TAO Shicong  

  • Graduate Supervisor, Associate Researcher
  • Department: Orthopedics
  • Research Area: Regenerative and Rehabilitative Medicine
  • Research Interests: Microenvironment Modulation Strategies for Osteochondral Regeneration
  • Contact: sctao@shsmu.edu.cn
  • MD from Shanghai Jiao Tong University School of Medicine, 2017
  • Associate Researcher, Department of Orthopedics, Shanghai Sixth People’s Hospital
  • Attending Physician, Department of Orthopedics, Shanghai Sixth People’s Hospital
  1. He, S.-H.#, Shen, Z.-H.#, Zhang, R.#, Liu, P.-L., Li, X.-R., Deng, Q.-S., Zhang, Y.-C., Wang, A., Dou, X.-Q., Guo, S.-C.* and Tao, S.-C.* (2025), Kartogenin-Loaded Aminated Hollow Mesoporous Prussian Blue Nanozyme-Reinforced Hydrogel Remodels the Senescent Microenvironment via Reactive Oxygen Species Scavenging and Stimulator of Interferon Genes Inhibition to Promote Cartilage Regeneration. Small Struct., 6: 2400592. https://doi.org/10.1002/sstr.202400592
  2. Li XR#, Deng QS#, He SH#, Liu PL, Gao Y, Wei ZY, Zhang CR, Wang F, Zhu TH, Dawes H, Rui BY, Tao SC*, Guo SC*. 3D cryo-printed hierarchical porous scaffolds provide immobilization of surface-functionalized sleep-inspired small extracellular vesicles: synergistic therapeutic strategies for vascularized bone regeneration based on macrophage phenotype modulation and angiogenesis-osteogenesis coupling. J Nanobiotechnology. 2024 Dec 19;22(1):764. doi: 10.1186/s12951-024-02977-5
  3. Liu PL#, He SH#, Shen ZH#, Li XR, Deng QS, Wei ZY, Zhang CR, Dou XQ, Zhu TH, Dawes H, Lu J, Guo SC*, Tao SC*. Bilayer Scaffolds Synergize Immunomodulation and Rejuvenation via Layer-Specific Release of CK2.1 and the "Exercise Hormone" Lac-Phe for Enhanced Osteochondral Regeneration. Adv Healthc Mater. 2024 Nov 12:e2402329. doi: 10.1002/adhm.202402329
  4. QS. Deng#, XR. Li#, PL. Liu#, SH. He, Y. Gao, ZY. Han, ZH. Shen, ZY. Wei, CR. Zhang, F. Wang, H. Dawes, TH. Zhu, SC. Guo*, SC. Tao*, 3D Cryo-Printed Hierarchical Porous Scaffolds Harmonized with Hybrid Nanozymes for Combinatorial Mitochondrial Therapy: Enhanced Diabetic Bone Regeneration via Micromilieu Remodeling. Adv. Funct. Mater. 2024, 2403145. https://doi.org/10.1002/adfm.202403145
  5. Deng QS#; Gao Y#; Rui BY#; Li XR; Liu PL; Han ZY; Wei ZY; Zhang CR; Wang F; Dawes H; Zhu TH; Tao SC*; Guo SC*; Double-network hydrogel enhanced by SS31-loaded mesoporous polydopamine nanoparticles: Symphonic collaboration of near-infrared photothermal antibacterial effect and mitochondrial maintenance for full-thickness wound healing in diabetes mellitus, Bioact Mater, 2023, 27: 409-428.
  • 01/2025–12/2028
    National Natural Science Foundation of China (General Program), ¥480,000, 82472595
    Low-Intensity Pulsed Ultrasound and Exosome-Mediated Delivery of DAXX-PROTAC Modulate the Joint Microenvironment for the Treatment of Diabetic Osteoarthritis
    Role: Principal Investigator
  • 01/2019–12/2021
    National Natural Science Foundation of China (Young Scientists Fund), ¥210,000, 81802226
    Exosomes carrying circ77 act as competing endogenous RNA to regulate the function of chondrocytes: a potential treatment for osteoarthritis
    Role: Principal Investigator
  1. [Shicong Tao, Shangchun Guo] (2024), “Exosome Filtration and Extraction Device and Exosome Extraction Method”, ZL201910675500.8
  2. [Shicong Tao, Shangchun Guo] (2024), “Deep Learning–Based System and Method for Identifying Exosome TEM Images”, ZL201911060639.8
  3. [Shicong Tao, Shangchun Guo] (2025), “Visualized Acetabular Prosthesis Implantation Device”, ZL201911061736.9