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LIU Xudong  

  • Chief Physician, Doctoral Supervisor, Professor
  • Department: Orthopedics
  • Research Area: Surgery (Orthopedics)
  • Research Interests: AI; Tissue engineering
  • Contact: doctorliuxd@126.com
Biography Positions Publications Research Projects
  • Fellowship, Massachusetts General Hospital, Harvard University, Department of Orthopaedic Surgery, 2012-2013
  • PhD from Shanghai Jiao Tong University, 2006
  • M.Sc from Jilin University, 2003
  • MD from Norman Bethune University of Medicine Science, 2000
  • Chief Physician, Division of Sports Medicine, Department of Orthopedics, Shanghai Sixth People's Hospital
  1. Ying M, Wang Y, Yang K, Wang H, Liu X. A deep learning knowledge distillation framework using knee MRI and arthroscopy data for meniscus tear detection. Front Bioeng Biotechnol. 2024 Jan 15;11:1326706. doi: 10.3389/fbioe.2023.1326706.
  2. Qu C, Yang H, Wang C, Wang C, Ying M, Chen Z, Yang K, Zhang J, Li K, Dimitriou D, Tsai TY, Liu X. A deep learning approach for anterior cruciate ligament rupture localization on knee MR images. Front Bioeng Biotechnol. 2022 Sep 30;10:1024527. doi: 10.3389/fbioe.2022.1024527. 
  3. Cai Z, Zhang Y, Liu S, Liu X. Celecoxib, Beyond Anti-inflammation, Alleviates Tendon-Derived Stem Cell Senescence in Degenerative Rotator Cuff Tendinopathy. Am J Sports Med. 2022 Jul;50(9):2488-2496. doi: 10.1177/03635465221098133. Epub 2022 Jun 6.
  4. Cai Z, Li Y, Song W, He Y, Li H, Liu X. Anti-Inflammatory and Prochondrogenic In Situ-Formed Injectable Hydrogel Crosslinked by Strontium-Doped Bioglass for Cartilage Regeneration. ACS Appl Mater Interfaces. 2021 Dec 22;13(50):59772-59786. doi: 10.1021/acsami.1c20565. Epub 2021 Dec 13.
  5. Yao Z, Xue T, Xiong H, Cai C, Liu X, Wu F, Liu S, Fan C. Promotion of collagen deposition during skin healing through Smad3/mTOR pathway by parathyroid hormone-loaded microneedle. Mater Sci Eng C Mater Biol Appl. 2021 Feb;119:111446. doi: 10.1016/j.msec.2020.111446. Epub 2020 Aug 27.
  6. Xie S, Li K, Wang C, Liu X, Zhao L, Tsai TY. Multi-View Point-Based Registration for Native Knee Kinematics Measurement with Feature Transfer Learning. Engineering. 2021 Jun 1;7(6):881–8.
  7. Zhang X, Cai Z, Wu M, Huangfu X, Li J, Liu X. Adipose Stem Cell-Derived Exosomes Recover Impaired Matrix Metabolism of Torn Human Rotator Cuff Tendons by Maintaining Tissue Homeostasis. Am J Sports Med. 2021 Mar;49(4):899-908. doi: 10.1177/0363546521992469.
  8. Wang C, Wu T, Liu G, Cheng R, Fei J, Song X, Chai Y, Fan C, Liu X, Cui W, Liu S. Promoting coagulation and activating SMAD3 phosphorylation in wound healing via a dual-release thrombin-hydrogel. Chemical Engineering Journal. 2020 Oct 1;397:125414.
  9. Wang C, Song W, Chen B, Liu X, He Y. Exosomes Isolated From Adipose-Derived Stem Cells: A New Cell-Free Approach to Prevent the Muscle Degeneration Associated With Torn Rotator Cuffs. Am J Sports Med. 2019 Nov;47(13):3247-3255. doi: 10.1177/0363546519876323. Epub 2019 Sep 27. 
