004265.4

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