ZHAO Shichang  

  • Graduate Supervisor, Associate Chief Physician
  • Department: Orthopedics
  • Research Area: Orthopedics / Spinal Surgery
  • Research Interests: Spinal trauma, limb trauma, cervical spondylosis, lumbar disc herniation, nonunion, and bone infection
  • Contact: zhaoshichang@sjtu.edu.cn
  • Associate Chief Physician, Shanghai Sixth People's Hospital, SJTU School of Medicine, 2024-present
  • Attending Physician, Shanghai Sixth People's Hospital, SJTU School of Medicine, 2018-2023
  • Resident, Shanghai Sixth People's Hospital, SJTU School of Medicine, 2015-2017
  • PhD, Shanghai Jiao Tong University, 2015
  • MSc, Shanghai Jiao Tong University, 2012
  • BS, Wuhan University of Science and Technology, 2009
  • Associate Chief Physician, Department of Orthopedics, Shanghai Sixth People's Hospital, 2024-present
  • Attending Physician, Department of Orthopedics, Shanghai Sixth People's Hospital, 2018-2023
  • Resident Physician, Department of Orthopedics, Shanghai Sixth People's Hospital, 2015-2017
  1. Tian H, Ding B, Zeng Z, Zhao S, Zhao J. What lies beneath early-onset disc degeneration. Ann Rheum Dis. 2025 Oct 11:S0003-4967(25)04324-9.  (IF= 20.600)
  2. Yifan Shen#, Guanzhe Xu#, Huanxuan Huang#, Kaiyang Wang, Hui Wang, Meidong Lang*, Hong Gao*, Shichang Zhao*. Sequential Release of Small Extracellular Vesicles from Bilayered Thiolated Alginate/Polyethylene Glycol Diacrylate Hydrogels for Scarless Wound Healing. ACS Nano. 2021;15: 6352-6368. (IF= 16.400) 
  3. Peng Pei#, Hongxing Hu#, Ying Chen#, Shangfeng Wang, Jing Chen, Jiang Ming, Yiwei Yang, Caixia Sun, Shichang Zhao*, Fan Zhang*. NIR-II Ratiometric Lanthanide-Dye Hybrid Nanoprobes Doped Bioscaffolds for In Situ Bone Repair Monitoring. Nano Lett. 2022, 22, 783-791. (IF=12.2625) 
  4. Tang Yunfeng, Deng Xiangtian, Yi Min, Wang Dong, Zheng Cheng*, Zhao Shichang*, Zhao Renliang*. Dual-pathway nanoengineering: spatiotemporal control of immunogenic apoptosis and macrophage phenotype reprogramming for augmented antitumor immunity. J Nanobiotechnology. 2025 Dec 7;s12951-025-03882-1. (IF= 12.600) 
  5. Hu Hongxing#, Dong Lanlan#, Bu Ziheng, Shen Yifan, Luo Jian, Zhang Hang, Zhao Shichang*, Lv Fang*, Liu Zhongtang*. miR-23a-3p-abundant small extracellular vesicles released from Gelma/nanoclay hydrogel for cartilage regeneration. Journal of Extracellular Vesicles. 2020;9: 1778883 (IF= 11) 
  6. Huang Jinghuan#, Yu Muyu#, Yin Wenjing, Liang Bo, Li Ang, Li Jingfeng, Li Xiaolin*, Zhao Shichang*, Liu Fang*. Development of a novel RNAi therapy: Engineered miR-31 exosomes promoted the healing of diabetic wounds. Bioactive Materials. 2021; 2841–2853  (IF= 20.300) 
  7. Renliang Zhao#, Lianghua Jiang#, Juan Du#, Bitong Xu, Ang Li, Wei Wang*, Shichang Zhao*, Xiaolin Li*. Fluffy sponge-reinforced electrospun conduits with biomimetic structures for peripheral nerve repair. Composites Part B. 230 (2022) 109482. (IF=9.078) 
  8. Yanlong Kong#, Lei Zhou#, Shiyang Liao #, Changping Wang , Jing Chen , Xiaopan Cai *, Shichang Zhao*, Dianwen Song*, Yadong Zhang*. Dual peptide-engineered and gadolinium-doped polydopamine particles as targeted nanotheranostics for the treatment of osteosarcoma and related osteolysis. Chemical Engineering Journal. 444 (2022) 136516. (IF=8.355) 
  9. Renliang Zhao#, Yifan Shen#, Xiangtian Deng#, Yunfeng Tang, Zilu Ge, Dong Wang, Zhencheng Xiong, Qian Fang, Zhen Zhang, Xiaolin Li, Xiaotian Du, Wei Lin*, Shichang Zhao*, Guanglin Wang*. From brain to bone: Harnessing extracellular vesicles released from TBI to enhance osteogenesis by 3D-Printed hydrogel scaffold. Composites Part B 264 (2023) 110909. (IF=9.078) 
  10. Xuan Huixia, Hu Haoran, Geng Congying, Song Jianchun, Shen Yifan, DongLei, QingbaoGuan, Zhao Shichang*,You Zhengwei*. Biofunctionalized chondrogenic shape-memory ternary scaffolds for efficient cell-free cartilage regeneration. Acta Biomaterialia.2020;105:97-110.(IF= 6.638) 
  • 01/01/2020-12/31/2023
    National Natural Science Foundation of China (General Program), ¥600,000, 51972212
    Engineered miR-7b-overexpressing umbilical cord mesenchymal stem cell exosomes combined with hierarchically structured borate bioactive glass scaffolds for the treatment of steroid-induced osteonecrosis of the femoral head
    Role: Principal Investigator
  • 01/01/2017-12/31/2019
    National Natural Science Foundation of China (Youth Program), ¥170,000, 81601886
    3D-printed MBG scaffolds loaded with iPS-MSCs-derived extracellular vesicles activating AMPK-ERK1/2 signaling pathway for the treatment of large segmental bone defects
    Role: Principal Investigator
  1. [Shichang Zhao] (2025), "Spinal surgical curette device with integrated cold light source", CN202520588200.7
  2. [Shichang Zhao] (2025), "Bone grafting device with controllable depth and angle for spinal surgery", CN202520830216.4
  3. [Shichang Zhao] (2025), "Broken screw or wire extraction device for spinal surgery", CN202522119183.5
  4. [Shichang Zhao] (2025), "Specialized skin incision scalpel for minimally invasive percutaneous pedicle screw fixation in spinal surgery", CN202520408628.9
  5. [Shichang Zhao] (2025), "Gantry-type thoracolumbar fracture reduction device", CN202521124277.5

Academic Affiliations:
- Member of AO/ASIF (Association for the Study of Internal Fixation)
- Member of Bioceramics Branch, Chinese Society for Biomaterials