DING Jun  

  • Associate Chief Physician
  • Department: Neurosurgery
  • Research Area: Surgery (Neurosurgery)
  • Research Interests: Neural regeneration research after traumatic brain injury
  • Contact: djdjdoc@126.com
  • PhD from Shanghai Jiao Tong University School of  Medicine, 2014
  • MD from Shanghai Jiao Tong University School of Medicine, 2011
  • Graduate Supervisor of Jinzhou Medical University
  1. Jing Y, Zhang L, Chen SW, Guo Y, Ju, SM, Yuan F, Chen H, Yang DX, Tian HL, Xu ZM, Ding J. Inhibition of PHACTR-1 plays a neuroprotective function by suppressing neuroinflammation and cell apoptosis after traumatic brain injury. Neural Regen Res. 2023;18(7):1578-1583. (IF 6.058, Q1) (通讯作者)
  2. Cai L#, Gong Q#, Qi L#, Xu T, Suo Q, Li X, Wang W, Jing Y, Yang D, Xu Z, Yuan F, Tang Y, Yang G, Ding J*, Chen H*, Tian H*. ACT001 attenuates microglia-mediated neuroin ammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway. Cell Communication and Signaling (2022) 20:56. 
  3. Yu H#, Ding J#, Zhu H#, Jing Y, Zhou H, Tian H, Tang K, Wang G, Wang X*. LOXL1 confers antiapoptosis and promotes gliomagenesis through stabilizing BAG2 . Cell Death and Differentiation. 2020; 27: 3021-3036. 
  4. Ding J#, Zhang L#*, Chen S#, Cao H, Xu C, Wang X. lncRNA CCAT2 Enhanced Resistance of Glioma Cells Against Chemodrugs by Disturbing the Normal Function of miR-424 . OncoTargets and Therapy. 2020; 13: 1431-1445. 
  5. Jing Y#, Zhang L#, Xu Z#, Chen H, Ju S, Ding J*, Guo Y*, Tian H*. Phosphatase Actin Regulator-1 (PHACTR-1) Knockdown Suppresses Cell Proliferation and Migration and Promotes Cell Apoptosis in the bEnd.3 Mouse Brain Capillary Endothelial Cell Line. Med Sci Monit. 2019; 25: 1291-1300. 
  6. Jing Y#, Yang DX#, Wang W, Yuan F, Chen H, Ding J*, Geng Z*, Tian H*. Aloin Protects Against Blood-Brain Barrier Damage After Traumatic Brain Injury in Mice. Neuroscience Bulletin. 2020; 36: 625-638. 
  7. Jing Y#, Yang D#, Fu Y#, Wang W, Yang G, Yuan F, Chen H, Ding J*, Chen S*, Tian H*. Neuroprotective Effects of Serpina3k in Traumatic Brain Injury. Frontiers in Neurology. 2019; 10: 1215. 
  8. Ding J, Guo J, Yuan Q, Yuan F, Chen H, Tian H*. Inhibition of phosphatase and tensin homolog deleted on chromosome 10 decreases rat cortical neuron injury and blood-brain barrier permeability, and improves neurological functional recovery in traumatic brain injury model. PLoS One. 2013;8:e80429.
  9. Dai D#, Yuan Q#, Sun Y#, Yuan F, Su Z, Ding J*, Tian H*. Impact of thoracic injury on traumatic brain injury outcome. PLoS One. 2013;8:e74204. 
  10. Ding J, Yuan F, Guo Y, Chen SW, Gao WW, Wang G, Cao HL, Ju SM, Chen H, Zhang PQ, Tian HL*. A prospective clinical study of routine repeat computed tomography (CT) after traumatic brain injury (TBI). Brain Inj. 2012;26:1211-6. 
  • 01/01/2016-12/31/2018
    National Natural Science Foundation of China (Key Program), ¥175,000, 81501048
    The effect of Phactr-1 on the repair of cerebrovascular endothelial cells and blood-brain barrier injury after trauma and its molecular mechanism
    Role: Principal Investigator
  • 10/01/2022-09/30/2025
    Project of Shanghai 6th People's Hospital The mechanism of CD4 + Foxp3 + Tregs regulating microglia polarization to promote the repair of nerve injury after TBI
    Role: Project leader
  1. [Chen Hao, Xue Lixia, Ding Jun, Chen Jiong, Cui Yuhui, Yuan Fang] (2023), “A intracranial pressure reducing composition and its use method”, ZL 202310334502.7 
  2. [Tian Hengli, Cai Lin, Tian Chunqi, Gong Qiuyuan, Chen Hao, Yuan Fang, Ding Jun] (2023), “Application of laughing lactone and its derivatives in the treatment of traumatic brain injury”, ZL 202111372558.9

Member and secretary of the district and county committee of the neurosurgery branch of Shanghai Medical Association, member of the basic and translational group of the neurosurgery branch of Shanghai Medical Association, and member of the Chinese Society of Neuroscience. Reviewer and guest editor of Journal of Neuroinflammation, Frontiers in Public Health and other magazines.