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LIU Zhiyan
- Chief Physician, Doctoral Supervisor, Associate Professor
- Department: Pathology
- Research Area: Pathology
- Research Interests: Endocrine pathology and bone and soft tissue tumor
- Contact: zhiyanliu@shsmu.edu.cn
- Visiting Scholar, University of Michigan, USA, 2018
- MD, Ph.D from Wakayama Medical University, Japan, 2011
- MD, Ph.D from Shandong University, China, 2011
- Master's degree from Huazhong University of Science and Technology, China, 2002
- Bachelor's degree from Jining Medical University, China, 1999
- Director, Department of Pathology, Shanghai Sixth People's Hospital
- Vice President, Thyroid Cancer Committee of Chinese Society of Clinical Oncology
- Committee Member, Tumor Pathology Committee of Chinese Cancer Anti-Cancer Association
- Member, Asian Thyroid Working Group
- Member, the International Academy of Cytology and American Thyroid Association
- Wang Q,Wang Y, Chen C, Zhang L,Wang C,Lou X, Chen ,Jin J,Fan Y,Sui S,Liu Z.Study on association between human plasma polybrominated diphenyl ethers (PBDEs) and thyroid homeostasis and carcinoma. Environmental geochemistry and health .2024 Nov, 46, (12), 502.
- Wang X,Cui X,Wang Y, Wang Q,Sun F,Liu Z.Decabromodiphenyl ether exposure reduces dabrafenib sensitivity of papillary thyroid carcinoma harboring BRAF(V600E) mutation through the EGFR-CRAF-MAPK pathway: An in vitro study. Toxicology.2024 May, 504, 153807.
- Zhou J, Su X, Hu D, Zhang L, Chen C, Sun K, Zhang H, Liu Z. Molecular confirmation that fibrocartilaginous dysplasia is a variant of fibrous dysplasia. J Clin Pathol. 2024 Aug 17:jcp-2024-209626
- Zhao Q, Tang J, Luo Y, Huang J, Hu D, Zhu J, Jiang T, Zhang H, Liu Z. Chondroblastoma: clinicopathological analyses of 307 cases from a single institution in China and the diagnostic value of the H3F3 K36M mutant antibody. J Clin Pathol. 2023 Jun;76(6):367-373
- Yanli Luo, Juan Tang, Jin Huang, Dingjun Hu, Yueqing Bai, Jie Chen, Keyang Sun, Huizhen Zhang, Zhiyan Liu. Diagnostic value of H3F3A mutation and clinicopathological features of giant cell tumours in non-long bones. Journal of Bone Oncology, 38,2023,100467
- Wang, X.; Cui, X.; Zhao, Q.; Sun, F.; Zhao, R.; Feng, T.; Sui, S.; Han, B.; Liu, Z. Long term Exposure to Decabromodiphenyl Ether Promotes the Proliferation and Tumourigenesis of Papillary Thyroid Carcinoma by Inhibiting TRß. Cancers 2022, 14(11), 2772
- Sui S, Gao Y, Yuan T, He C, Peng C, Wang Y, Liu Z. Pollution characteristics and health risk assessment of PM2.5-bound arsenic: a 7-year observation in the urban area of Jinan, China. Environ Geochem Health. 2022 Dec;44(12):4619-4630
- Sui S, Ng J, Gao Y, Peng C, He C, Wang G, Liu Z. Pollution characteristics and chronic health risk assessment of metals and metalloids in ambient PM2.5 in Licheng District, Jinan, China. Environ Geochem Health. 2020 Jul;42(7):1803-1815
- Liu Z., Andrey Bychkov, Chan Kwon Jung, Mitsuyoshi Hirokawa, Shaofeng Sui, SoonWon Hong, Chiung-Ru Lai, Deepali Jain, Sule Canberk, Kennichi Kakudo. Interobserver and intraobserver variation in the morphological evaluation of noninvasive follicular thyroid neoplasm with papillary like nuclear features in Asian practice. Pathol Intl, 2019. Apr;69(4):202-210
- Liu Z, Zhou G, Nakamura M, Koike E, Li Y, Ozaki T, Mori I, Taniguchi E, Kakudo K. Encapsulated follicular thyroid tumor with equivocal nuclear changes, so-called well-differentiated tumor of uncertain malignant potential, a morphological, immunohistochemical, and molecular appraisal. Cancer Sci. 2011, 102(1):288-94.10.
- 01/01/2025-31/12/2028
National Natural Science Foundation of China, ¥490,000, 82472629
The effect and mechanism of long-term exposure of perfluorooctane sulfonates(PFOS) inducing thyroid carcinoma by activing PPARG.
Role: Project leader - 01/04/2023-31/03/2026
Science and Technology Innovation Plan of Science and Technology Commission of Shanghai Municipality (STCSM) , ¥200,000, 23ZR1448200
The effect and mechanism of long-term exposure of perfluorooctanoic acid (PFOA) inducing carcnoigenesis of thyroid carcinoma through peroxisome proliferators-activated receptor γ
Role: Project leader - 01/12/2020-30/11/2024
Science and Technology Innovation Plan of Science and Technology Commission of Shanghai Municipality (STCSM) , ¥400,000, 20Z11900304
Tracing model of primary unknown tumor in bone metastatic tumor
Role: Project leader - 01/08/2020-30/07/2023
Shanghai Sixth People's Hospital high-level talent introduction research start-up fund, ¥300,000, （20200701）
The mechanism of thyroid cancer induced by long-term exposure of decabromodi-phenyl ether (BDE-209) in indoor air
Role: Project leader - 01/01/2020-31/12/2023
National Natural Science Foundation of China, ¥550,000, 81972500
The mechanism of long-term exposure of decabromodi-phenyl ether (BDE-209) inducing tumorigenesis of papillary thyroid carcinoma through thyroid hormone receptor signal way
Role: Project leader - 01/07/2019-01/06/2022
Shandong Province nature fund surface project, ¥200,000, ZR2019MH024
The mechanism of excessive exposure of decabromodi-phenyl ether (BDE-209) inducing thyroid carcinoma
Role:Project leader
- 01/04/2023-31/03/2026
Science and Technology Innovation Plan of Science and Technology Commission of Shanghai Municipality (STCSM) , ¥200,000, 23ZR1448200
The effect and mechanism of long-term exposure of perfluorooctanoic acid (PFOA) inducing carcnoigenesis of thyroid carcinoma through peroxisome proliferators-activated receptor γ
Role: Subject leader - 01/12/2020-30/11/2024
Science and Technology Innovation Plan of Science and Technology Commission of Shanghai Municipality (STCSM) , ¥400,000, 20Z11900304
Tracing model of primary unknown tumor in bone metastatic tumor
Role: Subject leader - 01/08/2020-30/07/2023
Shanghai Sixth People's Hospital high-level talent introduction research start-up fund, ¥300,000, （20200701）
The mechanism of thyroid cancer induced by long-term exposure of decabromodi-phenyl ether (BDE-209) in indoor air
Role: Subject leader - 01/01/2020-31/12/2023
National Natural Science Foundation of China, ¥550,000, 81972500
The mechanism of long-term exposure of decabromodi-phenyl ether (BDE-209) inducing papillary thyroid carcinoma through thyroid hormone receptor β
Role: Subject leader - 00/07/2019-00/06/2022
Shandong Province nature fund surface project, ¥200,000, ZR2019MH024
The mechanism oflong-term exposure of decabromodi-phenyl ether (BDE-209) inducing thyroid carcinoma
Role: Subject leader
