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DONG Zhixia
- Graduate Supervisor, Associate Chief Physician
- Department: Gastroenterology
- Research Area: Biology
- Research Interests: Clinical and basic research on gallstone and metabolism-related diseases
- Contact: dzhixia2013@163.com
- Joint PhD from Sydney University, 2010-2012
- PhD from Shanghai Jiao Tong University, 2013
- Dong Z*, Zhuang Q, Ye X, Ning M, Wu S, Lu L, Wan X. Adiponectin Inhibits NLRP3 Inflammasome Activation in Nonalcoholic Steatohepatitis via AMPK-JNK/ErK1/2-NFκB/ROS Signaling Pathways. Front Med (Lausanne). 2020 Nov 5;7: 546445.
- Dong Z*, Zhuang Q, Ning M, Wu S, Lu L, Wan X. Palmitic acid stimulates NLRP3 inflammasome activation through TLR4-NF-κB signal pathway in hepatic stellate cells. Ann Transl Med. 2020 Mar;8(5):168.
- Ye X, Huang D, Dong Z*, Wang X, Ning M, Xia J, Shen S, Wu S, Shi Y, Wang J, Wan X. FXR Signaling-Mediated Bile Acid Metabolism Is Critical for Alleviation of Cholesterol Gallstones by Lactobacillus Strains. Microbiol Spectr. 2022 Oct 26;10(5): e0051822.
- Zhuang Q, Cheng J, Xia J, Ning M, Wu S, Shen S, Shi Y, Huang D, Dong Z*, Wan X. Gypenosides Prevent and Dissolve Cholesterol Gallstones by Modulating the Homeostasis of Cholesterol and Bile Acids. Front Med (Lausanne). 2022 Apr 4;9: 818144.
- Zhuang Q, Ye X, Shen S, Cheng J, Shi Y, Wu S, Xia J, Ning M, Dong Z*, Wan X. Astragalus Polysaccharides Ameliorate Diet-Induced Gallstone Formation by Modulating Synthesis of Bile Acids and the Gut Microbiota. Front Pharmacol. 2021 Jul 1;12: 701003
- Ye X, Shen S, Xu Z, Zhuang Q, Xu J, Wang J, Dong Z*, Wan X. Sodium butyrate alleviates cholesterol gallstones by regulating bile acid metabolism. Eur J Pharmacol. 2021 Oct 5;908:174341.
- Shen S, Huang D, Qian S, Ye X, Zhuang Q, Wan X, Dong Z. Hyodeoxycholic acid attenuates cholesterol gallstone formation via modulation of bile acid metabolism and gut microbiota. Eur J Pharmacol. 2023 Sep 15;955:175891
- Huang D, Shen S, Zhuang Q, Ye X, Qian Y, Dong Z, Wan X. Ganoderma lucidum polysaccharide ameliorates cholesterol gallstone formation by modulating cholesterol and bile acid metabolism in an FXR-dependent manner. Chin Med. 2024 Jan 24;19(1):16.
- Dong Z, Xia J, Wan X. A rare helicobacter pylori infection-negative early gastric cancer in a young man with primary hypertrophic osteoarthropathy. Endoscopy.2022;54(11):E612-E614.
- [10] Dong Z, Wu S, Xia J, Liu D, Qian Y, Wan X. A unique case of well-differentiated gastric-type adenocarcinoma coexisting with a gastric adenocarcinoma of the fundic gland in a Helicobacter pylori-uninfected stomach. Endoscopy. 2023;55(S 01):E1144-E1145.