  10. Wang C, Chen B, Wang W, Zhang X, Hu T, He Y, Lin K, Liu X. Strontium released bi-lineage scaffolds with immunomodulatory properties induce a pro-regenerative environment for osteochondral regeneration. Mater Sci Eng C Mater Biol Appl. 2019 Oct;103:109833. doi: 10.1016/j.msec.2019.109833. Epub 2019 May 30.
  11. Wang C, Hou W, Guo X, Li J, Hu T, Qiu M, Liu S, Mo X, Liu X. Two-phase electrospinning to incorporate growth factors loaded chitosan nanoparticles into electrospun fibrous scaffolds for bioactivity retention and cartilage regeneration. Mater Sci Eng C Mater Biol Appl. 2017 Oct 1;79:507-515. doi: 10.1016/j.msec.2017.05.075. Epub 2017 May 14.
  12. Wang C, Liu G, Zhang W, Wang W, Ma C, Liu S, Fan C, Liu X. Cartilage oligomeric matrix protein improves in vivo cartilage regeneration and compression modulus by enhancing matrix assembly and synthesis. Colloids Surf B Biointerfaces. 2017 Nov 1;159:518-526. doi: 10.1016/j.colsurfb.2017.08.008. Epub 2017 Aug 16.
  13. Liu X, Li JS, Hosseini A, Gill TJ, Li G. Anteromedial and posterolateral graft kinematics of a double-bundle ACL reconstruction: a 3D computer simulation. Int J Med Robot. 2016 Mar;12(1):96-101. doi: 10.1002/rcs.1645. Epub 2015 Jan 27.
  14. Liu X, Huangfu X, Zhao J. Arthroscopic treatment of acute acromioclavicular joint dislocation by coracoclavicular ligament augmentation. Knee Surg Sports Traumatol Arthrosc. 2015 May;23(5):1460-1466. doi: 10.1007/s00167-013-2800-9. Epub 2013 Dec 10.
  15. Liu S, Wu J, Liu X, Chen D, Bowlin GL, Cao L, Lu J, Li F, Mo X, Fan C. Osteochondral regeneration using an oriented nanofiber yarn-collagen type I/hyaluronate hybrid/TCP biphasic scaffold. J Biomed Mater Res A. 2015 Feb;103(2):581-92. doi: 10.1002/jbm.a.35206. Epub 2014 May 7.
  16. Liu X, Liu S, Liu S, Cui W. Evaluation of oriented electrospun fibers for periosteal flap regeneration in biomimetic triphasic osteochondral implant. J Biomed Mater Res B Appl Biomater. 2014 Oct;102(7):1407-14. doi: 10.1002/jbm.b.33119. Epub 2014 Feb 20.
  17. Liu X, Gao L, Zhao A, Zhang R, Ji B, Wang L, Zheng Y, Zeng B, Valenzuela RK, He L, Ma J. Identification of duplication downstream of BMP2 in a Chinese family with brachydactyly type A2 (BDA2). PLoS One. 2014 Apr 7;9(4):e94201. doi: 10.1371/journal.pone.0094201.
     
  • 01/01/2022-12/31/2025
    National Natural Science Foundation of China (General Program), ¥550,000, 62176157
    Knee joint disease diagnosis based on cross-modal deep learning
    Role: Project leader
  • 01/01/2023-12/31/2025
    Shanghai Jiao Tong University School of Medicine, ¥1,000,000, SBR2022003
    Study on diagnosis and treatment decision model of anterior cruciate ligament injury based on deep learning
    Role: Project leader
  • 01/01/2019-12/31/2022
    National Natural Science Foundation of China (General Program), ¥570,000, 81873997
    Study of strontium-containing bioactive glass linked in suit-forming hydrogels on promoting cartilage repairment by modulating M2 macrophages polarization and exosomes secretion
    Role: Project leader

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