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DENG Hui
- Doctoral Supervisor, Professor
- Department: Dermatology
- Research Area: Dermatology and Venereology
- Research Interests: Pathogenesis of psoriasis; photobiology
- Contact: hdeng@sjtu.edu.cn
- Fellowship, Huashan Hospital, Fudan university, 2004
- MD from Huashan Hospital, Fudan university, 2004
- PhD from Henan Medical University, 2001
- MD from Henan Medical Universityy, 1998
- Director, Department of Dermatology, Shanghai Sixth People's Hospital
- Meng Q, Bai M, Guo M, Li Z, Liu W, Fan X, Sun R, Yang X, Yuan D, Shi Y, Deng H. Inhibition of Serum- and Glucocorticoid-Regulated Protein Kinase-1 Aggravates Imiquimod-Induced Psoriatic Dermatitis and Enhances Proinflammatory Cytokine Expression through the NF-kB Pathway. J Invest Dermatol. 2023 Jan 6:S0022-202X(23)00007-6.
- Deng H, Li F, Li H, Deng Y, Liu J, Wang D, Han G, Wang XJ, Zhang Q. CtBP1 overexpression in keratinocytes perturbs skin homeostasis. J Invest Dermatol. 2014 May;134(5):1323-1331.
- Deng H, Liu J, Deng Y, Han G, Shellman YG, Robinson SE, Tentler JJ, Robinson WA, Norris DA, Wang XJ, Zhang Q. CtBP1 is expressed in melanoma and represses the transcription of p16INK4a and Brca1. J Invest Dermatol. 2013 May;133(5):1294-301.
- Zhuang H, Wang X, Guo M, Meng Q, Liu N, Wei M, Shi Y, Deng H. Identification of Chemokines-Related miRNAs as Potential Biomarkers in Psoriasis Based on Integrated Bioinformatics Analysis. Comb Chem High Throughput Screen. 2023;26(7):1400-1413.
- Fan X, Yan K, Meng Q, Sun R, Yang X, Yuan D, Li F, Deng H. Abnormal expression of SIRTs in psoriasis: Decreased expression of SIRT 1-5 and increased expression of SIRT 6 and 7. Int J Mol Med. 2019 Jul;44(1):157-171.
- Wang B, Deng H, Hu Y, Han L, Huang Q, Fang X, Yang K, Wu S, Zheng Z, Yawalkar N, Zhang Z, Yan K. The difference of lipid profiles between psoriasis with arthritis and psoriasis without arthritis and sex-specific downregulation of methotrexate on the apolipoprotein B/apolipoprotein A-1 ratio. Arthritis Res Ther. 2022 Jan 7;24(1):17.
- Zhu J, Han L, Liu R, Zhang Z, Huang Q, Fang X, Yang K, Huang G, Zheng Z, Yawalkar N, Deng H, Yan K. Identification of proteins associated with development of psoriatic arthritis in peripheral blood mononuclear cells: a quantitative iTRAQ-based proteomics study. J Transl Med. 2021 Aug 3;19(1):331.
- Meng Q, Guo M, Yuan D, Deng H. A case of early localized scleroderma that was manifested as a port-wine stain. Postepy Dermatol Alergol. 2021 Aug;38(4):701-702.
- Li FL, Deng H, Wang HW, Xu R, Chen J, Wang YF, Li X, Fan B, Li B. Effects of external application of Chinese medicine on diabetic ulcers and the expressions of β-catenin, c-myc and K6. Chin J Integr Med. 2011 Apr;17(4):261-6.
- Deng H, Yan C, Xiao T, Yuan D, Xu J. Total glucosides of Paeonia lactiflora Pall inhibit vascular endothelial growth factor-induced angiogenesis. J Ethnopharmacol. 2010 Feb 17;127(3):781-5.
- 01/01/2023-12/31/2026
National Natural Science Foundation of China, ¥5,000,000, 82273521
SIRT3 participate in the pathogenesis of psoriasis through modulating Unfolded Protein Response and metabolic reprogramming
Role: Principal Investigator - 01/01/2016-12/31/2019
National Key Research and Development Project, ¥5,000,000, 81673054
The role of SIRT7 in the pathology of psoriasis.
Role: Project leader
