Search

Close
Research
Home > Research > Faculty
Research

HE Aina  

  • Chief Physician, Graduate Supervisor
  • Department: Oncology
  • Research Area: Oncology
  • Research Interests: Tumor organoids and immune microenvironment
  • Contact: anna_1188@126.com
Biography Positions Publications Patents
  • Chief physician, Department of Oncology, Shanghai Sixth People's Hospital, 2022
  • Postdoc, Department of Urology, Boston Children's Hospital, Harvard Medical School, 2017
  • Postdoc, Department of Genetics, Brigham Women's Hospital, Harvard Medical School, 2016
  • Associate chief physician, Department of Oncology, Shanghai Sixth People's Hospital, 2015
  • Attending physician, Department of Oncology, Shanghai Sixth People's Hospital, 2011
  • Physician, Department of Oncology, Shanghai Sixth People's Hospital, 2009
  • MD from Zhejiang University, 2004
  • BA from Zhejiang University, 1999
  • Deputy Director, Department of Oncology, Shanghai Sixth People's Hospital
  1. He A, Tian S, Kopper O, Horan DJ, Chen P, Bronson RT, Sheng R, Wu H, Sui L, Zhou K, Tao L, Wu Q, Huang Y, Shen Z, Han S, Chen X, Chen H, He X, Robling AG, Jin R, Clevers H, Xiang D, Li Z, Dong M#. Targeted inhibition of Wnt signaling with a Clostridioides difficile toxin B fragment suppresses breast cancer tumor growth. PLoS Biol. 2023 Nov 9;21(11):e3002353. doi: 10.1371/journal.pbio.3002353. 
  2. Zhou C#, Wu Y, Wang Z, Liu Y, Yu J, Wang W, Chen S, Wu W, Wang J, Qian G#, He A#. Standardization of organoid culture in cancer research. Cancer Med. 2023 Jul;12(13):14375-14386. doi: 10.1002/cam4.5943. 
  3. Chen G, Gong T, Wang Z, Wang Z, Lin X, Chen S, Sun C, Zhao W, Kong Y, Ai H, Yang H, Liu Y, Wu F, Kang J, Zhao S#, Xiao X#, Sun J#, He A#, Li Z#. Colorectal cancer organoid models uncover oxaliplatin-resistant mechanisms at single cell resolution. Cell Oncol (Dordr). 2022 Dec;45(6):1155-1167. doi: 10.1007/s13402-022-00705-5. 
  4. He A#, Huang Y, Cheng W, Zhang D, He W, Bai Y, Gu C, Ma Z, He Z, Si G, Chen B, Breault DT, Dong M, Xiang D#. Organoid culture system for patient-derived lung metastatic osteosarcoma. Med Oncol. 2020 Oct 20;37(11):105. doi: 10.1007/s12032-020-01429-y.
  5. He A#, Ma L, Huang Y, Zhang H, Duan W, Li Z, Fei T, Yuan J, Wu H, Liu L, Bai Y, Dai W, Wang Y, Li H, Sun Y, Wang Y, Wang C, Yuan T, Yang Q, Tian S, Dong M, Sheng R#, Xiang D#. CDKL3 promotes osteosarcoma progression by activating Akt/PKB. Life Sci Alliance. 2020 Mar 31;3(5):e202000648. doi: 10.26508/lsa.202000648.
  1. [Min Dong, Liang Tao, Rongsheng Jin, Peng Chen, Aina He](2018),“ Compositions and methods for inhibiting Wnt signaling”,  WIPO, 62/618,042
  2. [Aina He, Songxi Xiang, Zhongping Ma, Yiming Wang, Yinglu Han](2021),“A method of in vitro culture of fresh liver tissue sections”，CN202111047988.3
  3. [Siyuan Shao, Rong Zhou, Laiping Zhong, Aina He](2022), “A culture medium and construction method for cervical lymph node metastasis organoids in oral squamous cell carcinoma”，CN202211736456.5
  4. [Dongxi Xiang, Jiaoduan Li, Xiuying Xiao, Aina He](2023), “Application of targeted inhibitors in the treatment and/or prevention of duodenal cancer”，CN202311357962.8
  5. [Dongxi Xiang, Jiaoduan Li, Aina He, Lixin Jiang](2023), “A targeted inhibitor that can effectively inhibit organ metastasis of BAP1 inactivated mutant uveal melanoma”，CN202310685260.6

Copyright © 2024, All Rights Reserved.