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LIU Suru  

  • Chief Physician, Graduate Supervisor
  • Department: ENT and HN Surgery
  • Research Area: Sleep Medicine  Obstructive Sleep Apnea (OSA)
  • Research Interests: Sleep Medicine; Obstructive Sleep Apnea (OSA); Drug-Induced Sleep Endoscopy (DISE); Upper airway surgery; Metabolic and cardiovascular consequences of OSA.
  • Contact: suruliu2011@163.com
Biography Positions Publications Research Projects
  • MD & PhD in Otorhinolaryngology from Shanghai Jiao Tong University (2012).
  • Visiting Scholar at Stanford University Sleep Medicine Center (2019-2020). 
  • Currently Chief Physician at Shanghai Sixth People's Hospital. 
  • Chief Physician, Shanghai Sixth People's Hospital
  • Vice Chairman & Secretary, Sleep Breathing Disorder Committee Chinese Association of Integrative Medicine Otorhinolaryngology:
  • Standing Committee Member, Voice Committee, Chinese Association of Integrative Medicine Otorhinolaryngology Head and Neck Surgery;
  • Editorial Board Member, Chinese Journal of Otorhinolaryngology in Integrative Medicine
  • Editorial Board Member, Chinese Medical Digest: Otorhinolaryngology
  1. Li C, Zhou Z, Zhang X, Zhou E, Zhou T, Zhang J, Li X, Zou J, Xu H, Guan J, Liu Y, Liu S, Zhu X, Huang W, Yi H, Yin S. Increased sleep apnea-specific hypoxic burden is independently associated with cardiovascular autonomic dysfunction in obstructive sleep apnea: A large-scale study. Sleep Med. 2025 Oct 17;136:106863. doi: 10.1016/j.sleep.2025.106863. Epub ahead of print. PMID: 41130142.
  2. Dong L, Yi H, Liu S*. Xanthoma disseminatum leading to laryngeal obstruction. Clin Exp Dermatol. 2025 Jul 24;50(8):1639-1640. doi: 10.1093/ced/llaf127. PMID: 40091609. 
  3. Wu C, Liu S#, Zhou L, Chen Z, Yang Q, Cui Y, Chen M, Li L, Ke B, Li C, Yin S. Cellular and Molecular Insights into the Divergence of Neural Stem Cells on Matrigel and Poly-l-lysine Interfaces. ACS Appl Mater Interfaces. 2024 Jun 26;16(25):31922-31935. doi: 10.1021/acsami.4c02575. Epub 2024 Jun 14. PMID: 38874539; PMCID: PMC11212020. 
  4. Huang W, Zhang J, Zou J, Wang X, Xu H, Guan J, Yi H*, Liu S*, Yin S. Fibroblast growth factor 21 is an independent predictor of prevalent and incident obstructive sleep apnea. iScience. 2023 Jan 14;26(2):105985. doi: 10.1016/j.isci.2023.105985. PMID: 36798439; PMCID: PMC9926096.
  5. Zhou EH, Liu SR#, Zhu HM, Yi HL, Chen XP.  Management and postoperative   use of double-cannula irrigation-drainage tube in cervical necrotizing fasciitis: a Chinese single-institution experience of 46 patients. Eur Arch Otorhinolaryngol. 2021 Aug;278(8):2975-2981. (Co-First Author)
  6. Liu SR#, Yi HL*, Yin SK, Guan J, Chen B, Meng LL, Su KM* Associated predictors of therapeutic response to uvulopharyngopalatoplasty for severe obstructive sleep apnea hypopnea syndrome Eur Arch Otorhinolaryngol. 2013 270(4):1411-7 
  7. Liu SR#, Yi HL*, Guan J, Chen B, Wu HM, Yin SK*. Changes in facial appearance after maxillomandibular advancement for severe obstructive sleep apnea hypopnea syndrome in Chinese patients: a subjective and objective evaluation. Int J Oral Maxillofac Surg.  2012.  41(9):1112-9. 
  8. Liu SR#, Yi HL*, Yin SK, Guan J, Chen B, Meng LL, Zou JY, Zhang WT* Primary Maxillomandibular Advancement With Concomitant Revised Uvulopalatopharyngoplasty With Uvula Preservation for Severe Obstructive Sleep Apnea-Hypopnea Syndrome. J Craniofac Surg. 2012.23(6):1649-53.
  9. Xu H, Liu Y, Li C, Li X, Shen L, Wang H, Liu F, Zou J, Xia Y, Huang W, Liu Y, Gao Z, Fu Y, Wang F, Huang S, Song Z, Song F, Gao Y, Peng Y, Zou J, Zhu H, Liu S, Li L, Zhu X, Xiong Y, Hu Y, Yang J, Li Y, Gao F, Guo Q, Huang H, Zhang W, Li J, Chen Y, Dong P, Yang J, Lv J, Wang P, Sun Y, Qian B, Yaffe K, Guan J, Yi H, Leng Y, Yin S. Effects of CPAP on Neuroimaging Biomarkers and Cognition in Adult OSA: A Randomized Controlled Trial. Am J Respir Crit Care Med. 2025 Feb 25. doi: 10.1164/rccm.202406-1170OC. Epub ahead of print. PMID: 39998447.
  10. Xu H, Liu F, Li Z, Li X, Liu Y, Li N, Zhang X, Gao Z, Zhang X, Liu Y, Zou J, Meng L, Liu S, Zhu H, Tang X, Wu H, Su K, Chen B, Yu D, Ye H, Chen H, Yi H, Yin S, Guan J, Shi Y. Genome-Wide Association Study of Obstructive Sleep Apnea and Objective Sleep-related Traits Identifies Novel Risk Loci in Han Chinese Individuals. Am J Respir Crit Care Med.2022Dec15;206(12):1534-1545.
  • 01/01/2025-01/01/2029: 
    National S&T Major Project (Innovation 2030) -  ¥1,000,000.  (2024ZD0529200)Research on Novel Diagnostic and Therapeutic Technologies for Sleep-Disordered Breathing.
    Role: Project Key Member, Sub-center Lead.
  • 01/09/2025-31/08/2028: 
    Shanghai Sixth People's Hospital General Cultivation Project -¥300,000. Mechanism of Ceruloplasmin-Copper Metabolism Disorder in Chronic Intermittent Hypoxia-Mediated Metabolic Liver Injury.
    Role: Role: Project leader 
  • 01/01/2023.01/12/2026:
    National Natural Science Foundation General Project - *Study on the Role and Mechanism of GASP-1 Regulating Genioglossus Function via Myostatin Signaling Pathway*. (82371131/H1302)
    Role: Participant.
  • 2016.01-2018.12:
    National Natural Science Foundation Youth Project - ¥216,000 CNY   (81500780/H1302) *FGF-21 Activates PI3K/AKT Signaling Pathway to Regulate Muscle Fiber Transformation in Genioglossus*.
    Role: Project leader. 

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