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HUANG Xinyu
- Doctoral Supervisor, Professor
- Department: General Surgery
- Research Area: Surgery (General Surgery)
- Research Interests: Pancreatic ductal adenocarcinoma, and liver cancer
- Contact: 18930177490@163.com
- MD from Medical College of Nanchang University, 1986
- PhD from Shanghai Jiao Tong University, 2010
- Director, Department of General Surgery, Shanghai Sixth People's Hospital
- Vice Chairman, Pancreatic Surgery of Shanghai Assosiation of Chinese Intergrative Medicine
- Xia G, Wang H, Song Z, Meng Q, Huang X, Huang X. Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2). J Exp Clin Cancer Res. 2017 Aug 10;36(1):107. doi: 10.1186/s13046-017-0579-0.
- Xia G, Zhang H, Cheng R, Wang H, Song Z, Deng L, Huang X, Santos HA, Cui W. Localized Controlled Delivery of Gemcitabine via Microsol Electrospun Fibers to Prevent Pancreatic Cancer Recurrence. Adv Healthc Mater. 2018 Sep;7(18):e1800593. doi: 10.1002/adhm.201800593.
- Zhu Y, Wang Y, Xia G, Zhang X, Deng S, Zhao X, Xu Y, Chang G, Tao Y, Li M, Li H, Huang X, Chan HF. Oral Delivery of Bioactive Glass-Loaded Core-Shell Hydrogel Microspheres for Effective Treatment of Inflammatory Bowel Disease. Adv Sci (Weinh). 2023 Jun;10(18):e2207418. doi: 10.1002/advs.202207418.
- Wang H, Liu Y, Wang Y, Xu T, Xia G, Huang X. Umbelliprenin induces autophagy and apoptosis while inhibits cancer cell stemness in pancreatic cancer cells. Cancer Med. 2023 Jul;12(14):15277-15288. doi: 10.1002/cam4.6170.
- Wangpu X, Zhao J, Yu C, Yu S, Wang H, Yuan Z, Huang X. CircATP13A1 (hsa_circ_0000919) promotes cell proliferation and metastasis and inhibits cell apoptosis in pancreatic ductal adenocarcinoma via the miR-186/miR-326/HMGA2 axis: implications for novel therapeutic targets. Am J Cancer Res. 2023 Nov 15;13(11):5610-5625.
- Wang H, Wang J, Liu J, Wang Y, Xia G, Huang X. Jumonji-C domain-containing protein 5 suppresses proliferation and aerobic glycolysis in pancreatic cancer cells in a c-Myc-dependent manner. Cell Signal. 2022 May;93:110282. doi: 10.1016/j.
- Wang H, Zhao Z, Lei S, Li S, Xiang Z, Wang X, Huang X, Xia G, Huang X. Gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive oxygen species. Cancer Cell Int. 2019 Jan 5;19:7. doi: 10.1186/s12935-018-0705-x.
- Song Z , Ma Y , Xia G , Wang Y , Kapadia W , Sun Z , Wu W , Gu H , Cui W , Huang X . In vitro and in vivo combined antibacterial effect of levofloxacin/silver co-loaded electrospun fibrous membranes. J Mater Chem B. 2017 Sep 28;5(36):7632-7643. doi: 10.1039/c7tb01243h.
- 01/12/2019-01/12/2021
National Key Research and Development Program of China, ¥1,940,000, 2019YFC0120400
Industrialization of panoramic composite digital laparoscopy
Role: Project leader - 01/06/2018-01/06/2021
National Key Research and Development Project, ¥200,000,18ZR1429100
The research of microenvironment-responsive nanodrug-loaded fibrous membrane inhibiting postoperative recurrence of pancreatic cancer and its mechanism
Role: Project leader
