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XIA Yu
- Graduate Supervisor, Professor
- Department: Obstetrics and Gynecology
- Research Area: Maternal-Fetal Medicine
- Research Interests: Pathogenic Mechanisms of Immunogenic Disorders in Pregnancy
- Contact: 7250003761@shsmu.edu.cn
- Postdoc from Second Military Medical University, 2012
- PhD from Shandong University, 2008
- Professor, Department of Obstetrics and Gynecology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
- Song M, Wang J, Mu W, Zheng Y, Jiang R, Cai Y, Teng Y, Xia Y#. Inhibition of FKBP5 alleviates obstetric antiphospholipid syndrome by regulating macrophage polarization. Sci Rep. 2025, doi: 10.1038/s41598-025-25472-9.
- Song M, Wang J, Mu W, Zheng Y, Cai Y, Liu J, Xia Y#. MiR-30d-5p Modulates Glucose and Lipid Metabolism by Targeting CD73 through the AMPK Pathway. Cell Biochem Biophys. 2025, doi: 10.1007/s12013-025-01815-1.
- Xia Y*, Liu X*, Mu W, Ma C, Wang L, Jiao Y, Cui B, Hu S, Gao Y, Liu T, Sun H, Zong S, Liu X, Zhao Y. Capturing 3D Chromatin Maps of Human Primary Monocytes: Insights From High-Resolution Hi-C. Front Immunol. 2022, doi: 10.3389/fimmu.2022.837336. eCollection 2022.
- Liu J, Zhang L, Tian Y, Wan S, Hu M, Song S, Zhang M, Zhou Q, Xia Y#, Wang X#. Protection by hydroxychloroquine prevents placental injury in obstetric antiphospholipid syndrome. J Cell Mol Med. 2022, doi: 10.1111/jcmm.17459. Epub 2022 Jun 29.
- Lu Y, Dong Y, Zhang Y, Shen D, Wang X, Ge R, Zhang M, Xia Y#, Wang X#. Antiphospholipid antibody-activated NETs exacerbate trophoblast and endothelial cell injury in obstetric antiphospholipid syndrome. J Cell Mol Med. 2020 Jun;24(12):6690-6703. doi: 10.1111/jcmm.15321.
- Zhou Q, Lian Y, Zhang Y, Li L, Li H, Shen D, Zhou Y, Zhang M, Lu Y, Liu J, Xia Y#, Wang X#. Platelet-derived microparticles from recurrent miscarriage associated with antiphospholipid antibody syndrome influence behaviours of trophoblast and endothelial cells. Mol Hum Reprod. 2019, doi: 10.1093/molehr/gaz019.
- 01/01/2022-12/31/2025
National Natural Science Foundation of China,¥,540,000,82171665
Mechanism underlying the action of FKBP5 on participation in pathogenesis of OAPS via regulation of Treg cells
Role: Project leader
