LI Chunyan  

  • Doctoral Supervisor, Associate Chief Physician
  • Department: ENT & HN Surgery
  • Research Area: Otolaryngology
  • Research Interests: Auditory neuropathy; sensorineural hearing loss; Tympanitis; Drug development
  • Contact: 7250012693@shsmu.edu.cn
  • Associate chief physician,  Shanghai Sixth People’s Hospital, 2022
  • Associate professor, Shanghai Jiao Tong University, 2019
  • Attending physician,  Shanghai Sixth People’s Hospital, 2015
  • Physician, Shanghai Sixth People’s Hospital, 2011                                                                  
  • PhD from Shanghai Jiao Tong University, 2011
  • Youth Vice Chairman, Shanghai Medical Association Hearing and Vestibular Branch
  • Vice Chairman, The Hearing Medicine Innovation and Transformation Committee of the China Hearing Medicine Development Foundation
  1. Zhu YiDan, Ma XiYing, Li LinPeng, Yang QuanJun, Jin Fei, Chen ZhengNnong, Wu CuiPing, Shi HaiBo, Feng ZhangQi, Yin ShanKai, Li ChunYan#.  Surface Functional Modification by Ti(3) C(2) T(x) MXene on PLLA Nanofibers for Optimizing Neural Stem Cell Engineering. Adv Healthc Mater. 2023 Oct;12(25):e2300731. doi: 10.1002/adhm.202300731. Epub 2023 Jul 6.
  2. Cui, Yaqi; Cuiping Wu;Linpeng Li; Haibo Shi; Li Chunyan #, Shankai Yin;Toward nanotechnology-enabled application of bilirubin in the treatment and diagnosis of various civilization diseases, Mater Today Bio. 2023 May 4;20:100658. 
  3. Wu, Cuiping,;Yuefan Jin; Yaqi Cui;Yidan Zhu; Shankai Yin, Li Chunyan # ;Effects of bilirubin on the development and electrical activity of neural circuits, Front Cell Neurosci. 2023 Mar21;17:1136250. 
  4. Li Chunyan #; Zhiyuan Xiong; Lei Zhou;Weiluo Huang;Yushi He; Linpeng Li; Haibo Shi; Jiayu Lu; Jian Wang, Dan Li, Shankai Yin;Interfacing Perforated Eardrums with Graphene-Based Membranes for Broadband Hearing Recovery, Adv Healthc Mater. 2022 Oct;11(20):e2201471.
  5. Linpeng Li; Cuiping Wu;Yong Ling; Chengyi Hou; Qinghong Zhang; Yaogang Li; Haibo Shi; Hongzhi Wang; Li Chunyan # ; Shankai Yin; A nanobrush-shearing strategy enabling the alignment of 1D nanomaterials for synchronous electrochromic actuators and controlled growth of neural stem cells, Materials Today Nano. Volume 20, December 2022, 100256.
  6. Yaoqian Liu; Cuiping Wu; Tingting Chen; Qiyue Shen;Yuanping Xiong; Zhengnong Chen;  Li Chunyan #; Evaluation of acoustic changes in and the healing outcomes of rat eardrums with pars tensa and pars flaccida perforations, Laryngoscope Investig Otolaryngol. 2022 Apr 22;7(3):816-824. 
  7. Li Chunyan #; Zhou Huiqun; Feng Yanmei; Zhao Yan; Wang Jingjing; Chen Zhengnong; Yin Shankai ; Coagulation States in Patients With Sudden Sensorineural Hearing Loss Evaluated by Thromboelastography, Otolaryngol Head Neck Surg, 2021.Jun, 164(6): 1280-1286                                
  8. Li Xinyi; Yu Dongzhen; Jie Huiqun; Zhou Huiqun; Ye Haibo; Ma Guo; Wan Lili; Li Chunyan #; Shi Haibo; Yin Shankai ; Cytochrome P450 1A2 Is Incapable of Oxidizing Bilirubin Under Physiological Conditions, Front Pharmacol, 2019.Oct, 10:1220      
  9. Han Guoying; Li Chunyan #; Shi Haibo; Wang jiping; Su Kaiming; Yin Xinlu; Yin Shankai ; Riluzole is a Promising Pharmacological Inhibitor of Bilirubin-Induced Excitotoxicity in the Ventral Cochlear Nucleus., CNS Neurosci Ther, 2015.Mar, 21(3): 262-70 
  • 01/01/2024-12/31/2026
    National Natural Science Foundation of China Excellent Youth Program, ¥200,000,000, 82322020
    Auditory function repair 
    Role: Project leader                                                                                                                  
  • 11/01/2023-10/31/2026
    National Key Research and Development Program for Young Scientists ¥90,000,000, 2023YFC2509800
    Establishment of innovative diagnosis and treatment system and key technology research for intractable inner ear diseases
    Role: Principal Investigator                                                                                                                                             
  • 01/01/2021-12/31/2024          
    National Natural Science Foundation of China General Project, ¥55,000,000, 82071042          
    The key role and mechanism of WNK1 phosphorylation in bilirubin induced auditory central neurotoxicity
    Role: Project leader    
  • 01/01/2015-12/31/2018
    National Natural Science Foundation of China General Project, ¥73,000,000, 81470688       
    The role of cytochrome P450 oxidases (CYP) in the mechanisms of age dependence and auditory pathway specific of bilirubin neurotoxicity 
    Role: Project leader    
  • 01/01/2012-12/31/2014
    National Natural Science Foundation of China Excellent Youth Program, ¥22,000,000, 81100718
    The role of GABA/glycinergic synaptic transmission in bilirubin excitotoxicity of auditory center and the intervention 
    Role:Project leader