Research Area:
Basic and clinical research of bone and joint diseases
Research Interests:
Cartilage injury and repair, diagnosis and treatment of femoral head osteonecrosis, application of digital orthopedic technology in joint surgery
2011-09 to 2014-07, Department of Orthopedics, Shandong University, Ph.D
2009-06 to 2010-07, Department of Orthopedics, Massachusetts General Hospital, Harvard University, Fellowship
1997-07 to 2000-07, Qingdao University, Master degree in Orthopaedics
1988-09 to 1993-07, Harbin Medical University, Clinical Medicine, Bachelor degree
Temporary Head of Joint Surgery, Department of Orthopedics, Shanghai Sixth People's Hospital (Lingang Campus)
Jiang Z, Lü X, Zheng N, et al. Iso-height axis correlates with collateral ligament balance in medial compartment knee osteoarthritis. Front Bioeng Biotechnol. 2025;13:1695631.
Jiang Z, He A, Liu Y, et al. Chiral Hydroxyapatite Coatings for Improving Bone In-Growth of Porous Tantalum Scaffold via FAK-Notch1 Signaling Pathway. Adv Healthc Mater. 2025;14(32):e02140.
Li L, He A, Zhao H, et al. Rational design and structure-activity relationship of random copolymers for enhanced siRNA delivery. J Colloid Interface Sci. 2025;690:137273.
Liu Y, Zhou C, Zhang X, Liu W. Chirality Hydroxyapatite Gradient Scaffold Drives Osteochondral Regeneration via YAP/TAZ-Mediated Mechanotransduction. Adv Healthc Mater. 2025;14(22):e2501668.
Zhang R, Liu Y, Zang H, He A, Mao Y, Liu W. Role and mechanism of lncRNA ZEB1-AS1 endogenous competition for miR-365a-3p targeting NRF2 in ferroptosis in articular chondrocytes. J Mol Histol. 2025;56(3):190.
Zang H, Wang L, Wu Y, Chang J, Liu W. Integrated bioinformatics and network pharmacology to identify and validate macrophage polarization related hub genes in the treatment of osteoarthritis with Astragalus membranaceus. J Orthop Surg Res. 2025;20(1):543.
Jiang Z, He A, Zheng N, et al. Medial Compartment Knee Osteoarthritis Altered Tibiofemoral Joint Kinematics and Contact Pattern During Daily Weight-Bearing Extension. Orthop Surg. 2025;17(5):1478-1485.
Jiang Z, Zhen N, Mao Y, et al. HKA angle exceeding 5 degrees is strongly associated with lateral patellar translation beyond 2 mm: surgical recommendations for avoiding adverse effects on the patellofemoral joint after OWHTO. J Orthop Surg Res. 2025;20(1):45.
Jiang Z, Zheng N, He A, et al. Digging into the Cause of Abnormal Patellar Kinematics After Open-Wedge High Tibial Osteotomy via a Quantitative Study on In Vivo Soft Tissue Functional Changes. Bioengineering (Basel). 2025;12(2):123.
He A, Liu Y, Zhang R, Mao Y, Liu W. CircSFMBT2-OA alleviates chondrocyte apoptosis and extracellular matrix degradation through repressing NF-κB/NLRP3 inflammasome activation. Heliyon. 2023;9(6):e17312.
Shanghai Pudong New Area Health Commission, Joint research project, PW2023D-09, Establishment and promotion of technical standards for high tibial osteotomy combined with tibial tuberosity osteotomy in the treatment of osteoarthritis, 2023-12 to 2026-11, CNY 300 000, in progress, Principal Investigator
Shanghai Science and Technology Commission, General Project of Natural Science Foundation of Shanghai 2021 Science and Technology Innovation Action Plan,21ZR1448900, The role and mechanism of DLK2 mediating the interaction between Notch and p38MAPK pathway in the repair of articular cartilage defects by bone marrow mesenchymal stem cells (BMSCs) tissue engineering,2021-07 to 2024-06, CNY 200 000, in research, PI
Shanghai Municipal Health and Wellness Commission, Healthy Aging Project of Shanghai Municipal Health Commission, 2020YJZX0120, The role and mechanism of DLK2 in the repair of articular cartilage defects by tissue engineering, 2020-09 to 2023-08, CNY 300 000, In research, PI
Liu Wanjun; He A Xiang; Zhang Xian-long; Ouyang Yuanming; Wang Wei; Zhang Hui; Zhou Ying; Chen Dan-qing; A forceps for removing free bone fragment after osteotomy in total joint arthroplasty, 2020-12-11, China, ZL202020287104.6
Liu Wanjun; He A Xiang; Zhang Xian-long; Ouyang Yuanming; Wang Wei; Zhang Hui; Zhou Ying; Chen Dan-qing; A kind of free bone block traction forceps for bone platform, 2020-12-11, China, ZL202020288034.6