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DU Dajiang  

  • Doctoral Supervisor, Professor
  • Department: Orthopedics
  • Research Area: Surgery (Orthopedics)
  • Research Interests: Bone and Cartilage Repair
  • Contact: dudajiang@sjtu.edu.cn
Biography Positions Publications Research Projects Patents
  • PhD(Engineering) from Tokyo University, 2007
  • PhD&MD(Medicine) from Jilin University, 2006
  • Clinical Medicine (7-year program) from Jilin University, 2003
  • Research Fellow, Tokyo University, 2008
  • Visiting Scholar, Osaka University, 2012
  • Visiting Associate Professor, Harvard Medical School, 2013-2015
  • AO Spine Fellow, University of Bern, 2015
  1. Dajiang DU*, Teruo Asaoka, Takashi Ushida, Katsuko Furukawa. Fabrication and perfusion culture of anatomically shaped artificial bone using stereolithography. Biofabrication. 2014 6(4): 045002 
  2. Dajiang Du*, Norihiko Sugita, Zhen Liu, Yu Moriguchi, Ken Nakata, Akira Myoui, and Hideki Yoshikawa. Repairing Osteochondral Defects of Critical Size Using Multiple Costal Grafts: An Experimental Study. Cartilage, 2015 6(4) 241–251 
  3. Dajiang Du, Changqing Zhang*. Two-Incision, Wire-Assisted Achilles Tendon Z-Lengthening: Surgical Technique and Case Report. J Foot Ankle Surg. 2019;58(3):604-606. 
  4. Yiyang Ma，Kaiwen Zheng， Yidan Pang， Fuzhou Xiang，Junjie Gao*，Changqing Zhang*，Dajiang Du*. Anti-hypertrophic effect of synovium-derived stromal cells on costal chondrocytes promotes cartilage repairs. J Orthop Translat. 2022;32：59-68 
  5. Dajiang Du, Zhen Liu, Wanting Niu, Ding Weng, Teck Chuan Lim, Motoichi Kurisawa, Myron Spector. * An Injectable Multifunctional Dual-Phase Bead-Reinforced Gelatin Matrix Permissive of Mesenchymal Stem Cell Infiltration for Musculoskeletal Soft Tissue Repair. Adv Healthc Mater. 2021；10(18): e2100626. 
  6. Kaiwen Zheng, Yiyang Ma, Cheng Qiu, Yidan Pang, Junjie Gao*，Changqing Zhang*，Dajiang Du*. Co-culture pellet of human Wharton's jelly mesenchymal stem cells and rat costal chondrocytes as a candidate for articular cartilage regeneration: in vitro and in vivo study. Stem Cell Res Ther. 2022;13(1):386. 
  7. Changqing Zhang, Dajiang Du, Peichun Hsu, et al. Autologous Costal Cartilage Grafting for a Large Osteochondral Lesion of the Femoral Head: A 1-Year Single-Arm Study with 2 Additional Years of Follow-up. J Bone Joint Surg Am. 2022;104(23):2108-2116. 
  8. Shu Zhao, Guanghui Xu, Jian Wang, Yi Wen, Jinyuan Lu, Baitong Wu, Guangming Wang, Danjing Yang, Bin Ling*, Dajiang Du*, Jun Xu*. Engineering exosomes derived from subcutaneous fat MSCs specially promote cartilage repair as miR-199a-3p delivery vehicles in Osteoarthritis. J Nanobiotechnology. 2023; 21: 341.
  9. Yidan Pang, Yiyang Ma, Kaiwen Zheng, Siyuan Zhu, Hongyu Sui, Hao Ren, Kang Liu, Wei Li, Yigang Huang*, Dajiang Du*, Junjie Gao*, Changqing Zhang*. Costal Cartilage Graft Repair Osteochondral Defect in a Mouse Model. Cartilage. 2023:19476035231209404
  10. Cheng Chiu, Kaiwen Zheng, Mengxin Xue, Dajiang Du*. Comparative Analysis of Hyaline Cartilage Characteristics and Chondrocyte Potential for Articular Cartilage Repair. Annals of Biomedical Engineering. 2024;52(4):920-933
  • 04/01/2021-03/01/2024
    Natural Science Foundation of Shanghai, ¥200,000, 21ZR1448000
    Study of Co-culture of Wharton's jelly mesenchymal stem cells and costal chondrocytes for articular cartilage regeneration
    Role: Project leader
  • 01/01/2019-12/31/2023
    National Natural Science Foundation of China, ¥2410,000, 81820108020
    Repair of Osteochondral Defect on the Femoral Head using Costal Cartilage
    Role: Principal Investigator
  • 01/01/2016-12/31/2019
    National Natural Science Foundation of China, ¥678,000, 81572112
    Nanoparticle-conjugated Multifunctional Injectable Dual-phase Hydrogel Microsphere System for Intervertebral Disc Injury Repair
    Role: Project leader
  • 01/01/2011-12/31/2013
    National Natural Science Foundation of China, ¥190,000, 31000433
    Fabrication and perfusion culture of anatomically shaped artificial bone using stereolithography
    Role: Project leader
  1. Dajiang Du.  A  Device for Orthopedic Surgery   （Patent No. ZL 2012 1 0417339.2）         
  2. Dajiang Du, Changqing Zhang.  A  Device for Achilles’ Tendon Elongation   （Patent No. ZL201920618692.4）
  3. Dajiang Du, Changqing Zhang, Minghao Zheng, Peichun Hsu, Yigang Huang.  A  Device for Autologous Costal Cartilage Transplantation  （Patent No. ZL20192 0803558.1）                     
  4. Dajiang Du, Changqing Zhang, Minghao Zheng, Peichun Hsu, Yigang Huang.  A  Device for Dislocation of Femoral Head  （Patent No. ZL 2019 2 0802468.0）
  5. Changqing Zhang, Dajiang Du. Costal Cartilage Graft for Repairing Articular Cartilage Defects, 2021-05-18, Canada, 305068.
  6. Dajiang Du, Changqing Zhang.  A Flexible External Fixator for Hip  （Patent No. ZL202022286015.2）
  7. Dajiang Du, Changqing Zhang.  A Fixating Device for Knee to Control  The Flexional and Rotational Position of Hip Joint（Patent No. ZL 202122820905.1）
  8. Dajiang Du, Changqing Zhang. Device, Kit for Repairing and Fixing Articular Cartilage, and Method for the Same, 2023-11-14, Canada, 3129172.

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