MIN Daliu  

  • Doctoral Supervisor, Professor
  • Department: Oncology
  • Research Area: Oncology
  • Research Interests: Mechanism of drug resistance of osteosarcoma
  • Contact: mindaliu1969@163.com
  • Fellowship, Department of Oncology, Shanghai Sixth People's Hospital, 2010
  • MD/PhD from Fudan University Shanghai Cancer Center, 2004
  • MPH from Anhui Medical University, 1998
  • Vice Director, Department of Oncology, Shanghai Sixth People's Hospital
  1. Zhouliang Bian, Benhong Gu, Guohai Shi, Jiahui Guo, Dong, Hanlin Zeng, Bin Jiang, Daliu Min#, Hengchuan Su ,Yanjie Zhang#. Single-cell landscape reveals unique tumor subsets and microenvironment associated with poor clinical outcomes in primary testicular diffuse large B-cell lymphoma. Genes & Diseases 2024;11:80-83 
  2. Zhihan Jiang, Kun Han, Daliu Min#, Wei Kong, Shuaiqun Wang and Min Gao. Identification of the methotrexate resistance-related diagnostic markers in osteosarcoma via adaptive total variation netNMF and multi-omics datasets. Front. Genet. 14:1288073. doi: 10.3389/fgene.2023.1288073 
  3. Zhou M, Zhou S, Han K, Zhang J, Chen Q, Tian C, Zhu H, Jiang M, Min D#. Th1 immune maturation effects of Nocardia rubra cell-wall skeleton via PI3K/Akt/PAX8 regulatory axis. Sci Prog. 2022;105(2):368504221092901.
  4. Yujing Huang, Aina He, Lina Tang, Xue Cheng, Zan Shen, Yang Yao, Daliu Min#. The timing of targeted therapy initiation in metastatic sarcoma as an adjuvant to first-line chemotherapy or a second-line agent. Am J Transl Res 2021;13(8):9095-9103
  5. Yujing Huang, Zan Shen, Yang Yao, Aina He, Daliu Min#. The Plasma Concentration of D-Dimer is Associated with Neoadjuvant-Chemotherapy Efficacy and the Prognosis in Osteosarcoma. OncoTargets and Therapy 2021:14 213–220 
  6. Cong Tian, Tingyuan Lang, Jiangfeng Qiu, Kun Han, Lei Zhou, Daliu Min, Zhiqi Zhang,Dachuan Qi. SKP1 promotes YAP-mediated colorectal cancer stemness via suppressing RASSF1. Cancer Cell Int (2020) 20:579 
  7. Xingxing Sun, Cong Tian, Hui Zhang, Kun Han, Meixiang Zhou, Zhihua Gan, Hongling Zhu, Daliu Min#. Long noncoding RNA OIP5-AS1 mediates resistance to doxorubicin by regulating miR-137-3p/PTN axis in osteosarcoma. Biomedicine & Pharmacotherapy; 28 (2020) 110201   
  8. Wenxi Yu, Daliu Min#, Feng Lin,Shuier Zheng, Lina Tang, Aina He, Haiyan Hu and Zan Shen. SKA1 induces de novo MTX-resistance in osteosarcoma through inhibiting FPGS transcription. FEBS J 2019;286 (12), 2399-2414
  9. Han K, Lang T,Zhang Z, Zhang Y, Sun Y, Shen Z, Beuerman RW, Zhou L#, Min D#. Luteolin attenuates Wnt signaling via upregulation of FZD6 to suppress prostate cancer stemness revealed by comparative proteomics. Sci Rep;2018;4;8(1):8537. 
  10. Yan Zhou, Shuchen Lin, Kuo-Fu Tseng, Kun Han, Yaling Wang, Zhihua Gan, Daliu Min#, Hai-yan Hu. Selumetinib suppresses cell proliferation, migration and trigger apoptosis, G1 arrest in triple-negative breast cancer cells. BMC Cancer. 2016;16(1):818. 
  • 07/01/2021-06/30/2024
    Natural Science Foundation of Science and Technology Commission of Shanghai Municipality,¥200,000,21ZR1449000
    The Mechanism Study of Abnormal m6a Modification Activating NF-κB Signaling Pathway to Promote drug resistance and Vascular Abnormalities in Refractory Osteosarcoma
    Role: Project leader
  • 07/01/2021-06/30/2024
    Natural Science Foundation of Science and Technology Commission of Shanghai Municipality,¥200,000,19ZR1439100
    Mechanism study of miR-34b from osteosarcoma-derived exosomes reverses   multi-drug resistance of osteosarcoma cells via inhibiting M2 phenotype macrophage polarization
    Role: Project leader
  • 01/01/2019-12/31/2021
    Clinical Trial Foundation of Shanghai Municipal Health Commission,¥100,000,201840039
    Mechanism study of sirolimus reverse the multidrug resistance of osteosarcoma cells by PAK1 signaling pathway
    Role: Project leader
  • 01/01/2015-12/31/2017
    Natural Science Foundation of Science and Technology Commission of Shanghai Municipality,¥200,000,15ZR1432400
    The molecular mechanism of MPP8 mediated autophagy associated with multidrug resistance in human osteosarcoma
    Role: Principal Investigator
  • 01/01/2012-12/31/2015
    National Natural Science Foundation of China, ¥550,000, 81172548
    Study on the molecular mechanism of protein kinase PAK5 associated with drug resistance in osteosarcoma
    Role: Project leader