HUANG Yu  

  • Graduate Supervisor, Associate Professor
  • Department: Radiology
  • Research Area: Imaging and Nuclear Medicine (Radiology)
  • Research Interests: Nano-pharmaceuticals for diagnosis and treatment of thrombotic diseases and cancers
  • Contact: yuhuang6y@163.com
  • Postdoc from Imperial College London, 2021
  • PhD from Shanghai Jiao Tong University, 2017
  • MSc from Shanghai Jiao Tong University, 2013
  • Associate Professor, Department of Radiology, Shanghai Sixth People’s Hospital
  1. Yu Huang, Boram Gu, Isabelle Salles, Kirk A Taylor, Li Yu, Jie Ren, Colin Longstaff, Alun D. Hughes, Simon A. Thom, Xiao Yun Xu, Rongjun Chen. Fibrinogen-mimicking, multiarm nanovesicles for human thrombus-specific delivery of tPA and targeted thrombolytic therapy. Science Advances, 2021, 7, eabf9033.
  2. Yu Huang*, Jingxuan Jiang, Jie Ren, Yuanyuan Guo, Qianqian Zhao, Jia Zhou, Yuehua Li, Rongjun Chen, A fibrinogen-mimicking, activated-platelet-sensitive nanocoacervate enhances thrombus targeting and penetration of tissue plasminogen activator for effective thrombolytic therapy. Advanced Healthcare Materials, 2022, 21, 2201265. (*corresponding author)
  3. Yu Huang, Li Yu, Jie Ren, Boram Gu, Colin Longstaff, Alun D. Hughes, Simon A. Thom, Xiao Yun Xu, Rongjun Chen. An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy. Journal of Controlled Release, 2019, 300, 1-12.
  4. Yu Huang, Feng Qiu, Lingyue Shen, Dong Chen, Yue Su, Chao Yang, Bo Li, Deyue Yan, Xinyuan Zhu. Combining two-photon-activated FRET and near-infrared photothermal effect of unimolecular micelles for enhanced photodynamic therapy. ACS Nano, 2016, 10, 10489.
  5. Yu Huang, Feng Qiu, Dong Chen, Lingyue Shen, Shuting Xu, Dongbo Guo, Yue Su, Deyue Yan, Xinyuan Zhu. Color-convertible unimolecular micelle-based activatable fluorescent probe for tumor-specific detection and imaging in vitro and in vivo. Small, 2017, 13, 1604062.
  6. Dongbo Guo, Yu Huang*, Xin Jin, Chuan Zhang, Xinyuan Zhu*. A redox-responsive, in-situ polymerized polyplatinum(IV)-coated gold nanorod as an amplifier of tumor accumulation for enhanced thermo-chemotherapy. Biomaterials, 2021, 266, 120400. (*corresponding author)
  7. Jiahua Wang*, Manzar Abbas, Yu Huang*, Junyou Wang, Yuehua Li*, Redox-responsive peptide-based complex coacervates as delivery vehicles with controlled release of proteinous drugs. Communications Chemistry, 2023, 7402496. (*corresponding author)
  8. Wang Li, Youlong Hai, Ranxing Yang, Kun Zheng, Jinlong Yu, Hong Xie*, Yu Huang*, Kai Ni*. Innovations in 3D printing technology for infection prevention applications in medical implants: antimicrobial materials and biointerface engineering. International Journal of Bioprinting, 2024, 03, 2338. (*corresponding author)
  9. Yu Huang, Lingyue Shen, Dongbo Guo, Wumaier Yasen, Dong Chen, Yan Wu, Yue Su, Feng Qiu, Deyue Yan, Xinyuan Zhu. A NIR-triggered gatekeeper of supramolecular conjugated unimicelles with two-photon absorption for controlled drug release. Chemical Communications, 2019, 55, 6735-6738.
  10. Yu Huang, Zewei Wang, Guiju Zhang, Yuanxi Yang, Li Yu, Jie Ren, Rongjun Chen. A pH/Redox-dual responsive, nanoemulsion-embedded hydrogel for efficient oral delivery and controlled release of magnesium ions. Journal of Materials Chemistry B, 2021, 9, 1888-1895.
  1. [Rongjun Chen, Yu Huang, Xiao Yun Xu, Simon A. Thom] (2022), “Red blood cell-derived vesicles”, PCT/GB2020/053276.       
  2. [Rongjun Chen, Yu Huang, Xiao Yun Xu, Simon A. Thom] (2020), “Long-circulating RBC-derived vesicles for tPA delivery”, AXH/RXF/94126GB1.  
  3.  [Xinyuan Zhu, Yu Huang] (2018), “Preparation and application of H2O2-responsive fluorescent conjugated polymer ”, ZL201510818276.5.                                                                                                                                                                                                                  

Honors and Awards: 

  • 2023 Shanghai Jiao Tong University School of Medicine Excellent Youth Class Outstanding Student Award
  • 2021 Shanghai Overseas Leading Talents
  • 2021 Shanghai Pujiang Talents
  • 2020 Sir William Wakeham Award
  • 2020 Oral Presentation Award in Postdoctoral Symposium
  • 2019 Travel Award in ISFP