Research
Search
Close
LIN Yi
- Doctoral Supervisor, Professor
- Department: Gynaecology and Obstetrics
- Research Area: Gynaecology and Obstetrics
- Research Interests: Pathogenesis of pregnancy-related diseases
- Contact: yilinonline@sjtu.edu.cn
- Post-Doc at Zhongshan Medical School, Zhongshan University, 2002-2004
- MD from Jinan University, Guangzhou, 2002
- Master’s Degree from the Fourth Military Medical University, 1995
- Bachelor’s Degree from the Fourth Military Medical University, 1989
- Professor, Department of Gynaecology and Obstetrics, Shanghai Sixth People’s Hospital
- Wu J, Qin C, Tian F, Liu X, Hu J, Wu F, Chen C, Lin Y*. Epigenetic drug screening for trophoblast syncytialization reveals a novel role for MLL1 in regulating fetoplacental growth. BMC Medicine 2024,22:57. https://doi.org/10.1186/s12916-024-03264-8
- Xu Y, Wu F, Qin C, Lin Y. Paradoxical role of phosphorylated STAT3 in normal fertility and the pathogenesis of adenomyosis and endometriosis. Biology of Reproduction 2024,110(1):5-13.
- Xu Y, Liu X, Zeng W, Zhu Y, Dong J, Wu F, Chen C, Sharma S, Lin Y*. DOCK1 insufficiency disrupts trophoblast function and pregnancy outcomes via DUSP4-ERK pathway. Life Science Alliance 2023, 7(2):e202302247.
- Zhang J, Liu X, Rao L, Ma R, Wu W, Chen C, Lin Y*. Adverse obstetric and perinatal outcomes of patients with history of recurrent miscarriage: a retrospective cohort study. Fertility and Sterility 2023. https://doi.org/10.1016/j.fertnstert.2023.04.028
- Zhu Y, Liu X, Xu Y, Lin Y*. Hyperglycemia disturbs trophoblast functions and subsequently leads to failure of uterine spiral artery remodeling. Frontiers in Endocrinology 2023, 14:1060253. doi: 10.3389/fendo.2023.1060253
- Wu F, Tian F, Qin C, Qin X, Zeng W, Liu X, Chen C, Lin Y*. Peroxiredoxin2 regulates trophoblast proliferation and migration through SPIB-HDAC2 pathway. Experimental Cell Research 2023, 422:113428. https://doi.org/10.1016/j.yexcr.2022.113428
- Wei XW, Zhang YC, Wu F, Tian FJ, Lin Y*. The role of extravillous trophoblasts and uterine NK cells in vascular remodeling during pregnancy. Frontiers in Immunology 2022, 13:951482. Doi:10.3389/fimmu.2022.951482
- Ren J, Zeng W, Tian F, Wu F, Zhang S, Liu X, Lin Y*. Differential gene expression profile in monocytic myeloid-derived suppressor cells at maternal-fetal interface in a mouse model of spontaneous abortion. J Cell Physiol 2019;234:10789-10799.
- Zhang J, Mo HQ, Tian FJ, Zeng WH, Liu XR, Ma XL, Li X, Qin S, Fan CF, Lin Y*. EIF5A1 promotes trophoblast migration and invasion via ARAF-mediated activation of the integrin/ERK signaling pathway. Cell Death and Disease 2018; 9(9): 926. Doi:10.1038/s41419-018-0971-5
- Lin Y*, Liang Z, Chen Y, Zeng Y. TLR3-involved modulation of pregnancy tolerance in double-stranded RNA-stimulated NOD/SCID mice. J Immunol 2006; 176 (7): 4147-4154.
- 01/01/2022-12/31/2025
National Natural Science Foundation of China, ￥540,000, 82171669
TTP-KDM3A/CYP19A1 signaling on trophoblast differentiation and invasion
Role: Project leader - 01/01/2020-12/31/2023
National Natural Science Foundation of China, ￥550,000, 81971403
Abnormal EVT invasion and pregnancy failure
Role: Project leader - 07/01/2018-06/30/2022
The National Key Research and Development Program of China,￥15,000,000, 2018YFC1002800
Etiology, prevention and treatment of spontaneous abortion at the early-stage of gestation
Role: Project leader - 01/01/2017-12/31/2020
National Natural Science Foundation of China, ￥600,000, 31671567
Effects of stathmin-1 on trophoblast proliferation and migration
Role: Project leader - 01/01/2012-12/31/2015
National Funds for Distinguished Young Scientists, China, ￥2,000,000, 81125004
Obstetrics and Gynecology: Feto-maternal recognition, tolerance and related diseases
Role: Project leader - 01/01/2012-12/31/2015
National Natural Science Foundation of China, ￥600,000, 31171439
Decidual NK cell function and pregnancy tolerance
Role: Project leader - 01/01/2009-12/31/2011
National Natural Science Foundation of China, ￥320,000, 30872761
Regulatory NK cell and pregnancy tolerance
Role: Project leader - 01/01/2007-12/31/2009
National Natural Science Foundation of China, ￥280,000, 30672231
Toll-like signaling and pregnancy tolerance
Role: Project leader
